2024
Endometrial stromal cell signaling and microRNA exosome content in women with adenomyosis
Zipponi M, Cacciottola L, Camboni A, Stratopoulou C, Taylor H, Dolmans M. Endometrial stromal cell signaling and microRNA exosome content in women with adenomyosis. Molecular Human Reproduction 2024, gaae044. PMID: 39673794, DOI: 10.1093/molehr/gaae044.Peer-Reviewed Original ResearchStromal cell signalsMenstrual phaseHealthy subjectsPresence of endometrial glandsPathogenesis of adenomyosisCompared to controlsEndometrial biopsyEndometrial glandsEutopic endometriumStromal compartmentAdenomyosisAdenomyosis developmentMolecular mechanismsCell signalingLesion establishmentStromal cellsNanoparticle tracking analysisFlow cytometryEpithelial glandsParacrine signalingQuality of lifeSecreted exosomesIntercellular communicationExosomal contentsReproductive health
2012
A polymorphism in a let‐7 microRNA binding site of KRAS in women with endometriosis
Grechukhina O, Petracco R, Popkhadze S, Massasa E, Paranjape T, Chan E, Flores I, Weidhaas JB, Taylor HS. A polymorphism in a let‐7 microRNA binding site of KRAS in women with endometriosis. EMBO Molecular Medicine 2012, 4: 206-217. PMID: 22307873, PMCID: PMC3376847, DOI: 10.1002/emmm.201100200.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsKRAS-variantCultured endometrial stromal cellsStromal cellsAbnormal endometrial growthDe novo endometriosisProgesterone receptor levelsRelatives of womenEndometrial xenograftsKRAS resultsLCS6 polymorphismEndometrial growthReproductive ageKRAS mutationsReceptor levelsMurine modelEndometriosisEndometriosis riskControl populationVariant allelesKRAS mRNAProtein expressionKRASWomenKRAS protein
2007
Demonstration of Multipotent Stem Cells in the Adult Human Endometrium by In Vitro Chondrogenesis
Wolff EF, Wolff AB, Hongling Du, Taylor HS. Demonstration of Multipotent Stem Cells in the Adult Human Endometrium by In Vitro Chondrogenesis. Reproductive Sciences 2007, 14: 524-533. PMID: 17959881, DOI: 10.1177/1933719107306896.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsMultipotent stem cellsFallopian tubeType II collagenStem cellsReproductive-aged womenHuman articular cartilageEndometrial stem cellsAdult human endometriumII collagenMultilineage differentiationArticular cartilageBenign diseaseEndometrial tissueExtramedullary tissuesHuman endometriumCell pelletsEndometriumChondrogenic mediumStromal cellsLigament cellsSulfated glycosaminoglycansGrowth factorProgenitor cellsCell types