2022
Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019
Eldridge N, Wang Y, Metersky M, Eckenrode S, Mathew J, Sonnenfeld N, Perdue-Puli J, Hunt D, Brady PJ, McGann P, Grace E, Rodrick D, Drye E, Krumholz HM. Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019. JAMA 2022, 328: 173-183. PMID: 35819424, PMCID: PMC9277501, DOI: 10.1001/jama.2022.9600.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAdultAgedAged, 80 and overCross InfectionCross-Sectional StudiesDrug-Related Side Effects and Adverse ReactionsFemaleHeart FailureHospitalizationHumansMaleMedicareMiddle AgedMyocardial InfarctionPatient SafetyPneumoniaPostoperative ComplicationsPressure UlcerRisk AssessmentSurgical Procedures, OperativeUnited StatesConceptsMajor surgical proceduresAcute myocardial infarctionAdverse event ratesGeneral adverse eventsAdverse eventsHeart failureAdverse drug eventsAcute care hospitalsMyocardial infarctionHospital-acquired infectionsSurgical proceduresEvent ratesHospital dischargeCare hospitalDrug eventsMedicare Patient Safety Monitoring SystemSerial cross-sectional studyPatient safetyUS acute care hospitalsHospital adverse eventsSignificant decreaseSurgical procedure groupsCross-sectional studyRisk-adjusted ratesAdult patientsData-Driven Individualized Surgical Decision-making
Mori M, Spertus JA, Krumholz HM. Data-Driven Individualized Surgical Decision-making. JAMA Surgery 2022, 157: 93-94. PMID: 34817547, DOI: 10.1001/jamasurg.2021.5614.Peer-Reviewed Original ResearchClinical Decision-MakingHumansRandomized Controlled Trials as TopicSurgical Procedures, OperativeUnited States
2019
Tapping Into Underutilized Healthcare Data in Clinical Research
Mori M, Schulz WL, Geirsson A, Krumholz HM. Tapping Into Underutilized Healthcare Data in Clinical Research. Annals Of Surgery 2019, Publish Ahead of Print: &na;. PMID: 30998537, DOI: 10.1097/sla.0000000000003329.Peer-Reviewed Original Research
2014
National Trends in Patient Safety for Four Common Conditions, 2005–2011
Wang Y, Eldridge N, Metersky ML, Verzier NR, Meehan TP, Pandolfi MM, Foody JM, Ho SY, Galusha D, Kliman RE, Sonnenfeld N, Krumholz HM, Battles J. National Trends in Patient Safety for Four Common Conditions, 2005–2011. New England Journal Of Medicine 2014, 370: 341-351. PMID: 24450892, PMCID: PMC4042316, DOI: 10.1056/nejmsa1300991.Peer-Reviewed Original ResearchConceptsCongestive heart failureAcute myocardial infarctionMore adverse eventsProportion of patientsAdverse event ratesAdverse eventsHeart failureMyocardial infarctionRate of occurrenceCommon medical conditionsMedical recordsMedicare patientsMedical conditionsPatientsSurgeryInfarctionPneumoniaHospitalizationPatient safetyNational trendsMonitoring System dataSignificant declineFailureProportionRate
2008
Cerebrovascular Disease Risk in Older Head and Neck Cancer Patients After Radiotherapy
Smith GL, Smith BD, Buchholz TA, Giordano SH, Garden AS, Woodward WA, Krumholz HM, Weber RS, Ang K, Rosenthal DI. Cerebrovascular Disease Risk in Older Head and Neck Cancer Patients After Radiotherapy. Journal Of Clinical Oncology 2008, 26: 5119-5125. PMID: 18725647, PMCID: PMC4879715, DOI: 10.1200/jco.2008.16.6546.Peer-Reviewed Original ResearchConceptsCerebrovascular disease riskNeck cancer patientsDisease riskCerebrovascular eventsCerebrovascular riskCardiac riskCancer patientsNeck cancerTreatment groupsTen-year incidenceProportional hazards regressionDefinitive radiotherapyPostoperative radiotherapyCardiac eventsOlder patientsCerebrovascular diseaseHazards regressionNonmetastatic headMean ageVascular diseaseBaseline riskPatientsSurgeryRadiotherapyControl diagnosisACC/AHA 2008 Guideline Update on Valvular Heart Disease: Focused Update on Infective Endocarditis
Nishimura RA, Carabello BA, Faxon DP, Freed MD, Lytle BW, O'Gara PT, O'Rourke RA, Shah PM, Bonow RO, Carabello BA, Chatterjee K, de Leon AC, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS, Smith SC, Jacobs AK, Buller CE, Creager MA, Ettinger SM, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Page RL, Tarkington LG, Yancy CW. ACC/AHA 2008 Guideline Update on Valvular Heart Disease: Focused Update on Infective Endocarditis. Catheterization And Cardiovascular Interventions 2008, 72: e1-e12. PMID: 18671249, DOI: 10.1002/ccd.21751.Peer-Reviewed Original Research