2024
Internal tremors and vibrations in long COVID: a cross-sectional study
Zhou T, Sawano M, Arun A, Caraballo C, Michelsen T, McAlpine L, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz H. Internal tremors and vibrations in long COVID: a cross-sectional study. The American Journal Of Medicine 2024 PMID: 39069199, DOI: 10.1016/j.amjmed.2024.07.008.Peer-Reviewed Original ResearchNew-onset conditionsInternal tremorLong COVID symptomsCOVID symptomsNon-Hispanic whitesCross-sectional studyQuality of lifeVisual analogue scaleWorse healthHealth statusStudy participantsDemographic characteristicsAnalogue scaleOutcome variablesNeurological conditionsLong COVIDMast cell disordersTreatment experienceHealthComorbiditiesSymptomsMedian agePeopleCell disorders
2019
Characterizing Patient‐Centered Postoperative Recovery After Adult Cardiac Surgery: A Systematic Review
Mori M, Angraal S, Chaudhry SI, Suter LG, Geirsson A, Wallach JD, Krumholz HM. Characterizing Patient‐Centered Postoperative Recovery After Adult Cardiac Surgery: A Systematic Review. Journal Of The American Heart Association 2019, 8: e013546. PMID: 31617435, PMCID: PMC6898802, DOI: 10.1161/jaha.119.013546.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresPostoperative patient-reported outcome measuresAdult cardiac surgeryPostoperative recoveryOutcome measuresCardiac surgerySystematic reviewCoronary artery bypass graftSingle-center settingArtery bypass graftQuality of evidenceWeb of ScienceNociceptive symptomsDiversity of patientsLess comorbidityAdult patientsBypass graftPhysical functionPostacute careElective casesInclusion criteriaDaily livingPatientsStudy participantsCognitive functionAssociation of Income Disparities with Patient-Reported Healthcare Experience
Okunrintemi V, Khera R, Spatz ES, Salami JA, Valero-Elizondo J, Warraich HJ, Virani SS, Blankstein R, Blaha MJ, Pawlik TM, Dharmarajan K, Krumholz HM, Nasir K. Association of Income Disparities with Patient-Reported Healthcare Experience. Journal Of General Internal Medicine 2019, 34: 884-892. PMID: 30783877, PMCID: PMC6544715, DOI: 10.1007/s11606-019-04848-4.Peer-Reviewed Original ResearchConceptsPatient healthcare experienceHealthcare experiencesHigher oddsMedical Expenditure Panel Survey cohortHealthcare providersRepresentative US adult populationUS adult populationTimes higher oddsQuality of careTimes greater oddsLow incomePoor healthcare experiencesRetrospective studyPatient incomePatient levelPatient reportsUS adultsProvider satisfactionGreater oddsPatientsHealth outcomesSurvey cohortAdult populationStudy participantsAspects of access
2018
Accurate estimation of cardiovascular risk in a non-diabetic adult: detecting and correcting the error in the reported Framingham Risk Score for the Systolic Blood Pressure Intervention Trial population
Warner F, Dhruva SS, Ross JS, Dey P, Murugiah K, Krumholz HM. Accurate estimation of cardiovascular risk in a non-diabetic adult: detecting and correcting the error in the reported Framingham Risk Score for the Systolic Blood Pressure Intervention Trial population. BMJ Open 2018, 8: e021685. PMID: 30037874, PMCID: PMC6059296, DOI: 10.1136/bmjopen-2018-021685.Peer-Reviewed Original ResearchConceptsSystolic Blood Pressure Intervention TrialFramingham risk scoreCardiovascular riskRisk scoreStudy populationStudy participantsNon-diabetic adultsTotal study populationHigh-risk populationClinical trial dataClinical trial sitesTrial populationIntervention trialsRisk populationsNew England JournalIndependent investigatorsTrial dataSecondary analysisSPRINT trialSPRINT dataTrialsRiskScoresParticipantsPopulation
2017
Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial)
Dhruva SS, Huang C, Spatz ES, Coppi AC, Warner F, Li SX, Lin H, Xu X, Furberg CD, Davis BR, Pressel SL, Coifman RR, Krumholz HM. Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial). Hypertension 2017, 70: 94-102. PMID: 28559399, DOI: 10.1161/hypertensionaha.117.09221.Peer-Reviewed Original ResearchConceptsAntihypertensive therapySystolic blood pressure responseAdverse cardiovascular eventsFavorable initial responseBlood pressure responseHigher hazard ratioCardiovascular eventsCardiovascular outcomesHazard ratioMultivariable adjustmentHeart failureAverage SBPRandomized trialsOdds ratioCardiovascular diseaseSBPStudy participantsRespondersMonthsPressure responseImmediate respondersALLHATEarly responseInitial responseSuperior discrimination
2015
The Variation in Recovery
Spatz ES, Curry LA, Masoudi FA, Zhou S, Strait KM, Gross CP, Curtis JP, Lansky AJ, Soares Barreto-Filho JA, Lampropulos JF, Bueno H, Chaudhry SI, D'Onofrio G, Safdar B, Dreyer RP, Murugiah K, Spertus JA, Krumholz HM. The Variation in Recovery. Circulation 2015, 132: 1710-1718. PMID: 26350057, PMCID: PMC4858327, DOI: 10.1161/circulationaha.115.016502.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetAlgorithmsAortic DissectionClassificationCoronary DiseaseDiagnostic Techniques, CardiovascularFemaleHumansMaleMedical RecordsMiddle AgedMyocardial InfarctionMyocardiumOxygen ConsumptionPhenotypePlaque, AtheroscleroticProspective StudiesReproducibility of ResultsRisk FactorsSex FactorsTreatment OutcomeYoung AdultConceptsAcute myocardial infarctionCoronary artery diseaseArtery diseaseClinical phenotypeNonobstructive coronary artery diseaseYoung AMI Patients (VIRGO) studyObstructive coronary artery diseaseYoung womenType 2 acute myocardial infarctionBiological disease mechanismsSubset of patientsThird universal definitionUnique clinical phenotypeCulprit lesionClinical characteristicsMyocardial infarctionTherapeutic efficacyUniversal definitionStudy participantsPatientsSupply-demand mismatchYoung adultsDisease mechanismsPatient studiesCurrent classification schemes
2007
Patient Satisfaction With Treatment After Acute Myocardial Infarction: Role of Psychosocial Factors
Barry LC, Lichtman JH, Spertus JA, Rumsfeld JS, Vaccarino V, Jones PG, Plomondon ME, Parashar S, Krumholz HM. Patient Satisfaction With Treatment After Acute Myocardial Infarction: Role of Psychosocial Factors. Psychosomatic Medicine 2007, 69: 115-123. PMID: 17289828, DOI: 10.1097/psy.0b013e31802f2785.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionTreatment satisfactionMyocardial infarctionPsychosocial variablesPsychosocial statusWorse treatment satisfactionSeattle Angina QuestionnairePatient treatment satisfactionProspective cohort studyTreatment Satisfaction ScaleSocial supportDispositional optimismAngina QuestionnaireCohort studyHospital dischargeAMI patientsClinical presentationMean ageMedical historyPatient satisfactionCare indicatorsDepression severityPsychosocial factorsPsychosocial interventionsStudy participants
2002
Reporting the recruitment process in clinical trials: who are these patients and how did they get there?
Gross CP, Mallory R, Heiat A, Krumholz HM. Reporting the recruitment process in clinical trials: who are these patients and how did they get there? Annals Of Internal Medicine 2002, 137: 10-6. PMID: 12093240, DOI: 10.7326/0003-4819-137-1-200207020-00007.Peer-Reviewed Original ResearchConceptsNumber of personsMedian proportionPotential study participantsMedical journalsClinical trialsEligible personsHigh-impact medical journalsGeneral populationRCTsMajor medical journalsStudy participantsPatient recruitment processStudy sampleTrialsEligibilityPersonsExplicit reviewProportionEnrollment processParticipantsPatients