2023
Do PCI Facility Openings and Closures Affect AMI Outcomes Differently in High- vs Average-Capacity Markets?
Shen Y, Krumholz H, Hsia R. Do PCI Facility Openings and Closures Affect AMI Outcomes Differently in High- vs Average-Capacity Markets? JACC Cardiovascular Interventions 2023, 16: 1129-1140. PMID: 37225284, PMCID: PMC10229059, DOI: 10.1016/j.jcin.2023.02.010.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionPCI hospitalsSame-day percutaneous coronary interventionHealth outcomesHigh-volume PCI hospitalsHospital PCI volumeRetrospective cohort studyAcute myocardial infarctionPercentage point decreasePatient health outcomesHospital revascularizationCohort studyCoronary interventionAMI outcomesPCI volumePoint decreasePoor outcomePCI facilitiesMyocardial infarctionRelative increaseHospital openingPatientsHospital availabilityHospitalHospital closures
2020
Evaluation of STEMI Regionalization on Access, Treatment, and Outcomes Among Adults Living in Nonminority and Minority Communities
Hsia RY, Krumholz H, Shen YC. Evaluation of STEMI Regionalization on Access, Treatment, and Outcomes Among Adults Living in Nonminority and Minority Communities. JAMA Network Open 2020, 3: e2025874. PMID: 33196809, PMCID: PMC7670311, DOI: 10.1001/jamanetworkopen.2020.25874.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBlack or African AmericanCaliforniaCause of DeathCohort StudiesFemaleHealth Services AccessibilityHealthcare DisparitiesHispanic or LatinoHospitalizationHumansMaleMiddle AgedMinority GroupsMortalityNon-Randomized Controlled Trials as TopicPercutaneous Coronary InterventionRegional Medical ProgramsResidence CharacteristicsST Elevation Myocardial InfarctionTime-to-TreatmentWhite PeopleConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionPercutaneous coronary interventionPCI-capable hospitalsZip codesNon-Hispanic whitesPatient's countyCause mortalityCohort studyCoronary interventionPCI hospitalsPCI treatmentWhite patientsCapable hospitalsMyocardial infarctionTop tertileInpatient dataMAIN OUTCOMEPatientsSTEMI regionalizationSmall improvementHospitalPotential mechanismsSame dayHispanic population
2014
Payments for Acute Myocardial Infarction Episodes-of-Care Initiated at Hospitals With and Without Interventional Capabilities
Ben-Josef G, Ott LS, Spivack SB, Wang C, Ross JS, Shah SJ, Curtis JP, Kim N, Krumholz HM, Bernheim SM. Payments for Acute Myocardial Infarction Episodes-of-Care Initiated at Hospitals With and Without Interventional Capabilities. Circulation Cardiovascular Quality And Outcomes 2014, 7: 882-888. PMID: 25387777, DOI: 10.1161/circoutcomes.114.000927.Peer-Reviewed Original ResearchConceptsNon-PCI hospitalsCoronary artery bypass graft ratesPCI hospitalsAcute myocardial infarctionMyocardial infarctionPercutaneous coronary intervention capabilityAcute myocardial infarction admissionsLower revascularization ratesPrincipal discharge diagnosisTreatment of patientsMyocardial infarction admissionsHigh rateMyocardial infarction episodeGraft ratePCI capabilityPCI useIndex admissionRevascularization ratesClinical characteristicsPatient demographicsDays postadmissionDischarge diagnosisMedicare patientsCare proceduresMedicare fee
2010
Differences in Patient Survival After Acute Myocardial Infarction by Hospital Capability of Performing Percutaneous Coronary Intervention: Implications for Regionalization
Chen J, Krumholz HM, Wang Y, Curtis JP, Rathore SS, Ross JS, Normand SL, Schreiner GC, Mulvey G, Nallamothu BK. Differences in Patient Survival After Acute Myocardial Infarction by Hospital Capability of Performing Percutaneous Coronary Intervention: Implications for Regionalization. JAMA Internal Medicine 2010, 170: 433-439. PMID: 20212179, PMCID: PMC2900156, DOI: 10.1001/archinternmed.2009.538.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesNon-PCI hospitalsPercutaneous coronary interventionAcute myocardial infarctionHospital referral regionsPCI hospitalsHealth care regionCoronary interventionAMI patientsMyocardial infarctionCare regionLower risk-standardized mortality ratesSame hospital referral regionService beneficiaries 65 yearsBeneficiaries 65 yearsMagnitude of benefitPatient survivalAMI careReferral regionsOutcome differencesMedicare feeMortality rateHospitalHospital capabilitiesInfarction
2006
Regionalization of ST-Segment Elevation Acute Coronary Syndromes Care Putting a National Policy in Proper Perspective
Rathore SS, Epstein AJ, Nallamothu BK, Krumholz HM. Regionalization of ST-Segment Elevation Acute Coronary Syndromes Care Putting a National Policy in Proper Perspective. Journal Of The American College Of Cardiology 2006, 47: 1346-1349. PMID: 16580519, PMCID: PMC2789345, DOI: 10.1016/j.jacc.2005.11.053.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCISTEMI patientsFibrinolytic therapyPCI hospitalsST-segment elevation myocardial infarction (STEMI) careAcute coronary syndrome careHigh-volume PCI hospitalsHigh-risk STEMI patientsElevation Myocardial Infarction CareHigh-volume hospitalsLow-volume hospitalsPercutaneous coronary interventionMyocardial infarction careCardiac care facilitiesHealth care resourcesHealth care systemInitial hospitalPCI patientsCoronary interventionU.S. health care systemAverage patientSingle deathCare facilitiesPatientsDriving Times and Distances to Hospitals With Percutaneous Coronary Intervention in the United States
Nallamothu BK, Bates ER, Wang Y, Bradley EH, Krumholz HM. Driving Times and Distances to Hospitals With Percutaneous Coronary Intervention in the United States. Circulation 2006, 113: 1189-1195. PMID: 16520425, DOI: 10.1161/circulationaha.105.596346.Peer-Reviewed Original ResearchConceptsNon-PCI hospitalsPercutaneous coronary interventionST-elevation myocardial infarctionPCI hospitalsAdult populationCoronary interventionPrehospital triage protocolsAdults 18 yearsCross-sectional studyAmerican Hospital Association Annual SurveyHospital-level dataMedian timeMyocardial infarctionDirect referralTriage protocolHospitalTimely accessPatientsUnited StatesMinutesCensus tract-level dataInterventionTract-level dataTransport timePopulation
2005
Times to Treatment in Transfer Patients Undergoing Primary Percutaneous Coronary Intervention in the United States
Nallamothu BK, Bates ER, Herrin J, Wang Y, Bradley EH, Krumholz HM. Times to Treatment in Transfer Patients Undergoing Primary Percutaneous Coronary Intervention in the United States. Circulation 2005, 111: 761-767. PMID: 15699253, DOI: 10.1161/01.cir.0000155258.44268.f8.Peer-Reviewed Original ResearchConceptsPrimary PCIPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionPercutaneous coronary interventionBalloon timeTransfer patientsCoronary interventionInterhospital transferMyocardial infarctionTotal doorRecent clinical trialsSpecific ECG findingsMultivariable hierarchical modelsChest painHospital presentationInitial hospitalFibrinolytic therapyPCI hospitalsPrimary outcomeSymptom onsetComorbid conditionsTreatment delayECG findingsHospital characteristicsNational registry