2012
A Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest
Chan PS, Spertus JA, Krumholz HM, Berg RA, Li Y, Sasson C, Nallamothu BK, Investigators F. A Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest. JAMA Internal Medicine 2012, 172: 947-953. PMID: 22641228, PMCID: PMC3517176, DOI: 10.1001/archinternmed.2012.2050.Peer-Reviewed Original ResearchConceptsFavorable neurological survivalHospital cardiac arrestNeurological survivalCardiac arrestNeurological statusDerivation cohortValidation cohortInitial cardiac arrest rhythmIn-Hospital Cardiac ArrestBaseline neurological statusFavorable neurological statusGuidelines-Resuscitation registryCardiac arrest rhythmSevere neurological deficitsPulseless ventricular tachycardiaMultivariate logistic regressionSimple prediction toolRenal insufficiencyArrest rhythmNeurological deficitsHepatic insufficiencyMechanical ventilationMalignant diseaseVentricular tachycardiaInitial survivors
2011
Gender Differences in Presentation, Management, and In-Hospital Outcomes for Patients with AMI in a Lower-Middle Income Country: Evidence from Egypt
Butala NM, Desai MM, Linnander EL, Wong YR, Mikhail DG, Ott LS, Spertus JA, Bradley EH, Aaty AA, Abdelfattah A, Gamal A, Kholeif H, Baz M, Allam AH, Krumholz HM. Gender Differences in Presentation, Management, and In-Hospital Outcomes for Patients with AMI in a Lower-Middle Income Country: Evidence from Egypt. PLOS ONE 2011, 6: e25904. PMID: 22022463, PMCID: PMC3192760, DOI: 10.1371/journal.pone.0025904.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHospital outcomesFemale patientsInitial presentationClinical managementDiagnosis of AMIIncome countriesIn-Hospital OutcomesOutcomes of patientsTime of presentationMultivariate logistic regressionGender differencesQuality of careLow-middle income countriesHospital mortalityHospital deathDiabetes mellitusHeart failureAtrial fibrillationHigher BMIMyocardial infarctionCardiovascular diseaseRegistry dataHigh-income countriesEgyptian hospitals
2008
Contemporary evidence: baseline data from the D2B Alliance
Bradley EH, Nallamothu BK, Stern AF, Byrd JR, Cherlin EJ, Wang Y, Yuan C, Nembhard I, Brush JE, Krumholz HM. Contemporary evidence: baseline data from the D2B Alliance. BMC Research Notes 2008, 1: 23. PMID: 18710480, PMCID: PMC2525646, DOI: 10.1186/1756-0500-1-23.Peer-Reviewed Original ResearchST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionD2B AllianceHospital characteristicsEvidence-based strategiesD2B timeU.S. hospitalsElevation myocardial infarctionPercutaneous coronary interventionMultivariate logistic regressionCross-sectional studyBalloon (D2B) AllianceCoronary interventionPrompt treatmentMyocardial infarctionHospitalWeb-based surveyLogistic regressionBaseline dataPatientsKey strategyCurrent practiceBackgroundLessInfarctionResultsOf
2006
Relation Between Medicare Screening Reimbursement and Stage at Diagnosis for Older Patients With Colon Cancer
Gross CP, Andersen MS, Krumholz HM, McAvay GJ, Proctor D, Tinetti ME. Relation Between Medicare Screening Reimbursement and Stage at Diagnosis for Older Patients With Colon Cancer. JAMA 2006, 296: 2815-2822. PMID: 17179458, DOI: 10.1001/jama.296.23.2815.Peer-Reviewed Original ResearchConceptsProximal colon lesionsColon lesionsMedicare beneficiariesColon cancerColonoscopy useEnd Results-MedicareProportion of patientsUse of colonoscopyEnd Results (SEER) areasMultivariate logistic regressionReimbursement policiesColon cancer screeningColon cancer riskMultivariate Poisson regressionYears of ageReimbursement policy changesSigmoidoscopy useEligible patientsOlder patientsColorectal cancerCancer screeningPrimary diagnosisScreening modalityColon cancer diagnosisCancer risk
2005
Enrollment of Older Persons in Cancer Trials After the Medicare Reimbursement Policy Change
Gross CP, Wong N, Dubin JA, Mayne ST, Krumholz HM. Enrollment of Older Persons in Cancer Trials After the Medicare Reimbursement Policy Change. JAMA Internal Medicine 2005, 165: 1514-1520. PMID: 16009867, DOI: 10.1001/archinte.165.13.1514.Peer-Reviewed Original ResearchConceptsOlder patientsCancer trialsReimbursement policy changesOlder personsPatients' sociodemographic characteristicsTrial exclusion criteriaMultivariate logistic regressionProstate cancer trialsProportion of participantsNational Cancer InstituteRoutine care costsSignificant changesClinical trialsPrimary study sampleExclusion criteriaTrial participantsCancer InstitutePatientsPrimary analysisCare costsMultivariate analysisSecondary analysisSociodemographic characteristicsLogistic regressionCancer types