2022
Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy
Mori M, Mark DB, Khera R, Lin H, Jones P, Huang C, Lu Y, Geirsson A, Velazquez EJ, Spertus JA, Krumholz HM. Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy. American Heart Journal 2022, 254: 12-22. PMID: 35932911, DOI: 10.1016/j.ahj.2022.07.007.Peer-Reviewed Original ResearchConceptsCoronary artery bypass surgeryGuideline-directed medical therapyTreatment choiceBetter outcomesIschemic cardiomyopathyQOL outcomesQoL dataKansas City Cardiomyopathy Questionnaire overall summary scoreQOL trajectoriesOutcome patternsIschemic Heart Failure (STICH) trialHeart Failure TrialMain baseline predictorsArtery bypass surgeryOverall summary scoreDifferent treatment choicesLogistic regression modelsBypass surgeryMedical therapySurgical treatmentFailure TrialLife scoresQOL scoresPatient's probabilityBaseline predictors
2020
Sex Differences in 1‐Year Health Status Following Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction: Results From the China PEACE Prospective Study
Zheng X, Dreyer RP, Curtis JP, Liu S, Xu X, Bai X, Li X, Zhang H, Wang S, Masoudi FA, Spertus JA, Li J, Krumholz HM, Group F. Sex Differences in 1‐Year Health Status Following Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction: Results From the China PEACE Prospective Study. Journal Of The American Heart Association 2020, 9: e014421. PMID: 32131687, PMCID: PMC7335522, DOI: 10.1161/jaha.119.014421.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute myocardial infarctionSAQ Summary ScoreCoronary interventionHealth status outcomesMyocardial infarctionHealth statusSummary scoresSAQ qualityAngina frequencyStatus outcomesPercutaneous coronary intervention studiesSAQ angina frequency scoreAngina frequency scoreCoronary Intervention StudyMarginal clinical significanceSAQ angina frequencyCardiac risk factorsChinese tertiary hospitalBackground Sex differencesSex differencesMultivariable adjustmentDiabetes mellitusTertiary hospitalLife scores
2011
Effect of Living Alone on Patient Outcomes After Hospitalization for Acute Myocardial Infarction
Bucholz EM, Rathore SS, Gosch K, Schoenfeld A, Jones PG, Buchanan DM, Spertus JA, Krumholz HM. Effect of Living Alone on Patient Outcomes After Hospitalization for Acute Myocardial Infarction. The American Journal Of Cardiology 2011, 108: 943-948. PMID: 21798499, PMCID: PMC3670597, DOI: 10.1016/j.amjcard.2011.05.023.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionSeattle Angina QuestionnaireMyocardial infarctionPatient outcomesLife 1 yearRegistry of patientsHealth status measurementPhysical health componentAngina QuestionnaireMultivariable adjustmentLife scoresTreatment characteristicsComparable riskOutcome measurementsPatientsReadmissionHealth componentHealth statusMean qualityMortalityStatus measurementsComponent scaleOutcomesInfarctionSocial support
2007
Financial Barriers to Health Care and Outcomes After Acute Myocardial Infarction
Rahimi AR, Spertus JA, Reid KJ, Bernheim SM, Krumholz HM. Financial Barriers to Health Care and Outcomes After Acute Myocardial Infarction. JAMA 2007, 297: 1063-1072. PMID: 17356027, DOI: 10.1001/jama.297.10.1063.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth care servicesCare servicesMyocardial infarctionCardiac rehospitalizationSAQ qualityCause rehospitalizationLife scoresFinancial barriersMulticenter US studyHealth care outcomesProspective registryBaseline prevalenceRehospitalizationHigh riskMedicationsCare outcomesWorse recoveryInfarctionPrevalenceHealth careUS studiesPatientsPoor qualityOutcomes
2004
Quality of life after aortic valve replacement with tissue and mechanical implants
Sedrakyan A, Hebert P, Vaccarino V, Paltiel AD, Elefteriades JA, Mattera J, Lin Z, Roumanis SA, Krumholz HM. Quality of life after aortic valve replacement with tissue and mechanical implants. Journal Of Thoracic And Cardiovascular Surgery 2004, 128: 266-272. PMID: 15282464, DOI: 10.1016/j.jtcvs.2003.12.014.Peer-Reviewed Original ResearchConceptsAortic valve replacementQuality of lifeMechanical valve implantsMechanical valve recipientsValve replacementValve recipientsLife scoresValve implantsTissue valvesMechanical valvesMedical Outcomes Trust Short FormPopulation normsYale-New Haven HospitalMechanical valve replacementRate of complicationsUS population normsTissue valve replacementPrognostic factorsRole limitationsOnly significant differenceHealth SurveyAnalysis of covarianceBaseline qualityMean qualityPatients