2020
Association Between Depressive Symptoms and Incident Cardiovascular Diseases
Harshfield EL, Pennells L, Schwartz JE, Willeit P, Kaptoge S, Bell S, Shaffer JA, Bolton T, Spackman S, Wassertheil-Smoller S, Kee F, Amouyel P, Shea SJ, Kuller LH, Kauhanen J, van Zutphen EM, Blazer DG, Krumholz H, Nietert PJ, Kromhout D, Laughlin G, Berkman L, Wallace RB, Simons LA, Dennison EM, Barr ELM, Meyer HE, Wood AM, Danesh J, Di Angelantonio E, Davidson KW. Association Between Depressive Symptoms and Incident Cardiovascular Diseases. JAMA 2020, 324: 2396-2405. PMID: 33320224, PMCID: PMC7739139, DOI: 10.1001/jama.2020.23068.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHazard ratioStroke eventsCardiovascular diseaseCorresponding incidence ratesDepressive symptomsHigher depression scoresCHD eventsCVD eventsCVD incidencePooled analysisIncidence rateDepression scoresNonfatal coronary heart diseasePatient Health Questionnaire-2Epidemiological Studies Depression ScaleIncident cardiovascular diseasePHQ-2 scoreAdditional risk factorsBaseline depressive symptomsSelf-reported depressive symptomsCES-D scoresEmerging Risk Factors CollaborationIndividual participant dataUK Biobank
1995
Prognosis of left ventricular geometric patterns in the Framingham heart study
Krumholz H, Larson M, Levy D. Prognosis of left ventricular geometric patterns in the Framingham heart study. Journal Of The American College Of Cardiology 1995, 25: 879-884. PMID: 7884091, DOI: 10.1016/0735-1097(94)00473-4.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsLeft ventricular massTraditional cardiovascular risk factorsLeft ventricular geometric patternsVentricular geometric patternsVentricular massConcentric hypertrophyLeft ventricular geometryRisk factorsPopulation-based sampleCardiovascular diseaseFramingham Heart StudyVentricular geometryConcentric remodelingEccentric hypertrophyHeart StudyNormal geometryCardiovascular disease risk factorsProportional hazards regression modelsLittle prognostic informationIncremental prognostic valueApparent cardiovascular diseaseIncident cardiovascular diseaseDisease risk factorsHazards regression models