2019
Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest
Khera R, Tang Y, Link MS, Krumholz HM, Girotra S, Chan PS. Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005429. PMID: 30871337, PMCID: PMC6592630, DOI: 10.1161/circoutcomes.118.005429.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAwards and PrizesFemaleGuideline AdherenceHeart ArrestHospital MortalityHospitalsHumansInpatientsMaleMiddle AgedOutcome and Process Assessment, Health CarePatient DischargePractice Guidelines as TopicPractice Patterns, Physicians'Quality Indicators, Health CareRegistriesResuscitationTime FactorsTime-to-TreatmentTreatment OutcomeUnited StatesYoung AdultConceptsHospital cardiac arrestCardiac arrestRate of survivalSpontaneous circulationIn-Hospital Cardiac ArrestGuidelines-Resuscitation registryCardiac arrest survivalEndotracheal tube placementHigh rateHospital performanceBest tertileGuidelines-ResuscitationNational GetGuideline adherenceOverall survivalBackground HospitalTube placementNational registryChest compressionsResuscitation qualityHospitalHospital recognitionAward statusSurvivalWeak association
2013
Association Between a Hospital’s Quality Performance for In-Hospital Cardiac Arrest and Common Medical Conditions
Chen LM, Nallamothu BK, Krumholz HM, Spertus JA, Tang F, Chan PS. Association Between a Hospital’s Quality Performance for In-Hospital Cardiac Arrest and Common Medical Conditions. Circulation Cardiovascular Quality And Outcomes 2013, 6: 700-707. PMID: 24221831, PMCID: PMC4465597, DOI: 10.1161/circoutcomes.113.000377.Peer-Reviewed Original ResearchConceptsCommon medical conditionsHospital survival rateAcute myocardial infarctionCardiac arrestMedical conditionsSurvival rateInpatient survivalHeart failureMyocardial infarctionMortality rateHospital cardiac arrest registryHospital qualityIn-Hospital Cardiac ArrestRisk-standardized mortality ratesCardiac Arrest RegistryCardiac arrest outcomesCardiac arrest patientsHospital cardiac arrestCardiac arrest survival ratesPublic reportingHospital outcomesArrest patientsHospital CompareArrest outcomesHospitalLong-Term Outcomes in Elderly Survivors of In-Hospital Cardiac Arrest
Chan PS, Nallamothu BK, Krumholz HM, Spertus JA, Li Y, Hammill BG, Curtis LH. Long-Term Outcomes in Elderly Survivors of In-Hospital Cardiac Arrest. New England Journal Of Medicine 2013, 368: 1019-1026. PMID: 23484828, PMCID: PMC3652256, DOI: 10.1056/nejmoa1200657.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestCardiac arrestNeurologic disabilityReadmission ratesElderly survivorsRisk-adjusted ratesNeurologic statusHeart failureIn-Hospital Cardiac ArrestInpatient cardiac arrestsSevere neurologic disabilityDemographic characteristicsLong-term outcomesLong-term survivalYears of ageRate of survivalHospital dischargeOlder patientsYounger patientsWhite patientsBlack patientsTerm outcomesNational registryMedicare filesPatients
2012
Trends in Survival after In-Hospital Cardiac Arrest
Girotra S, Nallamothu BK, Spertus JA, Li Y, Krumholz HM, Chan PS. Trends in Survival after In-Hospital Cardiac Arrest. New England Journal Of Medicine 2012, 367: 1912-1920. PMID: 23150959, PMCID: PMC3517894, DOI: 10.1056/nejmoa1109148.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestPulseless electrical activityCardiac arrestRisk-adjusted ratesNeurologic disabilityIn-Hospital Cardiac ArrestAcute resuscitation survivalGuidelines-Resuscitation registrySignificant neurologic disabilityQuality improvement registryPulseless ventricular tachycardiaElectrical activityInitial rhythmNeurologic outcomePostresuscitation careAcute resuscitationNeurologic functionSurvival improvementPostresuscitation survivalResuscitation careVentricular tachycardiaRhythm groupVentricular fibrillationMultivariable regressionSurvivalA Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest
Chan PS, Spertus JA, Krumholz HM, Berg RA, Li Y, Sasson C, Nallamothu BK, Investigators F. A Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest. JAMA Internal Medicine 2012, 172: 947-953. PMID: 22641228, PMCID: PMC3517176, DOI: 10.1001/archinternmed.2012.2050.Peer-Reviewed Original ResearchConceptsFavorable neurological survivalHospital cardiac arrestNeurological survivalCardiac arrestNeurological statusDerivation cohortValidation cohortInitial cardiac arrest rhythmIn-Hospital Cardiac ArrestBaseline neurological statusFavorable neurological statusGuidelines-Resuscitation registryCardiac arrest rhythmSevere neurological deficitsPulseless ventricular tachycardiaMultivariate logistic regressionSimple prediction toolRenal insufficiencyArrest rhythmNeurological deficitsHepatic insufficiencyMechanical ventilationMalignant diseaseVentricular tachycardiaInitial survivors
2010
Automated External Defibrillators and Survival After In-Hospital Cardiac Arrest
Chan PS, Krumholz HM, Spertus JA, Jones PG, Cram P, Berg RA, Peberdy MA, Nadkarni V, Mancini ME, Nallamothu BK, Investigators F. Automated External Defibrillators and Survival After In-Hospital Cardiac Arrest. JAMA 2010, 304: 2129-2136. PMID: 21078809, PMCID: PMC3587791, DOI: 10.1001/jama.2010.1576.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestCardiac arrestAED useHospital dischargeHospitalized patientsShockable rhythmNonshockable rhythmsIn-Hospital Cardiac ArrestMultivariable hierarchical regressionGeneral hospital wardsEntire study populationExternal defibrillatorsPropensity score analysisUse of AEDsCohort studyImproved survivalPatient factorsStudy populationMAIN OUTCOMEPatientsHospital wardsUS hospitalsHospital sitesHospital unitsAEDs
2009
Racial Differences in Survival After In-Hospital Cardiac Arrest
Chan PS, Nichol G, Krumholz HM, Spertus JA, Jones PG, Peterson ED, Rathore SS, Nallamothu BK, Investigators F. Racial Differences in Survival After In-Hospital Cardiac Arrest. JAMA 2009, 302: 1195-1201. PMID: 19755698, PMCID: PMC2795316, DOI: 10.1001/jama.2009.1340.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestCardiac arrestBlack patientsWhite patientsSuccessful resuscitationPostresuscitation survivalRacial differencesHospital sitesIn-Hospital Cardiac ArrestLower ratesPulseless ventricular tachycardiaRate of survivalCohort studyHospital dischargePatient characteristicsClinical factorsImmediate resuscitationPostresuscitation periodNational registryVentricular tachycardiaHospital CenterVentricular fibrillationCardiopulmonary resuscitationAdditional adjustmentPatientsHospital Variation in Time to Defibrillation After In-Hospital Cardiac Arrest
Chan PS, Nichol G, Krumholz HM, Spertus JA, Nallamothu BK. Hospital Variation in Time to Defibrillation After In-Hospital Cardiac Arrest. JAMA Internal Medicine 2009, 169: 1265-1273. PMID: 19636027, DOI: 10.1001/archinternmed.2009.196.Peer-Reviewed Original ResearchConceptsCardiac arrestHospital factorsHospital variationIn-Hospital Cardiac ArrestHospital-level effectsHospital cardiac arrestWorse survivalImproved survivalPatient factorsAdult inpatientsHospital predictorsNational registryHospital ratesCardiopulmonary resuscitationGreater oddsIdentical covariatesDefibrillation delaysHospitalDefibrillationDefibrillation timeSurvivalArrestWide variationPatientsInpatients
2008
Delayed Time to Defibrillation after In-Hospital Cardiac Arrest
S. C, M. K, Graham N, K. N, Investigators T. Delayed Time to Defibrillation after In-Hospital Cardiac Arrest. New England Journal Of Medicine 2008, 358: 9-17. PMID: 18172170, DOI: 10.1056/nejmoa0706467.Peer-Reviewed Original ResearchMeSH KeywordsAgedComorbidityElectric CountershockFemaleHeart ArrestHeart FailureHospital Bed CapacityHospital MortalityHospitalizationHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionRetrospective StudiesSurvival AnalysisTachycardia, VentricularTime FactorsVentricular FibrillationConceptsHospital cardiac arrestCardiac arrestHospital dischargeIn-Hospital Cardiac ArrestOverall median timePulseless ventricular tachycardiaMultivariable logistic regressionLower ratesMedian timeVentricular arrhythmiasBlack raceHospital characteristicsNational registryVentricular tachycardiaCardiopulmonary resuscitationExpert guidelinesVentricular fibrillationHospital unitsLogistic regressionPatientsDefibrillationSurvivalArrestHospitalMinutes of delay