2001
Depressive symptoms and risk of functional decline and death in patients with heart failure
Vaccarino V, Kasl S, Abramson J, Krumholz H. Depressive symptoms and risk of functional decline and death in patients with heart failure. Journal Of The American College Of Cardiology 2001, 38: 199-205. PMID: 11451275, DOI: 10.1016/s0735-1097(01)01334-1.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart failureDepressive symptomsFunctional declineCombined end pointDecompensated heart failureBaseline functional statusNegative prognostic factorGeriatric Depression ScaleYears of ageIntermediate riskHospital admissionPrognostic factorsPoor outcomePoor prognosisFunctional statusMedical historyHeart diseaseRisk factorsClinical severityDepression ScaleDaily livingHigh riskPatientsMultivariate analysis
1999
Sex-Based Differences in Early Mortality after Myocardial Infarction
Vaccarino V, Parsons L, Every N, Barron H, Krumholz H. Sex-Based Differences in Early Mortality after Myocardial Infarction. New England Journal Of Medicine 1999, 341: 217-225. PMID: 10413733, DOI: 10.1056/nejm199907223410401.Peer-Reviewed Original ResearchConceptsMyocardial infarctionYears of ageMortality rateSex-based differencesYoung womenMyocardial Infarction 2Odds of deathOverall mortality rateRisk of deathShort-term mortalityHigh-risk groupLogistic regression analysisHigh mortality ratePrognostic factorsEarly mortalityEarly managementMedical historyNational registryClinical severityHigh riskOlder womenInfarctionPatientsHospitalizationWomen
1998
Sex Differences in Mortality After Myocardial Infarction: Evidence for a Sex-Age Interaction
Vaccarino V, Horwitz RI, Meehan TP, Petrillo MK, Radford MJ, Krumholz HM. Sex Differences in Mortality After Myocardial Infarction: Evidence for a Sex-Age Interaction. JAMA Internal Medicine 1998, 158: 2054-2062. PMID: 9778206, DOI: 10.1001/archinte.158.18.2054.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMortality rateAge groupsSex-age interactionOlder womenHigh mortalityHigher hospital mortality rateSex differencesAge group 75 yearsHospital mortality rateRetrospective cohort studyProcess of careYounger age groupsSame age groupHospital deathOlder patientsCohort studyConsecutive patientsPatient ageComorbid conditionsHospital characteristicsClinical severityMedical recordsConnecticut hospitalsHigher oddsPrognostic Importance of Emotional Support for Elderly Patients Hospitalized With Heart Failure
Krumholz H, Butler J, Miller J, Vaccarino V, Williams C, Mendes de Leon C, Seeman T, Kasl S, Berkman L. Prognostic Importance of Emotional Support for Elderly Patients Hospitalized With Heart Failure. Circulation 1998, 97: 958-964. PMID: 9529263, DOI: 10.1161/01.cir.97.10.958.Peer-Reviewed Original ResearchConceptsNonfatal cardiovascular eventsClinical heart failureHeart failureElderly patientsCardiovascular eventsPrognostic importanceNonfatal cardiovascular outcomesCoronary artery diseaseEmotional supportCommunity-based studyCardiovascular outcomesArtery diseaseIndependent predictorsUnadjusted analysesFunctional statusMedical recordsClinical severityOdds ratioEpidemiologic studiesHigh riskPatientsPsychosocial supportEstablished PopulationsAdmissionDemographic factors
1997
Functional Disability Before Myocardial Infarction in the Elderly as a Determinant of Infarction Severity and Postinfarction Mortality
Vaccarino V, Berkman LF, Mendes de Leon CF, Seeman TE, Horwitz RI, Krumholz HM. Functional Disability Before Myocardial Infarction in the Elderly as a Determinant of Infarction Severity and Postinfarction Mortality. JAMA Internal Medicine 1997, 157: 2196-2204. PMID: 9342996, DOI: 10.1001/archinte.1997.00440400046006.Peer-Reviewed Original ResearchConceptsMyocardial infarctionClinical severityFunctional disabilityElderly patientsDaily livingHigh mortalityAcute myocardial infarctionHigher clinical severityMore comorbiditiesPostinfarction mortalityHospital arrivalMI severityInfarction severityHospital treatmentHigh comorbidityRelative riskOutcome measuresCommon conditionPatientsTreatment interventionsMortalityOlder ageSeverity characteristicsSeverityConfidence intervals
1996
Sex Differences in Survival After Myocardial Infarction in Older Adults: A Community‐Based Approach
Vaccarino V, Krumholz H, de Leon C, Holford T, Seeman T, Horwitz R, Berkman L. Sex Differences in Survival After Myocardial Infarction in Older Adults: A Community‐Based Approach. Journal Of The American Geriatrics Society 1996, 44: 1174-1182. PMID: 8855995, DOI: 10.1111/j.1532-5415.1996.tb01366.x.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMultivariable adjustmentClinical severityRelative riskPsychosocial factorsOlder individualsProspective cohort studyMain outcome measuresDemographic factorsSex differencesHospital complicationsCause mortalityLate mortalityClinical characteristicsCohort studyCT cohortHospital admissionOverall mortalityEarly mortalityElderly ProgramMean agePhysical functionFunctional statusMedical recordsOutcome measures