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Michael Schilsky, MD

Professor of Medicine; Medical Director, Adult Liver Transplant, Yale New Haven Transplantation Center

Contact Information

Michael Schilsky, MD

Mailing Address

  • Yale School of Medicine

    Department of Medicine (Digestive Diseases), PO Box 208019

    New Haven, CT 06520-8019

    United States

Research Summary

I am an investigator in clinical trials for patients with Wilson disease and advanced liver disease. My research focus in on the development and validation of biomarkers for copper metabolism and Wilson disease and advancing therapeutics for disorders of copper metabolism.

Extensive Research Description

I am an investigator in clinical trials for patients with Wilson disease, including the testing of once daily use of trientine for maintenance therapy, study of the novel agent WTX 101 (choline-tetrathiomolybdate), a head-to-head trial of trientine tetrahydrochloride and D-penicillamine for Wilson disease, studies on bioavailable (non-ceruloplasmin bound) copper and gene therapy for Wilson disease. I am also the lead and organizing investigator for the multicenter multinational registry for Wilson disease based out of Yale University.


Coauthors

Research Interests

Copper; Liver Transplantation; Liver Failure, Acute

Selected Publications

Clinical Trials

ConditionsStudy Title
Diseases of the Endocrine System; Genetics - AdultA Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease (GATEWAY)
Diseases of the Digestive System - Liver; Diseases of the Eye; Diseases of the Nervous SystemWilson Disease Registry
Hepatitis; HIV/AIDS; Immune System; Infectious DiseasesScreening In Anticipation of Future Research