Poynter Lecture Healthcare for Every Body – Best Practices for Caring for Higher Weight Patients
April 04, 2024April 2, 2024
Poynter Lecture
Healthcare for Every Body – Best Practices for Caring for Higher Weight Patients
Sponsored by the Program fro Humanities in Medicine
The Anlyan Center Auditorium
Ragen Chastain
Speaker, writer, researcher, Board Certified Patient Advocate, multi-certified health and fitness professional, and thought leader in weight science, weight stigma, health, and healthcare.
Information
- ID
- 11541
- To Cite
- DCA Citation Guide
Transcript
- 00:00OK. Oh, there you are.
- 00:02OK. Hi, everybody.
- 00:03Welcome. I'm Anna Reisman,
- 00:05director of the Program for
- 00:06Humanities and Medicine and
- 00:08very pleased to be here with you
- 00:10for this point to lecture. Healthcare
- 00:12for everybody, Everybody.
- 00:13Best practices for caring for higher
- 00:16weight patients Featuring Reagan Chastain.
- 00:19And this talk is happening.
- 00:22Thanks to medical student Chinya Jelly.
- 00:28And so I will introduce Chinya and then
- 00:30turn it over to Chinya to introduce
- 00:33Reagan and to lead the rest of the hour.
- 00:37So Chinya is a fourth year
- 00:38medical student here at Yale.
- 00:40Her research and career interests include
- 00:42HealthEquity and Health Policy.
- 00:44Through her participation in many
- 00:46extracurricular activities, she acts
- 00:47as an advocate for medical trainees
- 00:49and patients from backgrounds
- 00:51underrepresented in medicine.
- 00:52She recently matched into the
- 00:54Family Medicine Residency program
- 00:56at the University of Pennsylvania.
- 00:58Thank you, Jing.
- 01:05Hi, everyone. Thank you so much for coming.
- 01:07Just gonna adjust this mic. Yeah.
- 01:10So I now have the honor of introducing
- 01:13our speaker, Reagan Chastain.
- 01:15She's got many accolades,
- 01:16and I'm just trying to go
- 01:18through as many as possible.
- 01:19Reagan Chastain is a speaker,
- 01:21writer, researcher,
- 01:22board certified patient advocate,
- 01:25multi certified health
- 01:26and fitness professional,
- 01:27and thought leader in weight science,
- 01:29weight stigma, health and healthcare.
- 01:32Utilizing her background in research,
- 01:33methods and statistics,
- 01:35Reagan has brought her signature mix
- 01:37of humor and hard facts to healthcare,
- 01:39corporate,
- 01:39conference and college audiences from
- 01:42Kaiser Permanente and Nationwide
- 01:44Children's Hospital to Amazon and Google,
- 01:47to Dartmouth, Caltech,
- 01:49and ICAA.
- 01:50Author of the Weight and Healthcare
- 01:53Newsletter co-author of Haes
- 01:55Health sheets and editor of the
- 01:58anthology The Politics of Science,
- 02:00Reagan is frequently featured
- 02:01as an expert in print, radio,
- 02:04television and documentary film.
- 02:06In her free time,
- 02:07Reagan is a national dance champion,
- 02:09Tri athlete and marathoner
- 02:11who holds the Guinness World
- 02:13Record for the heaviest
- 02:14woman to complete a marathon.
- 02:16Reagan lives in Oregon
- 02:18with her fiance Julianne,
- 02:19and a rotating cast of foster dogs.
- 02:22Please give her a warm welcome.
- 02:25Thank you so much.
- 02:28Thank you so much for having me.
- 02:29The worst part about being a
- 02:31professional speaker is hearing
- 02:32your bio read over and over again.
- 02:33So thank you so much and thanks
- 02:35for all the work to bring me here.
- 02:37These things are no small feat to put
- 02:39together and I hugely appreciate it.
- 02:41So we're gonna talk a bit
- 02:42about healthcare for everybody.
- 02:43A couple things to start off with.
- 02:45First of all, I'm not a doctor.
- 02:46I don't play one on TV.
- 02:47My area of expertise is the research.
- 02:49I've been researching the intersections
- 02:50of weight science, weight stigma,
- 02:52and healthcare for about 20 years.
- 02:54And so my goal is to bring my research
- 02:56knowledge to help you in whatever you do,
- 02:58including if you're a practitioner,
- 03:01I may talk about things that are
- 03:03different than what you have learned,
- 03:06than what you have taught other people.
- 03:09And so in the 20 years that
- 03:11I've studied weight science,
- 03:12I can tell you I've had all
- 03:13the feelings right?
- 03:14Anger, defensiveness, denial.
- 03:15And so if that comes up,
- 03:18I just want to say that's incredibly valid.
- 03:20And also if it does, Ioffer that
- 03:22as an as an invitation to explore,
- 03:25right, to dig deeper.
- 03:26And I'm happy to help with that.
- 03:28That's my e-mail,
- 03:30reagan@wadeandhealthcare.com.
- 03:30You're welcome to e-mail me anytime.
- 03:31I pretty much live to talk about this stuff.
- 03:34I also want to say that when I talk
- 03:35about mistakes that are made around
- 03:37weight science and weight Sigma healthcare,
- 03:39I have typically made each and every
- 03:41one of these mistakes personally.
- 03:43And I don't think that people are making
- 03:45these mistakes typically out of malice.
- 03:46But I do think that there's a lot
- 03:48of misinformation that floats around
- 03:49and I do think that we've sort of
- 03:51built a paradigm on research that
- 03:53doesn't necessarily support it.
- 03:54And so that's what I'll talk about today.
- 03:56Most of my work,
- 03:57I think a lot about the Galileo
- 03:58story and we all know the whole,
- 04:00like, figured out the earth,
- 04:01revolved around the sun,
- 04:02put under house arrest,
- 04:04forced recant, terrible.
- 04:04The part of that story that most
- 04:07interests me is that Galileo's
- 04:08contemporaries are said to have
- 04:10refused to look through the telescope.
- 04:12So it's not that they were saying this
- 04:14telescope is poorly made or your math is off.
- 04:16They simply wouldn't look.
- 04:17And so a lot of my work is just asking
- 04:20people to look through the telescope.
- 04:33Got it? Well, we can click this way.
- 04:37There we go. OK. All right.
- 04:38I want to start about,
- 04:39start off talking about language.
- 04:40And I also want to say this is going to
- 04:41be about a 20 minute talk and then we're
- 04:43going to do an interview and AQ and A.
- 04:44And so this talk can go from
- 04:4620 minutes to four hours.
- 04:47So I'm really like condensing
- 04:48down to the high point.
- 04:49So again, there's a lot more to unpack
- 04:51here and I welcome you to reach out to
- 04:53me if you'd like to ever discuss this.
- 04:55So obese and overweight.
- 04:57These were terms that were literally
- 04:59created for the express purpose of
- 05:01pathologizing bodies based on shared
- 05:03size rather than shared symptomatology
- 05:05or cardio metabolic profile.
- 05:06The origin of pathologizing
- 05:08bodies based on size,
- 05:09the origin of weight stigma in general,
- 05:11the origin of the body
- 05:12mass index in specific.
- 05:13These things are rooted in an inextricable
- 05:16from racism and anti blackness.
- 05:18And I that's not my scholarship,
- 05:20that's what I've learned.
- 05:21And I absolutely recommend
- 05:23reading Sabrina's Strings,
- 05:23Fearing the Black Body and Deshawn
- 05:25Harrison's Belly of the Beast to learn
- 05:27more about how not only are these
- 05:29things rooted in racism and anti blackness,
- 05:31but they continue to disproportionately
- 05:33impact those communities today.
- 05:35So the impact of this idea of
- 05:37pathologizing higher weight bodies has
- 05:38been a tremendous amount of profit to
- 05:40the weight loss industry who have been
- 05:42the primary architects of this paradigm.
- 05:43A lot of stigma and oppression to
- 05:45the people in these classifications,
- 05:47a lot of separation between higher
- 05:49weight people and health and healthcare
- 05:51and healthcare practitioners,
- 05:53and basically no decrease in the
- 05:54number of higher weight people.
- 05:55In fact,
- 05:56there's been a consistent increase in
- 05:58the number of higher weight people.
- 06:00So then there's person first
- 06:01language and you may have heard
- 06:02this idea as anti stigma language,
- 06:04the idea that saying a person
- 06:05with obesity or a person with
- 06:07overweight is less stigmatizing.
- 06:09And the first thing I want you to
- 06:11know is that this did not come from
- 06:13weight neutral health community,
- 06:14it did not come from bad activism community.
- 06:15This again,
- 06:16came from the weight loss industry and
- 06:19through the advocacy groups that they fund.
- 06:22And so this the problem
- 06:23with person first language,
- 06:24besides the fact that it makes
- 06:26us sort of unwitting marketers
- 06:27for the weight loss industry,
- 06:28is that it's actually more stigmatizing
- 06:30because it means we talk about
- 06:31higher weight bodies differently
- 06:32than we talk about any other body.
- 06:34We're never like,
- 06:35oh thank goodness my friend
- 06:36with tallness is here.
- 06:37Now we can finally change that light bulb,
- 06:39right?
- 06:39Or my friend with blondness is
- 06:40going to sit next to me or oh,
- 06:41that man with thinness getting on the bus.
- 06:43I believe I know him right.
- 06:44That's not how we talk about bodies.
- 06:46So when we suggest that higher
- 06:48weight bodies that simply accurately
- 06:49naming them is so stigmatizing
- 06:51that it requires A
- 06:52semantic work around,
- 06:53that in fact is stigma.
- 06:57And so Person first language is roundly
- 06:59rejected by both weight neutral health
- 07:01community and fed activism community,
- 07:03anti stigma language.
- 07:04What we're looking for are terms that
- 07:06accurately describe these bodies without
- 07:08medicalizing or pathologizing them,
- 07:10and that we're not used as a taunt or
- 07:11slur in a way that could be triggering.
- 07:13And so those can be terms like
- 07:15higher weight people of size,
- 07:16larger bodies then we have fat.
- 07:19Fat is my preferred personal
- 07:21descriptor for a lot of reasons,
- 07:22but fat is a reclaiming term with all of
- 07:24the complexities that come with that.
- 07:26So there are people who could be defined
- 07:28as fat who reject that term completely,
- 07:30and that's totally valid.
- 07:31I like it because it's one of
- 07:33the ways I tell my bullies.
- 07:34They can't have my lunch money anymore,
- 07:36right? You can't offend me by
- 07:38accurately describing my body.
- 07:39And also, again,
- 07:40it doesn't medicalize or pathologize my body.
- 07:42Now, I'm not suggesting that
- 07:43you chart people as fat, right?
- 07:45But what I am saying is if someone
- 07:47describes themselves as fat in
- 07:48a neutral or a positive way,
- 07:50then we must never,
- 07:51never correct them.
- 07:52You're not fat.
- 07:53Don't call yourself fat because
- 07:54they in fact are fat no matter
- 07:56what we're calling them.
- 07:57So suggesting that again,
- 07:59accurately describing yourself as
- 08:01somehow offensive again is stigma.
- 08:03And this is an issue that happens
- 08:04in a lot of weight stigma research
- 08:06where that weight stigma research is
- 08:08actually rooted in anti fatness, right.
- 08:10So what We'll start the obesity
- 08:13epidemic continues unabated.
- 08:14You know there will be X number
- 08:15of obese people soon.
- 08:16Anyway,
- 08:17let's talk about not stigmatizing them,
- 08:19right.
- 08:19So it comes from a point of view of
- 08:20like we don't want to stigmatize fat people,
- 08:22but we definitely want to eradicate
- 08:23them from the earth and make
- 08:25sure no more ever exist.
- 08:26That's not an anti stigma point of view,
- 08:28right?
- 08:29And so all of that gets
- 08:30rooted into this language.
- 08:31So throughout this talk,
- 08:32I'll use higher weight in people's size,
- 08:35larger body and fat interchangeably.
- 08:37I'll use quote obese and quote
- 08:38overweight when I talk about the
- 08:40research that uses those terms.
- 08:41And I will not
- 08:41use person first language.
- 08:43So in the 20 years that I've
- 08:45been studying weight science,
- 08:47there are some commonalities that I
- 08:49want to talk about within the research.
- 08:51The first basic premise error I see
- 08:52in a tremendous amount of the research
- 08:54is this idea that will have higher
- 08:55weight patients experience a health
- 08:57issue more often than thinner patients.
- 08:59Then it must be because they're
- 09:01higher weight and everybody knows
- 09:02from their first day in their
- 09:03first research methods class.
- 09:04This is a correlation causation error.
- 09:06And this is complicated in
- 09:08healthcare research because we
- 09:09use correlation all the time,
- 09:11but it's not responsible to do that without
- 09:14actually investigating confounding variables.
- 09:15What else could be affecting
- 09:18this relationship?
- 09:19And here we have weight, weight stigma,
- 09:21weight cycling and healthcare inequalities,
- 09:23which we'll talk about in a moment.
- 09:25And there's also surveillance
- 09:26bias and testing rate, right?
- 09:28So if higher weight people are,
- 09:30as we find in research,
- 09:31often have their blood pressure
- 09:33taken with A2 small cuff,
- 09:34which gives an artificially elevated reading,
- 09:36and then we say, wow,
- 09:37those people have a lot of hypertension.
- 09:39That's an example of surveillance
- 09:40or testing bias.
- 09:41If we test higher weight people
- 09:43early and often for type 2 diabetes
- 09:44and we don't test thin patients,
- 09:46that's an example of surveillance
- 09:48or testing bias.
- 09:49The second basic premise error is OK.
- 09:50Well,
- 09:51if higher weight patients experience
- 09:52a health condition more often,
- 09:54or if a healthcare intervention
- 09:55is less effective for them,
- 09:56then the solution is to make
- 09:58them into thinner patients.
- 09:59So using weight as a proxy for
- 10:01health becomes problematic really
- 10:02quickly because no matter what
- 10:04definition someone's trying to use,
- 10:05whether it's BMI, waist,
- 10:07circumference, you know,
- 10:09percentage of adiposity,
- 10:11we still have the same issue,
- 10:12which is that you can have people
- 10:14who have those exact same traits with
- 10:16vastly different health statuses and
- 10:18symptomatology and cardio metabolic profiles.
- 10:21You can have people with vastly
- 10:23different weight, BMI,
- 10:24waist, circumference,
- 10:25etcetera,
- 10:26with the exact same health status and
- 10:29symptomatology and cardio metabolic profile.
- 10:31Also,
- 10:31people experience weight changes without
- 10:33health changes and they experience
- 10:34health changes without weight changes.
- 10:36And So what this becomes is
- 10:37sort of like saying,
- 10:38well,
- 10:38we know that CIS male pattern
- 10:40baldness is incredibly highly
- 10:41correlated with cardiac incidents.
- 10:43So the obvious solution is to
- 10:44get these folks to grow hair.
- 10:46It's the obvious difference.
- 10:47Like we've got to have a war on baldness.
- 10:49We've got to fix this,
- 10:50and that's what happens.
- 10:52It sounds ridiculous,
- 10:53and it is ridiculous,
- 10:53but in many ways,
- 10:54when you dig into weight signs,
- 10:55this is exactly what is happening.
- 10:59So in looking at those confounding variables,
- 11:01there's often in this weight science
- 11:03research a deep failure to control.
- 11:06So the first is controlling for
- 11:08the effects of weight stigma.
- 11:10Munich found that experiencing
- 11:11weight stigma over time was
- 11:12associated with increased rates of
- 11:14blood pressure and type 2 diabetes.
- 11:18Sutentanol found that perceived weight
- 11:19discrimination was associated with an
- 11:21increase in mortality risk of nearly 60%.
- 11:24And Munich, in a separate study,
- 11:25found that the difference between
- 11:27actual and desired body weight was a
- 11:30stronger predictor of physical and mental
- 11:32health than actual body mass index.
- 11:34Right? And typically,
- 11:35weight stigma is often not even mentioned,
- 11:37let alone controlled for in studies
- 11:39that claim to find a relationship
- 11:41between weight and health issues.
- 11:44Then we've got weight cycling.
- 11:46So Gaysern and Gotti found that
- 11:48the risks associated with weight
- 11:49cycling are very much the same as
- 11:51those associated with quote obesity,
- 11:53bacon and AD for more found weight
- 11:55cycling results in increased inflammation,
- 11:57which in turn is known to
- 11:58increase the risk for many,
- 11:59quote UN quote obesity associated diseases.
- 12:01And it's important to understand that
- 12:03when we talk about weight related or
- 12:05quote obesity associated diseases,
- 12:07we're talking about diseases that
- 12:08people of all sizes have that get called
- 12:11weight related or obesity associated
- 12:13when higher weight people have them.
- 12:15Research also indicates that weight
- 12:17fluctuation or weight cycling is associated
- 12:19with poor cardiovascular outcomes and
- 12:21increased overall mortality risk.
- 12:22And in fact,
- 12:23Bacon and Aftermore found that weight
- 12:25cycling could account for all of the
- 12:27excess mortality that was associated with,
- 12:29quote, obesity in both the
- 12:30Framingham and the Enhanes.
- 12:34And this is important because about a
- 12:36century of research from Stunkred ET
- 12:37al in 1959 that actually looked at the
- 12:39previous 30 years of research to at
- 12:41least Gazer and Angadi in 2021 found
- 12:43that the most common outcome by far
- 12:46of intentional weight loss attempts is
- 12:48short term weight loss and then long
- 12:50term weight regain which is weight cycling.
- 12:53So for about 100 years we've been
- 12:55prescribing these healthcare interventions
- 12:57right where the majority of people lose
- 12:59weight short term and and regain it.
- 13:01So we've been prescribing weight
- 13:04cycling essentially and then finally
- 13:06we have lack of access to ethical
- 13:07evidence based healthcare.
- 13:09And so here we can talk about practitioner
- 13:11bias and that is of course both
- 13:13implicit and explicit is an issue.
- 13:14But it goes beyond that.
- 13:15Most research doesn't include
- 13:17higher weight people.
- 13:19I was just speaking at a conference
- 13:21for anesthesiologists and and looking
- 13:22at like 30 years of anesthesia
- 13:24research repeatedly.
- 13:25They would create guidelines and the
- 13:26guidelines would start by saying,
- 13:28you know,
- 13:28guidelines for higher weight people.
- 13:30And they would start by saying,
- 13:31well, we know that pharmacokinetics
- 13:33and pharmacodynamics are different
- 13:34for higher weight people,
- 13:35but we're not sure how because they're
- 13:37typically excluded from drug trials.
- 13:38Anyway,
- 13:39here's some guidelines, right?
- 13:41And so instead of saying,
- 13:42dear God,
- 13:43we need to do studies that actually include
- 13:45higher weight people so that we know
- 13:47how this medication works in their bodies,
- 13:49they simply sort of shrug it off.
- 13:51And this is an example of both weight
- 13:53stigma and the healthcare inequality,
- 13:55the outcomes of which will often be
- 13:58blamed on higher weight people's bodies.
- 14:00And then there's accommodation,
- 14:02right?
- 14:02Simply a chair in the waiting
- 14:04room that someone can sit in the
- 14:05correct size blood pressure cup,
- 14:06A correct size gown,
- 14:08a correct size MRI until healthcare actually
- 14:10accommodates people of higher weights,
- 14:12Until there's research so that
- 14:14the tools and best practices and
- 14:16pharmacotherapies that are developed
- 14:17through research are actually
- 14:19developed for higher weight people,
- 14:21we cannot possibly have equality.
- 14:23And blaming higher weight people
- 14:25for healthcare's failings is
- 14:26not just weight stigma,
- 14:28but it also then perpetuates weight stigma.
- 14:32So also there's an underlying tenant of
- 14:34a lot of care of higher weight people,
- 14:36including in the way that the FDA
- 14:38approves weight loss interventions,
- 14:39that it's worth risking higher weight
- 14:41people's lives and quality of life
- 14:42and attempts to make them thin.
- 14:43And it's particularly important to
- 14:45know that that's coming from this
- 14:47research that I was just talking about,
- 14:49where there's no control for weight stigma,
- 14:50weight cycling or healthcare inequalities,
- 14:53right?
- 14:53Where there's just a pile of
- 14:55research that correlates being
- 14:56higher weight with health issues.
- 14:57And then the conclusion is Oh well
- 14:59obviously it's so dangerous to be
- 15:01higher weight it's worth risking
- 15:02higher weight people's lives and
- 15:04quality of life to make them thin.
- 15:06So the bottom line here is that
- 15:07what are sometimes called weight
- 15:09related or quote obesity related
- 15:11conditions again might
- 15:12actually be weight stigma related
- 15:14conditions and or weight cycling
- 15:16related conditions and or healthcare
- 15:18inequality related conditions.
- 15:20And until these are controlled
- 15:21for we cannot possibly know or
- 15:23understand the relationship between
- 15:24body size or adiposity and health.
- 15:28So what we have currently is a
- 15:30blame game where healthcare and
- 15:32the weight loss industry create and
- 15:35perpetuate weight stigma and weight
- 15:37cycling and care inequalities.
- 15:39And then research blames the
- 15:41negative outcomes of that on
- 15:43higher weight people's bodies.
- 15:44And then those negative outcomes
- 15:46are used to justify additional
- 15:47weight stigma and weight cycling
- 15:49and healthcare inequalities.
- 15:50And we're caught in this loop.
- 15:52And again, I don't think people
- 15:53are doing this on purpose.
- 15:55I think often it's a matter of
- 15:58paradigm entrenchment, right?
- 15:59Not looking through the telescope,
- 16:00being so sure that this must be the way
- 16:02it is that we don't ask the questions.
- 16:06And so then I want to talk real quickly
- 16:08about one claim that's very common.
- 16:09We hear, OK, 5 to 10% weight loss leads
- 16:12to clinically meaningful health benefits.
- 16:14And the first thing I want you to know is
- 16:16that that number came through attrition.
- 16:17It started with the metropolitan
- 16:19life tight weight tables where there
- 16:21was very specific if you are this,
- 16:23this height and this frame,
- 16:24you should weigh this amount.
- 16:26But they couldn't get people to lose
- 16:28anywhere near that amount of weight.
- 16:29So they moved to 20%,
- 16:30not through clinical trials,
- 16:31but because it was a round
- 16:33Number and it seemed memorable.
- 16:35But they couldn't get people to lose 20%.
- 16:36So they went to 10%, then five to 10.
- 16:38And recently I've seen three to five,
- 16:40an amount of weight I could lose
- 16:42with a haircut and a loofah, right,
- 16:44But always attaching this clinically
- 16:46meaningful health benefits phrase to the end.
- 16:49And so Man and Tomiama, I'm sorry,
- 16:51Tomiama, Osterman,
- 16:52Man in 2013 tested this to see,
- 16:54do these small amounts of weight
- 16:56loss actually create clinically
- 16:57meaningful health benefits?
- 16:59And what they found was
- 17:00in correlational analysis,
- 17:01we uncovered no clear relationship
- 17:03between weight loss and health
- 17:04outcomes related to hypertension,
- 17:06diabetes or cholesterol,
- 17:07calling into question whether weight
- 17:09change per SE had any causal role
- 17:12in the few effects of the diets.
- 17:14Increased exercise, healthier eating,
- 17:15engagement with the healthcare
- 17:16system and social support may
- 17:18have played a role instead.
- 17:19And So what we might actually
- 17:20be seeing is that people,
- 17:21when they engage in these
- 17:23weight loss interventions,
- 17:24they make behavior changes.
- 17:25They experience health changes
- 17:27and they experience typically
- 17:29temporary weight changes.
- 17:31And even though the weight changes
- 17:33are both small and simultaneous,
- 17:34we tend to credit them
- 17:35for the health changes,
- 17:36ignoring the behavior changes
- 17:37that preceded the health changes.
- 17:41And this is supported when we
- 17:43look at research like Klein ET al.
- 17:45So they looked at OK will large volume
- 17:48abdominal liposuction create these
- 17:49same improvements and they found that
- 17:51in fact they did not that large volume
- 17:54abdominal liposuction basically fat
- 17:56loss without behavior change does not
- 17:59significantly improve obesity associated
- 18:01metabolic abnormalities and again
- 18:03caveat on the quote obesity associated.
- 18:06And then we have this body of research
- 18:09that looks at retrospective studies.
- 18:11So we'll start with the way at all
- 18:14they looked at 25,714 adults, CIS men.
- 18:17Now in this study,
- 18:18as in almost every study that
- 18:19I'll talk about,
- 18:20there is no trans and non binary
- 18:22representation and there is an under
- 18:24representation of people of color.
- 18:25And that is a consistent issue that
- 18:26should never have happened and certainly
- 18:28should have been solved before now.
- 18:30But we see this.
- 18:31So they looked at the relationship
- 18:33between relative risk of all
- 18:34'cause mortality and body size.
- 18:36And if you look at these Gray bars,
- 18:38these are quote UN quote normal weight,
- 18:39quote UN quote overweight and
- 18:41quote UN quote obese CIS men who
- 18:43were not participating in fitness.
- 18:44And we can see the rise in all
- 18:46'cause mortality as body size rises.
- 18:47Now we cannot say that is caused
- 18:50by body size,
- 18:51again because of the possible confounders,
- 18:52but we do see that it's there.
- 18:54These red bars are CIS men who
- 18:56are participating in 170 minutes
- 18:57of movement a week.
- 18:58And what we see here is that their
- 19:01relative risk of all 'cause mortality was
- 19:04essentially the same regardless of size.
- 19:06Matheson and all took this further.
- 19:08They looked at 11,761 CIS men and women
- 19:11and they looked at 4 healthy habits,
- 19:135 or more servings of fruits and vegetables,
- 19:15exercise more than 12 * a month
- 19:16alcohol up to 1 drink a day for
- 19:18CIS women and two drinks a day
- 19:20for CIS men and not smoking.
- 19:22And so here we have their graph.
- 19:23Y axis is the health hazard ratio.
- 19:25X axis is the number of those four healthy
- 19:27habits people were participating in,
- 19:28from none of them to all four.
- 19:32And then on top of each of those numbers are
- 19:34three bars for quote UN quote normal weight,
- 19:36quote UN quote overweight,
- 19:37and quote UN quote obese.
- 19:38We can see when people were
- 19:40participating in none of the habits,
- 19:41there was a pretty big striation
- 19:43among health hazard ratio.
- 19:44Once again,
- 19:44we cannot say this is caused by body size,
- 19:46but we do see that it's there.
- 19:48When people participated in just one of
- 19:50those habits that compressed significantly
- 19:53for those participating in all four,
- 19:54they had essentially the same health
- 19:56hazard ratio regardless of size.
- 19:58And this is what we see over
- 19:59and over and over again.
- 20:00If we actually take behaviors into account,
- 20:03they may well be a better predictor
- 20:04of current and future health than
- 20:06his body size or weight loss.
- 20:07So Gazer and Gaudi is the
- 20:09last study we looked
- 20:09at 2021. They looked at 225 studies,
- 20:12systematic reviews and meta analysis.
- 20:15And they were looking at the
- 20:16relationship between physical activity,
- 20:17cardiorespiratory fitness and health.
- 20:18And what they found was the mortality
- 20:20risk that gets associated with
- 20:21quote obesity is largely attenuated
- 20:23or eliminated by moderate to
- 20:24high levels of cardiorespiratory
- 20:26fitness or physical activity.
- 20:27They found most cardio metabolic risk
- 20:29factors that are associated with, quote,
- 20:31obesity can be improved with exercise
- 20:33training independent of weight loss
- 20:34and by a magnitude similar to that
- 20:36observed with weight loss programs.
- 20:38Which is really important because
- 20:39as we see with weight loss programs,
- 20:40the vast majority of people regain weight
- 20:42and lose cardio metabolic benefits.
- 20:45They found that weight loss,
- 20:46even if it was intentional,
- 20:47was not consistently associated
- 20:49with a lower mortality risk.
- 20:52They found that increases in
- 20:53cardiorespiratory fitness and physical
- 20:54activity are consistently associated
- 20:56with greater reductions in mortality
- 20:57risk than is intentional weight loss.
- 21:01They found, again,
- 21:02weight cycling is associated with
- 21:03numerous adverse health outcomes,
- 21:05including increased mortality.
- 21:06And they posited that adherence to
- 21:08physical activity might improve if
- 21:09healthcare professionals emphasize to
- 21:11their patients the myriad benefits of
- 21:13physical activity and cardiorespiratory
- 21:14fitness in the absence of weight loss.
- 21:16Because what higher weight people are
- 21:18told is exercise makes you lose weight,
- 21:20which makes you healthier.
- 21:22And so people start an exercise
- 21:23program and they either lose a
- 21:24little bit of weight and gain it
- 21:25back or they don't lose weight at
- 21:26all and then they quit because they
- 21:28assume it's not working because
- 21:29they've been misled about the likely
- 21:31outcome and also about the benefits.
- 21:33It's important to understand
- 21:34the benefits of these health
- 21:36supporting behaviors are direct.
- 21:39So then we've got an RCT.
- 21:41So there's not a lot of randomized
- 21:43controlled trials of weight neutral
- 21:46health interventions and a big
- 21:48part of that is that so much of
- 21:49the funding is earmarked only for
- 21:51quote UN quote obesity treatment and
- 21:53prevention which is a huge issue.
- 21:55But Lindo Bacon ET all did a
- 22:00randomized controlled style trial.
- 22:02They looked at weight neutral
- 22:03intervention versus a behavior
- 22:04based weight loss intervention.
- 22:05It was a six month RCT with
- 22:07two years of follow up.
- 22:09At six months,
- 22:1041% of the diet group had quit and only
- 22:128% of the weight neutral group had quit.
- 22:15At two years,
- 22:1650% of both groups returned for evaluation.
- 22:19Among the weight neutral group,
- 22:20they had maintained their weight,
- 22:22improved all outcome variables
- 22:23and sustained the improvements.
- 22:24Over 2 years,
- 22:25the diet group had regained their weight
- 22:28and little improvement was sustained,
- 22:30which is what the previous
- 22:32research would tell us.
- 22:33So what we're talking about
- 22:34here is a change in focus.
- 22:36Instead of focusing on manipulating the
- 22:37weight of fat patients and focusing on
- 22:39trying to figure out how to quote UN quote,
- 22:41treat existing in a higher weight body,
- 22:44we focus on supporting people's health
- 22:45at their current size in research,
- 22:47in tools and equipment,
- 22:49in practitioner training,
- 22:50from compassion and anti stigma
- 22:52to practice right.
- 22:53What do we have?
- 22:54What does the research actually tell
- 22:56us is the best thing for our patients
- 22:57who are higher weight to advocacy,
- 22:59which is advocating for the research
- 23:01We don't have right in advocating
- 23:03for equality in structural bias,
- 23:06including things like chairs and Mr.
- 23:08IS and blood pressure, cuffs and gowns.
- 23:11Best practices and informed consent
- 23:13around weight loss interventions.
- 23:14True informed consent.
- 23:17So best practices,
- 23:18sorry,
- 23:21best practices include weigh in only
- 23:24when medically necessary, right?
- 23:26Rather than routine weigh insurance
- 23:28between no 'cause patient disengagement,
- 23:31allowing patients to decline with no
- 23:33pushback, and considering signage,
- 23:34and absolutely never offering
- 23:35to guess a patient's weight.
- 23:37The first time this happened to me,
- 23:38I was so surprised.
- 23:40I literally said this is not the County Fair.
- 23:42You're not guessing my weight today.
- 23:44And now what I say is either a number is
- 23:46medically relevant or it's guessable.
- 23:47And since you've told me it's guessable,
- 23:49I know it's not medically relevant.
- 23:53Look for inequalities and solve them.
- 23:54In what ways are higher weight people
- 23:56not having the same experience
- 23:58in a space that you're in?
- 24:00Right? Are there chairs that
- 24:01would accommodate folks, sturdy,
- 24:03armless chairs in love seats?
- 24:05Are there gowns?
- 24:05Are there blood pressure cuffs?
- 24:06Is there only one thigh cuff?
- 24:09And so anytime a higher weight patient
- 24:11needs their blood pressure taken,
- 24:12everybody has to run around and try
- 24:14to find that one thigh cuff, right?
- 24:16That's a procurement issue that's
- 24:18pretty pretty easily solved if you're
- 24:20tempted to prescribe weight loss,
- 24:22asking ourselves, OK, well,
- 24:23what would we do for a thin
- 24:25person who has this health issue?
- 24:26And have we tried that for this patient,
- 24:30choosing medications based on
- 24:32therapeutic effects first,
- 24:33not necessarily just weight impact 1st and
- 24:36also making sure to get informed consent.
- 24:39I'm hearing from a lot of patients
- 24:41now who are being told to try the new
- 24:43GLP one agonist weight loss drugs and
- 24:45when they ask about side effects,
- 24:46they're being told, well all drugs
- 24:48have side effects and it's no big deal.
- 24:50That is not an informed consent conversation
- 24:53creating a list of accommodating options.
- 24:55If you know that your facility
- 24:56doesn't have a large bore MRI,
- 24:58find out proactively what facility
- 25:01does and have a list of these things
- 25:03so that instead of just setting
- 25:04the patient out and saying we can't
- 25:05accommodate you saying here's the space,
- 25:09that can't.
- 25:10All right, so I'll finish this up
- 25:11and we'll go to the interview.
- 25:12I just want to say,
- 25:12even if I'm wrong and I have to
- 25:14say that right,
- 25:15every scientist has to say that even if
- 25:18higher weight patients could all become thin,
- 25:20even if by becoming thinner
- 25:21they would all become healthier,
- 25:22higher weight patients would still deserve
- 25:24equal accommodation and access to the world,
- 25:26including healthcare.
- 25:27Fat people have the right to
- 25:29exist without shame, stigma,
- 25:30bullying or oppression.
- 25:31It doesn't matter why they're fat.
- 25:33It doesn't matter if their
- 25:34health impacts of being fat.
- 25:35It doesn't matter if they could
- 25:37or even want to become thinner.
- 25:38The rights to life,
- 25:39liberty,
- 25:39and the pursuit of happiness are
- 25:40not and should not be size dependent.
- 25:44All right, so you're welcome to contact me.
- 25:46You can e-mail me, you can message me,
- 25:48you can find more resources.
- 25:49The Health at Every Size health
- 25:50sheets are weight neutral,
- 25:51diagnosis specific care guides.
- 25:52So you can literally download
- 25:54like Fatty Liver and see OK,
- 25:56what's the weight neutral
- 25:57option for caring for that.
- 25:58There's also a resource in research bank,
- 26:00so if you like me or a mega nerd,
- 26:02that's a good place to kind of dig in.
- 26:04And then Wade and Healthcare is
- 26:05my newsletter where I talk about
- 26:06these things pretty much endlessly.
- 26:07So thank you.
- 26:08I know this is a lot of information fast.
- 26:10Do please feel free to reach out to
- 26:11me with any questions or thoughts.
- 26:13And I'm looking forward to our interview.
- 26:38Can you guys hear me?
- 26:40Fantastic. Yours is working.
- 26:42I think. So. Can you hear me?
- 26:44Perfect. Thank you.
- 26:46So I want to start by saying that that
- 26:48talk was so inspiring and eye opening. I
- 26:51really appreciate it. That's why I was
- 26:53like you guys have to give her a hand.
- 26:54That's amazing. Thank you.
- 26:57And so I have a handful of questions
- 26:59I want to ask you and some of
- 27:00them you already touched on,
- 27:01but I'm going to give you the
- 27:03opportunity to elaborate.
- 27:04Thank you. So first,
- 27:06a topic that is probably
- 27:08on a lot of people's minds,
- 27:10and if it's not,
- 27:11it should be is the GLP one
- 27:15agonist that you mentioned,
- 27:17drugs like Ozempic.
- 27:18Can you talk about how the
- 27:20introduction of those drugs and
- 27:21sort of the frenzy around them has
- 27:23affected higher weight people?
- 27:24Sure. So I think they've really changed
- 27:27the conversation around the idea of
- 27:29weight loss and weight management and
- 27:30I think that's happened prematurely.
- 27:32Sort of a sub specialty of mine is
- 27:34the ways in which the weight loss
- 27:36industry works to influence and
- 27:38manipulate the healthcare industry.
- 27:39And I think there's a lot of that
- 27:41here to go back and just give
- 27:42a little bit of context.
- 27:43So Novo Nordisk and Eli Lilly,
- 27:44who are the two big players right
- 27:46now with the GLP One agonist,
- 27:47though there are more coming.
- 27:49We're also big players in insulin
- 27:51and price gouging on insulin.
- 27:54And they did that through
- 27:55something called shadow pricing,
- 27:56where they look and see.
- 27:57And as their competitor
- 27:58increases their price,
- 27:59they increase their price
- 28:00sometimes within minutes.
- 28:02And that's how the price of
- 28:03insulin went up and up and up.
- 28:04And so as they were forced to
- 28:06bring down the price of insulin,
- 28:07Novo Nordisk CEO said he was going to quote,
- 28:10take a bet on quote obesity.
- 28:13And so when Wagovi was approved,
- 28:15which is the Somali tide,
- 28:17the form of Ozempic,
- 28:19that's for weight loss,
- 28:20they promised their shareholders
- 28:22the fastest ever launch of the
- 28:24drug and they did exactly that.
- 28:25And so there's been a huge marketing
- 28:28push and everything from paid speakers
- 28:31who are doctors and researchers
- 28:33who are putting out research,
- 28:35who are advocating in the papers,
- 28:37often without disclosure,
- 28:38to their own marketing around this,
- 28:40to their advocacy groups that they fund.
- 28:43So there's been a huge push.
- 28:45And the thing about these
- 28:46drugs that's important,
- 28:47first of all,
- 28:48they are Type 2 diabetes drugs
- 28:49with a side effect of weight loss.
- 28:51And so they are dosed and titrated very
- 28:53differently when dosed for type 2 diabetes.
- 28:55The goal is to give the minimum dose to
- 28:57get glycemic management and to minimize
- 29:00side effects windows for weight loss.
- 29:02The goal is to maximize side effects and
- 29:05you can't do that without maximizing
- 29:06all dose dependent side effects.
- 29:08We only have two years of data
- 29:11on these drugs at that dose.
- 29:13For Ozempic until just a year,
- 29:15two years ago the maximum
- 29:17dose was 1 milligram.
- 29:19For the last two years the maximum
- 29:20dose has been 2 milligrams.
- 29:21Well,
- 29:22Govi is 2.4kg,
- 29:25so we've got a bunch of people on
- 29:26a mega dose of a type 2 diabetes
- 29:28drug with only two years of data.
- 29:30We know from their research that
- 29:31when people go off the drug they do
- 29:33regain the weight pretty quickly.
- 29:35But also even their own two year
- 29:36research shows that at the end of two
- 29:38years people who stayed on the drug,
- 29:39their weight is ticking up.
- 29:42Also about 10 to 15% of people
- 29:44don't lose weight on the drug
- 29:45and in the tirzepatide study.
- 29:47So there's a thing that happens
- 29:49in weight science research where
- 29:50words that mean things get new
- 29:52and interesting definitions.
- 29:54So in the tirzepatide study,
- 29:55maintained weight loss meant
- 29:57gained back less than 20%
- 29:59of the weight by the first year, right.
- 30:03So they did a 36 week treatment and then
- 30:05they observed for the next 52 weeks,
- 30:07some people went off, some people
- 30:08stayed on and so maintained weight loss
- 30:10just meant they were regaining slowly,
- 30:12which is a little bit questionable to me.
- 30:15And so I my concern with these drugs is
- 30:17that they do have serious side effects,
- 30:19sometimes fatal side effects.
- 30:20And I'm very concerned that we're
- 30:23headed toward another Fen ven
- 30:25where we're so and and I again,
- 30:28I don't think people are doing
- 30:29this to harm higher weight people,
- 30:30but I think people have spent their careers,
- 30:32we've got this paradigm entrenchment
- 30:34that like we have got to get higher
- 30:36weight people to lose weight.
- 30:37And we have absolutely failed at
- 30:39every intervention we've tried.
- 30:40And Oh my God,
- 30:41here's the thing that quote UN quote works.
- 30:42So put everybody on it And the drug
- 30:45companies are doing a really good job
- 30:47of working hard to expand their markets
- 30:49progressively older and younger populations,
- 30:51progressively lower BMI populations,
- 30:54often using this idea of quote UN
- 30:56quote weight related conditions.
- 30:58So I'm,
- 30:58I'm very concerned that we're not
- 31:00having a full discussion about this and
- 31:02we're really jumping the gun and that
- 31:03a lot of people are going to get harmed.
- 31:07Thank you so much, So much to unpack here.
- 31:09It's a lot. Yeah. So I want to
- 31:13sort of dig into the culture of
- 31:15weight loss and the war on obesity.
- 31:20Can we talk about when that started
- 31:22and I asked that question because
- 31:24you showed us some excellent studies
- 31:26that showed a lack of effect of
- 31:29dieting and weight loss programs on
- 31:31the health of higher weight people.
- 31:33And some of those studies are old.
- 31:36I mean from my perspective,
- 31:37you know, 2003, 2013.
- 31:41So the only reason why studies
- 31:44like that haven't taken hold
- 31:45and aren't more widely discussed
- 31:47must be a cultural reason.
- 31:49So can you tell us what is the war
- 31:52on obesity? When did it start?
- 31:53Why did it start?
- 31:54Yeah. So to go way back the when,
- 31:59the World Health Organization classified,
- 32:01quote, obesity as a disease,
- 32:03that meeting was paid for by the
- 32:06International Obesity Task Force.
- 32:07The International Obesity Task Force
- 32:09was funded by two drug companies who
- 32:11had weight loss drugs coming out.
- 32:12They asked The Who to have the meeting
- 32:14and who said we don't have money
- 32:15for that And they said no problem,
- 32:16they paid for the meeting,
- 32:17they drafted the statements and then
- 32:20they bypassed the Who's editorial
- 32:21review and sent it out to health
- 32:23ministers of over 100 countries.
- 32:25And then the committee for the NIH
- 32:28said that they felt pressured to
- 32:30conform to the Who's definitions.
- 32:32And also the committee for the
- 32:34NIH had nine people and seven of
- 32:36them had like huge financial ties
- 32:38to the weight loss industry.
- 32:40And that committee was chaired by someone
- 32:41who was a former executive director and
- 32:44current board member of Weight Watchers.
- 32:46So the weight loss industry has been in
- 32:48it since the beginning and continues to
- 32:50be in it in a lot of different ways.
- 32:52And then Richard Carmona,
- 32:54who was the surgeon general at the time,
- 32:58said that obesity was a bigger
- 33:01threat than terrorism.
- 33:03And so that was sort of what started
- 33:05the the whole war on obesity.
- 33:07We need this global war on obesity
- 33:09and and the ridiculous notion that
- 33:11you can want to eradicate fatness
- 33:14without stigmatizing fat people,
- 33:16right, which is simply not possible.
- 33:19And so this whole war on obesity
- 33:22at that point,
- 33:23that's when we saw the money get
- 33:25earmarked only for research around,
- 33:27quote UN quote,
- 33:28obesity treatment and prevention where
- 33:30it's incredibly difficult to fund
- 33:32anything that doesn't pathologize
- 33:34higher weight bodies and doesn't focus
- 33:35on manipulating the size of those bodies.
- 33:37That is when we started to see this
- 33:40huge global conglomerate of weight loss
- 33:43companies and the sort of astroturf
- 33:46organizations they funded, right?
- 33:48The Quote Obesity Action Coalition.
- 33:49When they were pushing the AMA to make,
- 33:51quote, obesity a disease.
- 33:53They had 10 platinum sponsors,
- 33:56all of whom were weight loss companies.
- 33:59Now they're down to 1 platinum sponsor.
- 34:01It's Novo Nordisk.
- 34:02They gave them about $600,000 last year.
- 34:05And the OAC lobbies heavily for
- 34:08insurance coverage of NOVOS drugs.
- 34:12Right?
- 34:12So you've got this incredible mixing often,
- 34:16not clearly,
- 34:18right.
- 34:19A lot of what Novo is doing with
- 34:20the GLP ones is taken right out
- 34:22of the playbook that Purdue Pharma
- 34:24used for its Oxycontin promotion.
- 34:26And it's tough.
- 34:27You can't talk about this for more than
- 34:28like 5 minutes without starting to
- 34:30sound like a tinfoil hat conspiracy theorist,
- 34:32because it is in many ways a conspiracy,
- 34:36right?
- 34:36And again,
- 34:36I think a lot of the people are who
- 34:39are part of this are well meaning.
- 34:40I think there are some people who are
- 34:43doing this for money and don't care much,
- 34:45right?
- 34:46We're talking about a company
- 34:47that price gouged insulin.
- 34:48So I think everything that
- 34:49Nova and artist does has
- 34:50to be viewed through that lens.
- 34:52And so now we've got people saying,
- 34:54oh the war on obesity isn't right, right.
- 34:56We don't want to stigmatize fat people,
- 34:58We just want to eradicate
- 34:59them from the earth,
- 34:59but like in a non stigmatizing way.
- 35:02So I think that that's sort of changing.
- 35:05They're also now.
- 35:06So many people are now falling
- 35:08all over themselves to say,
- 35:09oh, behavior based weight loss
- 35:12interventions don't work.
- 35:13People in my community have been screaming
- 35:15this from the rooftops since the 40s, right?
- 35:18And now the weight loss companies are like
- 35:21the last seven people to learn this fact,
- 35:23but only in the service of
- 35:24now we have more expensive,
- 35:26more dangerous interventions to
- 35:27foist on this population rather
- 35:29than maybe now is the time to
- 35:31actually start having weight neutral
- 35:33comparator groups in our research,
- 35:35right.
- 35:36One of the things that happens in the
- 35:38research is that like for Novo's drugs,
- 35:39they compared their drugs to a
- 35:41behavior based weight loss intervention
- 35:42that they said in the introduction
- 35:44of their study didn't work.
- 35:45Comparing your drug to a known
- 35:47poor intervention is like nice
- 35:49work if you can get it.
- 35:50But if they had had a weight
- 35:51neutral comparator group,
- 35:52then we could really see could these
- 35:54benefits be achieved without all the risks
- 35:56of these drugs and the enormous expense,
- 36:00right.
- 36:00Same thing with them,
- 36:01weight loss surgeries,
- 36:02often their comparator groups are
- 36:03people who wanted weight loss surgeries
- 36:05and were denied the surgeries,
- 36:06not like a galloping shock that this
- 36:08group of people would have worse outcomes
- 36:10than the surgical outcome group,
- 36:11right.
- 36:12But we don't.
- 36:13We're not digging into the research.
- 36:15And so I think to come back to your point,
- 36:18sorry to get off a bit but the this
- 36:21war on obesity has been something that
- 36:24people could sort of get behind easily,
- 36:29right?
- 36:29Oh these are fat people.
- 36:30And again that goes back and I,
- 36:31I absolutely do not intend to white
- 36:33explain racism, racism to anyone.
- 36:34But I'm the person with the mic.
- 36:36So I just want to make it clear
- 36:38like this goes back to to the fact
- 36:40that fatness is tied with blackness
- 36:41and with people of color in this
- 36:44way that it's easy to to just
- 36:46blend those two things together
- 36:47in ways that they intersect and
- 36:49that allows that to to flourish.
- 36:52Right. And I as I was telling you before,
- 36:55I'm kind of new to the
- 36:57study of weight stigma.
- 36:59But what you described in terms
- 37:01of the relationship between racism
- 37:03and weight stigma is something
- 37:06that I think black women especially
- 37:08have personal experience with,
- 37:09with, even if they can't name it.
- 37:12So I'm really thankful that
- 37:13you mentioned those two books
- 37:15earlier in the presentation,
- 37:17and I've only read one of them,
- 37:19so I'm going to read the other.
- 37:20Awesome. Yeah, yeah. Sabrina,
- 37:22Strings Fearing the Black Body
- 37:24and Deshawn Harris and Belly of
- 37:26the Beast are the two. Thank you.
- 37:29OK, so you, you mentioned how some
- 37:33studies attribute health issues,
- 37:36various comorbidities to higher weight,
- 37:40but they're confounders
- 37:41that we didn't look at.
- 37:42And one of those confounders is
- 37:45discrimination against higher weight.
- 37:46Folks, can
- 37:47you talk about the discrimination
- 37:50higher weight folks that happen
- 37:52specifically in healthcare context?
- 37:54Yeah, so there's within healthcare context,
- 37:58we first have practitioner bias,
- 37:59both implicit and explicit, right?
- 38:02So implicit is subconscious bias.
- 38:03And we live in a world with a
- 38:05tremendous amount of weight stigma.
- 38:06So again, not a galloping shock
- 38:07if we've internalized that.
- 38:09And so it can be very easy to see
- 38:11somebody who has higher weight
- 38:13and start making assumptions
- 38:14about them subconsciously, right.
- 38:16So we've got that and then
- 38:17we've got explicit bias.
- 38:18And these are people who have very specific,
- 38:20they're aware that they have
- 38:22stereotypes and negative beliefs
- 38:23about higher weight people.
- 38:24They're aware that they're acting on them,
- 38:27right. And I think part of
- 38:28what's causing this, ironically,
- 38:29is this whole war on obesity because
- 38:32doctors were trained for years and
- 38:33years and are still in some cases being
- 38:35trained that if people try hard enough
- 38:37they can lose weight and keep it off
- 38:38with behavior based interventions.
- 38:40There is literally nothing to support that.
- 38:42There is no reason in in the
- 38:44research to believe that is true,
- 38:45but that's what they've been told.
- 38:47And so they assume I give this advice to
- 38:49my patients and they don't lose weight
- 38:51or they lose weight and gain it back,
- 38:53they're non compliant.
- 38:53And so they think, OK,
- 38:55these patients don't want to help themselves.
- 38:57Why would I want to help them?
- 38:58And so it spins this kind of,
- 39:00you know, weight stigma in that way.
- 39:02So there's that there's bias.
- 39:04But then there's also,
- 39:05like we talked about research,
- 39:07research that doesn't include
- 39:08higher weight people, right.
- 39:10Research that only looks at how to
- 39:12make higher weight people thinner,
- 39:14not how to make higher weight
- 39:16people healthier.
- 39:17Research that specifically excludes
- 39:19any kind of intervention that
- 39:21doesn't involve weight loss, right.
- 39:23So you'll see guidelines created and
- 39:25one of the exclusion criteria was that
- 39:26the study looked at health and not wait.
- 39:28So when we exclude that from the research,
- 39:31when we say we're not even going to
- 39:32look at that, that's a huge problem,
- 39:35right?
- 39:35So you've got research bias,
- 39:36then you've got structural bias.
- 39:38And structural bias is when the
- 39:39things that higher weight people
- 39:41need either don't exist for them
- 39:42or don't exist in a specific space.
- 39:44And so we go back to, like,
- 39:45is there a chair I cannot fit.
- 39:47I cannot physically sit in any
- 39:49chair in this room.
- 39:50So if I were a student here and this was
- 39:52a room that I had to be in for a lecture,
- 39:55I would have to try to get my own chair,
- 39:57which isn't always something that
- 39:59happens because it's If people's
- 40:01weight is not considered a disability,
- 40:03then like,
- 40:04the disability services office
- 40:04doesn't have to help.
- 40:05I see this.
- 40:06I work with people a lot in spaces like
- 40:08this who aren't being accommodated.
- 40:10I went to the law student who took
- 40:12every test of law school sitting on
- 40:14the stairs because the testing room
- 40:15didn't have a chair that would fit her
- 40:16and they wouldn't make an accommodation,
- 40:17right.
- 40:18So it's the chairs,
- 40:20it's the blood pressure cuffs,
- 40:21it's the gowns, it's the Mr.
- 40:23is,
- 40:23it's the ultrasound,
- 40:24it's the research upon which the
- 40:26best practices and the tools in the
- 40:29pharmacotherapies were created.
- 40:30This research typically excluded
- 40:32higher weight people and then when
- 40:35their outcomes aren't as good,
- 40:36we say, Oh well,
- 40:37it's because they're higher weight.
- 40:38Obviously they have to be made into
- 40:40thin people rather than saying
- 40:42they're being treated in a healthcare
- 40:44system that wasn't made for them.
- 40:45There's an interesting study Sun
- 40:47ET al In 2012 looked at the 2009
- 40:50H 1N1 outbreak and higher weight
- 40:52people had much
- 40:53worse outcomes in terms of
- 40:55severe outcomes and death.
- 40:56And so at the time all of the
- 40:58studies coming out, we're like, well,
- 40:59what's wrong with fat bodies, right?
- 41:00Is it low grade inflammation
- 41:01due to quote, obesity?
- 41:02Is it that it's acting in the adipose
- 41:04tissue and what Sun and all found was
- 41:07simply that thinner people got earlier
- 41:09antiviral treatment than heavier people did,
- 41:11and that when that difference
- 41:12was controlled for,
- 41:13the difference in outcome disappeared.
- 41:16And so I wonder how often that's happening,
- 41:19right, that what we're seeing is inequality
- 41:21of treatment that gets blamed on fat bodies.
- 41:24So there's that kind of bias.
- 41:26There's a bias where if research
- 41:28shows that higher weight people
- 41:29have higher rates of complications
- 41:31than they're denied surgery, right.
- 41:33And we see this with BMI based denials
- 41:34which I would describe as healthcare
- 41:36held hostage for a weight loss ransom
- 41:37that most people will not be able to pay.
- 41:41And this is,
- 41:42I'm as a as she had said in my bio,
- 41:45I'm a certified patient advocate and
- 41:47this is typically the work that I do
- 41:49as an advocate is helping people who
- 41:50have been denied care that they need,
- 41:52often denied a surgery that they
- 41:54need or want,
- 41:55and then referred to weight loss surgery.
- 41:58Right.
- 41:58So your knee surgery is too dangerous,
- 41:59but we'll be very happy to take
- 42:01your perfectly healthy digestive
- 42:02system and create a disease state
- 42:04permanently that we're cool with, right?
- 42:06So there's a lot of that as well.
- 42:07So there's so many different layers
- 42:09of weight stigma,
- 42:10and structural stigma is one of
- 42:12those things that all stigma needs
- 42:14systemic changes.
- 42:15But weight stigma that is structural
- 42:18requires systemic change.
- 42:20You can have a fully fat affirming
- 42:22practitioner.
- 42:22You can have a fully fat affirming patient,
- 42:24but if the MRI isn't big enough,
- 42:26that patient will not get care.
- 42:29And I was just giving a talk to
- 42:30APA program where one of the the
- 42:32folks said when they were working
- 42:33in the emergency room,
- 42:34they had a patient pass away
- 42:36because they couldn't get an MRI.
- 42:38And that in a thinner patient they
- 42:40suspected there would have been
- 42:41no problem in getting the MRI and
- 42:42that patient would have lived.
- 42:43So these weight stigma can be fatal
- 42:47and it requires systemic change to solve.
- 42:51Thank you. And my next question.
- 42:53My next question falls directly from
- 42:55what you were just speaking about.
- 42:57And you've already mentioned
- 42:58some of these best practices,
- 42:59but I'll give you the chance to elaborate.
- 43:01In addition to the larger MRI machines,
- 43:04the larger blood pressure
- 43:06coughs and the thigh coughs,
- 43:07what can we do to better accommodate people,
- 43:12higher weight people?
- 43:15So I think there's a number of things.
- 43:18First, getting educated on the options
- 43:20for weight neutral care, right?
- 43:22And part of that is just if you're
- 43:24tempted to prescribe weight loss to
- 43:25say what would I prescribe to a thin
- 43:28person in the same situation, right.
- 43:29And making sure that you at least
- 43:31give that as an option to the patient.
- 43:33Real informed consent conversations
- 43:36that include things about data like
- 43:39for weight loss surgery, again,
- 43:40the comparator groups are really problematic.
- 43:42There's very little data more than 10
- 43:45years out and the data that exists
- 43:47often suggest that if a patient
- 43:48is below their baseline weight by
- 43:50any amount and they are not dead,
- 43:51they are a success.
- 43:53They typically only look at adverse
- 43:55events for the 1st 30 days,
- 43:57even though they're creating a situation
- 43:58where we know that people can experience
- 44:00long term malnutrition and long term
- 44:02serious significant side effects.
- 44:03So if you're only tracking adverse events
- 44:05for 30 days and you tracks, you know,
- 44:08improvements for a year and then you say see,
- 44:10this is a great idea,
- 44:11that's a huge problem and
- 44:13patients deserve to know.
- 44:15We don't really have much data after that.
- 44:18We're not sure what will happen,
- 44:20but we know, for example,
- 44:21that if you get this ruined,
- 44:23why you won't be able to meet
- 44:24your nutritional needs with food.
- 44:25I was recently on a panel with a woman
- 44:27who had that surgery and then very
- 44:31unexpectedly experienced homelessness.
- 44:32And so she knew she could not get
- 44:34the nutrition she needed without
- 44:35her supplements and she could not
- 44:36afford her supplements and there was
- 44:38literally nothing for her to do, right?
- 44:41So making sure that patients
- 44:42understand all of these things,
- 44:44there's I think sometimes what happens is,
- 44:46and again I think it comes often
- 44:48from a really well meaning place,
- 44:49but there's a paternalism that happens
- 44:52where the practitioner believes that
- 44:53this is the best thing for the patient.
- 44:56The practitioner perhaps has implicit
- 44:57bias that says if a patient is fat,
- 44:59then they're not smart enough to make
- 45:01decisions for themselves or obviously
- 45:02they're making poor decisions for themselves.
- 45:04So I've got to convince this
- 45:06patient to do what's best for them.
- 45:07And so maybe one of the ways I do that
- 45:09is I kind of hold back on that informed
- 45:11consent conversation and I say all
- 45:13medications have side effects which
- 45:14is both true and completely unhelpful
- 45:17in an informed consent context,
- 45:19right.
- 45:19So it's we've got to be having
- 45:21these conversations,
- 45:21we've got to be offering weight neutral
- 45:24options and we've got to be clear,
- 45:25look there are people of all sizes
- 45:27who have your exact same presentation
- 45:29and here's what we offer to people
- 45:32who are quote UN quote normal weight
- 45:34to whom we don't suggest weight loss.
- 45:36This is what we offer and offering
- 45:37those things to patients as well,
- 45:41excellent. So I want to take this time to
- 45:44open the floor to questions and
- 45:45for the people in the room,
- 45:47if you could just raise your hand,
- 45:48I'll bring you a microphone and we'll get
- 45:50some of the questions on Zoom as well.
- 45:55OK. We've got a couple questions. I'm coming.
- 45:58I'm so excited. This is my, I do the talk,
- 46:00so I can do the Q&A. So this is awesome.
- 46:06Hi, thank you for coming to talk to us.
- 46:09I I'm curious for for patients who
- 46:11say that they do want to lose weight,
- 46:13is it like, is it ever ethical for
- 46:16healthcare providers to help them do that?
- 46:18That's a great question.
- 46:19I think the first thing to do if a patient
- 46:22wants weight loss is to ask them why.
- 46:24And they will probably be surprised
- 46:26because this has probably
- 46:27never happened to them, right.
- 46:28They say you won't weight loss.
- 46:29I I won't weight loss the practitioners,
- 46:31because of course you do and then you
- 46:32just go on and usually the answer to why
- 46:34will fall into one of three buckets.
- 46:36They're trying to cure or
- 46:37prevent health issues.
- 46:38They're trying to increase mobility
- 46:40or ability or they're trying to
- 46:42escape weight stigma and it may
- 46:43be one or all of those buckets.
- 46:45And so for the first two buckets,
- 46:47we can offer weight neutral options, right?
- 46:50For both of those things,
- 46:51there are people of all sizes who
- 46:53have the same mobility and ability,
- 46:55who have the same cinematology
- 46:56and cardio metabolic profile.
- 46:57So we have weight neutral options
- 46:59and we can offer those.
- 47:01We can also offer weight loss,
- 47:03but we have to be honest about things
- 47:05like failure rates and the possible harm.
- 47:08And then the third bucket, weight stigma.
- 47:10That's the tough one,
- 47:11because weight stigma is real and
- 47:13it impacts people in very real ways,
- 47:15and their life would be better if they
- 47:17were thinner because of weight stigma.
- 47:19The problem is we don't have real
- 47:21good ways to make people thin.
- 47:23And so,
- 47:23again,
- 47:24I think informed consent is really important.
- 47:26I think to the extent that it's
- 47:27within the scope of whatever you're
- 47:28practicing to let people know there's
- 47:30a whole community out there who are
- 47:31working and surviving and thriving
- 47:33outside of weight loss, right?
- 47:35There's the weight neutral community,
- 47:36there's the fat activism community
- 47:38and letting people know about
- 47:40those resources as well.
- 47:42And for me, so I'm both fat and gay.
- 47:44I came out in Texas in the mid 90s,
- 47:46which was a super interesting time to be out.
- 47:47And I did a lot of political work around
- 47:49queer and trans rights and at that time,
- 47:51in my personal experience,
- 47:52and this is still happening
- 47:53to way too many people,
- 47:55but that's when they told me
- 47:56like OK being queer as a choice,
- 47:57it's a bad choice,
- 47:58it's bad for you,
- 47:59it's bad for society and homophobia
- 48:00is terrible.
- 48:01So you should really try to be straight.
- 48:03And I never bought into that
- 48:04as a queer person,
- 48:05but I did buy into it as a fat
- 48:06person for a really long time.
- 48:08And So what I realized was that
- 48:09I had spent years fighting my
- 48:11body on behalf of weight stigma,
- 48:13and that what I wanted to do instead was
- 48:15fight weight stigma on behalf of my body.
- 48:17And that choice made all the difference.
- 48:19And so letting people know
- 48:21that that is an option,
- 48:22especially if that's why if
- 48:23they're saying like I want to
- 48:24lose weight because I want to,
- 48:25you know,
- 48:26shop at the normal clothing stores or I,
- 48:28you know,
- 48:29want to escape weight stigma in whatever way
- 48:30they're experiencing it,
- 48:31I think that's really important.
- 48:33In terms of ethics, it really that's
- 48:36I think a really personal question.
- 48:38And some people won't have the option
- 48:40to say like I don't offer weight loss.
- 48:42Right. But I think that at the very least,
- 48:44it has to be a serious informed consent
- 48:46conversation so that people know,
- 48:47especially if they're undergoing,
- 48:48for example, behavior based interventions.
- 48:51Look, 95% of the time people lose weight
- 48:53short term and gain it back long term.
- 48:54Up to 66% of people gain back
- 48:56more weight than they lost.
- 48:58If that happens to you,
- 48:59that is not your fault.
- 49:00That is what every piece of research
- 49:02we have says will happen long term.
- 49:04And so you're, you know,
- 49:05you're welcome to do that and I
- 49:08will be here if it doesn't work.
- 49:09And I want you to know it's not your fault.
- 49:11I think it's important to remember patient
- 49:14centered care is still fully rooted in
- 49:16ethical evidence based medicine, right.
- 49:18So if a patient said, oh,
- 49:19I saw on a TikTok that I can fly
- 49:20if I jump off my roof and I think
- 49:22that would really cure my knee pain,
- 49:23right 'cause flying will take the
- 49:25pressure like right off that joint.
- 49:27It's still not patient centered
- 49:28care to like endorse their plan to
- 49:30jump off their garage and flap their
- 49:31arms really hard right even though
- 49:33they believe it will help them.
- 49:35And so I think we still have to always
- 49:36be coming from do I believe that
- 49:38this is an ethical evidence based
- 49:40intervention and what informed consent
- 49:41do I need to offer to the patient.
- 49:45I actually have a question
- 49:47sure which I never ask.
- 49:50I liked your comparison
- 49:51for best practices
- 49:53worth and patients and as you referred to as
- 49:55fat patients. But
- 49:56my question is actually what could
- 49:59what would you say to fat haters
- 50:04the people that just for
- 50:06one reason or another
- 50:09don't see the comparison
- 50:10don't don't understand do
- 50:15you I'm sorry, can you elaborate
- 50:16a little bit people who well, I,
- 50:18I the one that came to my mind was
- 50:20the show that's on TV my 600 LB Oh
- 50:22yeah. And and or
- 50:24just people in general
- 50:25that will make a comment,
- 50:27those rude, horrible comments
- 50:30that they would probably
- 50:31not say to a thin person,
- 50:33but they will say or under their
- 50:35breath say to someone who is fat.
- 50:37Yeah, I mean, so no matter, again,
- 50:40no matter what people think about
- 50:42being fat and health, it does not
- 50:45justify poor treatment of fat people, right.
- 50:48And so to those folks, I say like,
- 50:50I hope you get some help to work
- 50:51out your issues and I hope that
- 50:53you learn to behave better.
- 50:59Hi, I don't have
- 51:01like a specific question,
- 51:01but I was wondering if you could
- 51:03talk a little bit more about larger
- 51:04bodies and reproductive health.
- 51:05I just think like
- 51:06in classes, I've learned that higher
- 51:09way and like higher risk of like
- 51:12gestational diabetes and also just
- 51:14in general the culture about like
- 51:17getting your body back like postpartum
- 51:19and all that. Yeah.
- 51:21So for this in general I recommend Nicola
- 51:24Salmon's work and I see Ola Salmon.
- 51:27She does incredible work around
- 51:29fat fertility and fat pregnancy.
- 51:30I've done some written some some stuff
- 51:32with her and done some workshops with her.
- 51:34So I think again when we
- 51:36go back to the research,
- 51:37often it doesn't suggest the risk
- 51:40is as high as it's believed to be.
- 51:43Also, again,
- 51:43there's not good research that
- 51:46shows like would behavior based
- 51:48interventions improve these outcomes?
- 51:50And so I just saw a study and I
- 51:52haven't broken it down yet,
- 51:53but it's like maybe you know quote UN
- 51:55quote obese pregnant people shouldn't gain
- 51:57weight at all or should maybe lose weight.
- 52:00And there's other research that says
- 52:01that's probably not the best idea, right.
- 52:03So it's always about breaking
- 52:05down the research I think and then
- 52:08managing the situation, right.
- 52:10People who have high risk for
- 52:11pregnancies for various reasons get
- 52:13pregnant and that is their right.
- 52:15And so, like,
- 52:15how do we manage and help those
- 52:17folks rather than saying, like,
- 52:18you shouldn't got a you shouldn't
- 52:20have gotten pregnant, you know,
- 52:21you shouldn't exist as a pregnant person.
- 52:24You don't deserve help any problem.
- 52:25And this is what I hear people say,
- 52:27like, yeah,
- 52:27I was getting an epidural and my
- 52:29doctor said that if I had any problems,
- 52:31it would be my fault and that I
- 52:32should never have gotten fat.
- 52:33Like, while they were giving the
- 52:35epidural out of scope.
- 52:37Inappropriate, right?
- 52:38So there's the way that weight
- 52:40stigma also impacts.
- 52:41Do people get all of their care?
- 52:42Do they skip prenatal visits,
- 52:43'cause they just cannot deal with
- 52:45another weight lecture, right?
- 52:46So there's all of that.
- 52:47And then the culture around getting like,
- 52:48pregnancy body back is like that bit
- 52:52of diet culture is so, like odd to me.
- 52:55Like you made a whole person, right?
- 52:57And all we're like is do you look
- 52:59like you looked when you were 18?
- 53:00Who cares?
- 53:00Like that diet culture thing is
- 53:02a whole extra separate trip.
- 53:13Uh, huh.
- 53:22Now it's on.
- 53:24And so for me as a
- 53:24second year medical student,
- 53:26I'm thinking a lot about the sort of
- 53:28long term consequences of patients
- 53:30who are under insured or uninsured.
- 53:32And I think if you look at the landscape
- 53:34of the American Insurance you know,
- 53:36scheme, one in 10 people are not insured.
- 53:39And if you look at you know the sort
- 53:41of breakdown of who those people are,
- 53:43they tend to be people who are you know,
- 53:44from lower socio economic groups,
- 53:46you know face you know different barriers,
- 53:48social determinants of health etcetera.
- 53:50And I guess my question is when
- 53:53you are charting and you write
- 53:56the word obesity in a chart,
- 53:58insurance companies from what I
- 54:00understand have sort of limited,
- 54:01my limited knowledge is that they do often
- 54:05elevate rates for people who are obese
- 54:07or those those sort of rates are are in,
- 54:10you know,
- 54:11they're informed by the charts.
- 54:13But I want my patients to be
- 54:15insured because people who are
- 54:17insured have better health outcomes.
- 54:19So you see the issue here, right?
- 54:20Like, what is the purpose of documenting
- 54:22that in a chart that then might,
- 54:25you know,
- 54:25affect someone's insurance status to the
- 54:27point where they are no longer insured
- 54:30and then they're jeopardized further by
- 54:32a system that they can't support them.
- 54:34So I'm curious, I guess,
- 54:34as a comment, how does charting,
- 54:37you know,
- 54:38maybe affect people's insurance status?
- 54:40And how does insurance status
- 54:42affect people's health as as
- 54:43people who present with obesity?
- 54:44So I don't know.
- 54:45Yeah,
- 54:46that's a great question.
- 54:47This has gotten a lot better
- 54:49since the Affordable Care Act.
- 54:50Prior to that when insurance
- 54:52companies were allowed to deny
- 54:53people for pre-existing conditions.
- 54:55You may or may not remember
- 54:56when that was the case,
- 54:57high BMI was considered a
- 54:59pre-existing condition.
- 54:59I personally could not get
- 55:01healthcare for 14 years because my
- 55:04body was considered a pre-existing
- 55:05condition that insurance companies
- 55:07were not required to cover.
- 55:09And so that's not the case anymore.
- 55:10They're not allowed to stratify
- 55:12based on body size.
- 55:13It's just smoking in age at this point.
- 55:16If they're under an Obamacare
- 55:18and Affordable Care Act plan,
- 55:19if they're doing the like independent
- 55:21private plans and they can,
- 55:22it's they can do whatever they want.
- 55:23Unfortunately for me,
- 55:25the the charting around,
- 55:27quote UN quote, obesity,
- 55:28first of all,
- 55:28it can trigger a lot of like
- 55:30communications with the patient
- 55:31that that patient may not want.
- 55:33Especially let's say the patient
- 55:34is higher weight and experiencing
- 55:35an eating disorder, right.
- 55:36And they're getting all of this
- 55:38weight loss stuff that can be
- 55:40incredibly triggering and problematic
- 55:41also like life insurance and
- 55:43long long term care insurance.
- 55:44Those things are deeply impacted by weight.
- 55:47I cannot get either because of
- 55:51my BMIA lot of people can't.
- 55:52So that's a huge problem.
- 55:54So, yeah,
- 55:54I think the the way that we chart
- 55:56size and the fact that it's been
- 55:59put into requirement like the MIPS,
- 56:00if you're working with with Medicare,
- 56:03one thing to know is that with
- 56:04MIPS if the patient refuses weigh
- 56:06in or declines weigh in,
- 56:07it removes them from both the numerator
- 56:09and the denominator of the miscalculation.
- 56:11So it does not count against
- 56:13the compensation.
- 56:14If that is removed,
- 56:15of course you have to have an
- 56:16EHR that will do that,
- 56:17which is a whole other thing.
- 56:19So I think in terms of like
- 56:20their health insurance,
- 56:21it doesn't necessarily cause an
- 56:23immediate problem in terms of
- 56:25like their cost of insurance,
- 56:27it doesn't make it go up,
- 56:28but it can create barriers,
- 56:30it can create step programs with
- 56:32certain insurances where like they're
- 56:33expected to try different things.
- 56:35And this is one of the huge concerns
- 56:37with the big push right now.
- 56:39Novo Nordisk and Eli Lilly are in
- 56:41a huge full court press to mandate
- 56:43Medicare coverage of their weight loss drugs,
- 56:46which is odd because Medicare is
- 56:48almost entirely people 65 and up.
- 56:50And that's a group of people where
- 56:51there's a large body of research
- 56:53that shows that they that weight
- 56:55loss creates increased mortality.
- 56:56So I have some concerns about that.
- 56:58They're also pushing.
- 56:59I just want to point out that access
- 57:01to these drugs for black and brown
- 57:04communities is a social justice issue.
- 57:05But black and brown communities were
- 57:07vastly underrepresented in their trials.
- 57:09Meaning this is basically just
- 57:11replicating a history of experimental
- 57:13medicine on people of color.
- 57:14And I think that's something that
- 57:15we need to keep pointing out.
- 57:17So I think that that in terms of charting,
- 57:19that's the bigger issue to me.
- 57:21I also just want to point out like there's
- 57:23there's the thing where they say, oh,
- 57:24people of lower socio economic status
- 57:26have a higher chance of being fat.
- 57:28But I also want to point out that
- 57:30people who are fat have a lower,
- 57:31have a higher chance of
- 57:33being lower economic status,
- 57:34right higher way people are hired less,
- 57:36paid less and promoted less than
- 57:38similarly qualified than people.
- 57:39One study found that higher weight women,
- 57:41the penalty was about $19,000
- 57:43over very thin women.
- 57:45So it's not like a small amount of money.
- 57:47So I think that we also always
- 57:48need to be looking at like the
- 57:49chicken and the egg problem there,
- 57:51which is way more than you asked for,
- 57:52but that's what I got.
- 57:55I thank you for a wonderful
- 57:56talk and advocating for patients.
- 57:59Could you please clarify a little bit
- 58:02the statement that you made about the
- 58:04increased risks of the GLP one medications?
- 58:07I think you had compared it to the Fen
- 58:10Fen from from Eris prior because you know
- 58:14there there's not as much long term data
- 58:17on the obesity dosings of the GLP ones.
- 58:21But there's plenty of long term data
- 58:23and big study data is using the same
- 58:25agents in diabetic trials and they,
- 58:28you know mostly for all agents have shown
- 58:31improvement in three or four point Mace.
- 58:33It's being used in heart
- 58:36failure kidney disease.
- 58:37So you know,
- 58:38those seem like they're quite beneficial
- 58:40for patients who have comorbidities.
- 58:42But what,
- 58:43what is the concern about the higher
- 58:46doses for obesity management?
- 58:49Yeah, so there there's a couple of concerns.
- 58:51The 1st is just that it's
- 58:53more than the maximum dose.
- 58:54So while we have data on the diabetes doses,
- 58:56that titration and dosing is very different
- 58:59for weight loss because the goal of
- 59:01that is to maximize side effects, right.
- 59:02So it has good health benefits and I
- 59:04agree that it's a solid type 2 diabetes
- 59:06drug and has other benefits as well,
- 59:08like the idea that we wouldn't
- 59:09give it at that dosage,
- 59:10but that we could keep cranking up
- 59:11the dosage to produce weight loss,
- 59:13to produce the side effect means that
- 59:16we're going to increase the rates
- 59:18of all those dependent side effects.
- 59:20So there's that piece of it
- 59:22that's concerning.
- 59:23There's also the concern that we don't know.
- 59:24Now one of the chief benefits of these
- 59:28drugs in terms of type 2 diabetes is
- 59:29that they only act when glucose is high.
- 59:31So there are fewer hypo incidents
- 59:33on these drugs.
- 59:33However,
- 59:34people who don't have type 2
- 59:36diabetes do have glucose spikes.
- 59:38And what we don't know and what some
- 59:39endocrinologists are asking is what
- 59:40happens when we give people a mega
- 59:42dose of a type 2 diabetes drug and
- 59:43they don't have type 2 diabetes.
- 59:45So when they have a normal blood sugar spike,
- 59:47does that then like hammer the beta cells,
- 59:50exhaust them sooner and create an
- 59:51earlier presentation or presentation
- 59:53that never would have happened of type
- 59:542 diabetes in that patient, right.
- 59:56We don't have an answer to that
- 59:58question because we don't have
- 59:59a long term data on of people on
- 01:00:01these high doses of the drug.
- 01:00:02So that's the concern in general.
- 01:00:04My Fen Fen concern is that
- 01:00:07it's not just the side effects,
- 01:00:08but the fact that we've got a medication
- 01:00:10that shows short term weight loss,
- 01:00:13right,
- 01:00:13that in two years weight loss levels
- 01:00:15off around like that 58 to 62 week mark.
- 01:00:17And then sort of studies with TIRZEPATITIS,
- 01:00:21studies with Novo Nordisk at 68 weeks,
- 01:00:23sort of a weight cycling.
- 01:00:25Thing happens with the mean weight
- 01:00:26loss and then at the end of two
- 01:00:28years weight is is going up and
- 01:00:30that's when the data stops.
- 01:00:32So that's a concern.
- 01:00:34The fact that their own 100 year
- 01:00:36patient adverse data shows that
- 01:00:37every 25 years people are looking
- 01:00:39at three serious adverse events and
- 01:00:42one adverse event serious enough
- 01:00:44to discontinue the medication.
- 01:00:46And again,
- 01:00:46because this is the same as weight
- 01:00:48loss drugs have always been,
- 01:00:49when people go off of it,
- 01:00:49they regain the weight.
- 01:00:51And Novo notice unbelievably
- 01:00:52profitable solution is will people
- 01:00:54just stay on this drug for life.
- 01:00:55And that's why we're seeing this redefinition
- 01:00:57of obesity isn't just a disease,
- 01:00:59it's a chronic lifelong relapsing remitting
- 01:01:01disease which covers all of their bases,
- 01:01:03right.
- 01:01:04If people weight cycle on the drug,
- 01:01:06well that's the relapsing remitting nature
- 01:01:07of the quote UN quote disease, right.
- 01:01:10It's chronic and lifelong like asthma.
- 01:01:11So you have to take it forever,
- 01:01:13except that it's not like asthma or
- 01:01:15type 2 diabetes because there's no
- 01:01:17real definition of obesity that is
- 01:01:21separate from other conditions, right.
- 01:01:23They. So there have been, if you look,
- 01:01:26there's no clear definition.
- 01:01:27We've had the BMI definition.
- 01:01:30But the the new definitions are like,
- 01:01:32oh, well, it's excess fatness that
- 01:01:34impacts health, which is not really the
- 01:01:36way you diagnose the disease, right.
- 01:01:37Because it's like saying, well,
- 01:01:39if you're 6 foot seven, you're just tall,
- 01:01:40but if you're 6 foot seven with hypertension,
- 01:01:42now you're medically over tall, right.
- 01:01:45And so the the thing with these,
- 01:01:47with these drugs that is concerning
- 01:01:49to me is that we're almost 70% of the
- 01:01:52population is eligible for them and
- 01:01:55they're pushing really hard to get
- 01:01:56insurance coverage for Medicare so
- 01:01:57that they can get private insurance.
- 01:01:59They're pushing really hard to get
- 01:02:00them formularies in other countries.
- 01:02:01And we don't have a lot of data.
- 01:02:03There are serious and including
- 01:02:05fatal side effects of these drugs,
- 01:02:07and we don't know what that will
- 01:02:08look like at this dose.
- 01:02:09And we are racing to get them to people.
- 01:02:12And that is what concerns me
- 01:02:13about another fan event.
- 01:02:17So we have time for one
- 01:02:19more question from the room.
- 01:02:24Anyone else have a question?
- 01:02:28Yes, Doctor Hall. Really
- 01:02:40loud. Karen's going to give
- 01:02:41it to you. I'm sorry. Yeah,
- 01:02:43they're bringing the mic.
- 01:02:43We are. We do have a bunch of
- 01:02:45people on Zoom. So hi Zoomers,
- 01:02:55can you hear me Perfect.
- 01:02:57Thank you for that,
- 01:02:58that very informative talk.
- 01:02:59I was wondering if you could
- 01:03:00speak a little bit more about,
- 01:03:02you know you mentioned the
- 01:03:04intersection between anti between
- 01:03:06weight related stigma and racism.
- 01:03:09But you also touched a little bit on
- 01:03:11how that may intersect with sexism,
- 01:03:13particularly with respect to,
- 01:03:15you know, I would say sort of the,
- 01:03:18you know, get your pre pregnancy
- 01:03:19body back and just this idea that
- 01:03:21you know somehow women are vessels
- 01:03:23and you know you have to gain weight
- 01:03:25to produce the the pregnancy.
- 01:03:27But then afterwards you know you better,
- 01:03:29you better get that body back in shape
- 01:03:31so that you can be desirable because
- 01:03:33otherwise like what's your value?
- 01:03:35Obviously I'm exaggerating,
- 01:03:36although sadly not that much.
- 01:03:39And then you know also you,
- 01:03:41you reference the correlation
- 01:03:42between weight and socioeconomic
- 01:03:44status and certainly you have more
- 01:03:46expertise in this area than I.
- 01:03:47But the what I've read on that
- 01:03:49actually that that's pretty gender
- 01:03:51specific and that for men the
- 01:03:54correlation between weight and
- 01:03:56earnings does not hold particularly.
- 01:03:58Whereas with women,
- 01:04:00there's a stark difference in terms of pay,
- 01:04:03in terms of what,
- 01:04:05you know,
- 01:04:05weight stigma and how like economically
- 01:04:08there's a huge advantage to being
- 01:04:10thin because the stigma is so great
- 01:04:12for professional women in particular.
- 01:04:15So I was wondering if you could
- 01:04:16just speak a little bit more
- 01:04:17about that and some of the work
- 01:04:18that's been done in that area.
- 01:04:19And and what are you,
- 01:04:21what do you think are some of
- 01:04:22the underpinnings of of of that?
- 01:04:23Because I think it's,
- 01:04:24it's really salient to
- 01:04:25this conversation as well.
- 01:04:27Yeah. So I'll do the last one first.
- 01:04:29A new report has just come out that has
- 01:04:31found that in fact the wage penalty
- 01:04:33for higher weight men is much worse
- 01:04:36than was recently believed. Right.
- 01:04:38So up till now there's been the general
- 01:04:40belief that the penalty isn't as bad
- 01:04:41for CIS men as it is for CIS women.
- 01:04:43And while that's true,
- 01:04:44it seems that it is much steeper for CIS men,
- 01:04:47especially if you start to
- 01:04:49striate by education.
- 01:04:50So the more education someone has,
- 01:04:52the the bigger the penalty is.
- 01:04:55So that data was for the for a
- 01:04:57long time was what was believed.
- 01:04:59And now it's seeming that that may not
- 01:05:01be true and that if we really striate
- 01:05:03there is a significant difference.
- 01:05:05And in general,
- 01:05:06I mean the weight loss in the beauty
- 01:05:09industries have made billions of dollars
- 01:05:11by creating the Sisyphean task, right?
- 01:05:13You have.
- 01:05:13We have a solution to sell you.
- 01:05:15So you have a problem, right?
- 01:05:17You should spend as much time and
- 01:05:19energy and money as you possibly can
- 01:05:21trying to attain a stereotype of
- 01:05:23beauty that is firmly rooted in thin
- 01:05:25white CIS het currently able bodied youth.
- 01:05:29And you will probably never get there.
- 01:05:30But that is not a good reason not to try,
- 01:05:33right?
- 01:05:33That has been the underpinning.
- 01:05:35And it's also why intersectionally,
- 01:05:37it creates so many problems for people
- 01:05:39with multiple marginalized identities,
- 01:05:41right?
- 01:05:41Because you've got all of these
- 01:05:43different aspects of the stereotype
- 01:05:45of beauty that will be unattainable
- 01:05:47for you and even people who attain it.
- 01:05:49It hurts people who attain that
- 01:05:51stereotype of beauty because then they
- 01:05:53live in terror of losing that right,
- 01:05:55the privilege that that creates,
- 01:05:56the opportunities that that creates for them.
- 01:05:59And so they tend to spend a ton of
- 01:06:01time and energy and money trying
- 01:06:02to maintain that privilege.
- 01:06:03So that's been the underpinning of
- 01:06:05diet culture for a really long time.
- 01:06:07And it's, you know,
- 01:06:08we can see it and pull it apart
- 01:06:10in each aspect.
- 01:06:10And the whole pregnancy body for
- 01:06:13people who can get pregnant is
- 01:06:14certainly a huge part of that, right.
- 01:06:16It's this market that they have
- 01:06:18of people who, you know,
- 01:06:19now you need to get your pregnancy
- 01:06:21body back and this, you know,
- 01:06:23this whole diet culture piece of it.
- 01:06:25But I think it's all sort of based
- 01:06:27on that Sisyphean idea of attaining
- 01:06:29that stereotype of beauty and that
- 01:06:31that's our responsibility and that
- 01:06:32we owe other people aesthetically
- 01:06:34pleasing by their own definition.
- 01:06:37And I think that that one of the
- 01:06:39things that I looked at in my own
- 01:06:42journey was what if perceiving
- 01:06:43beauty was a skill set?
- 01:06:45So if I don't see the beauty in someone,
- 01:06:46that's on me because we're not asked
- 01:06:48to develop that skill set, right?
- 01:06:49We're told this is beauty.
- 01:06:50Everything else isn't.
- 01:06:51This isn't beauty done easy.
- 01:06:53So what if the ability to perceive
- 01:06:54a beauty is
- 01:06:55a skill set that we don't develop?
- 01:06:56And so then it's my responsibility.
- 01:06:58And if somebody can't see the beauty in me,
- 01:06:59that's not on me, that's their
- 01:07:01responsibility to develop that skill set.
- 01:07:03And maybe they never do, but I don't
- 01:07:05take responsibility for that, right?
- 01:07:07I don't owe people aesthetically pleasing
- 01:07:08based on their definition and the same thing.
- 01:07:11I think often this gets intertwined
- 01:07:15with the idea of health, right?
- 01:07:17So whatever the current standard
- 01:07:18of beauty is is also what quote,
- 01:07:20UN quote, healthier fit looks like.
- 01:07:22And so I think it's really important
- 01:07:24that we're always saying health
- 01:07:25is not an obligation, right.
- 01:07:26Which I know because there's a the
- 01:07:28whole NFL where the goal is to risk
- 01:07:30your short and long term physical
- 01:07:31and mental health in the hope that
- 01:07:33someday your team will score enough
- 01:07:34points to win a shiny piece of jewelry.
- 01:07:36You're allowed to do that,
- 01:07:38but it does not prioritize the health.
- 01:07:40The sport of skeleton in the Olympics,
- 01:07:4180 miles an hour down an ice
- 01:07:43chute on a sled face first,
- 01:07:44does not prioritize the health, right.
- 01:07:47So there's that piece of the
- 01:07:48health is not an obligation,
- 01:07:50it's not a barometer of worthiness.
- 01:07:51It's not entirely within our control.
- 01:07:54And it's a really gooey,
- 01:07:55amorphous concept, right.
- 01:07:57And just like beauty,
- 01:07:58we tend to act like health is as simple,
- 01:08:00like you could throw a dart and hit it.
- 01:08:01That's healthy, right?
- 01:08:02It's a simple definition.
- 01:08:03I put people in and out of it.
- 01:08:04But when we look at individuals,
- 01:08:07it's so different.
- 01:08:08If you take for one example,
- 01:08:09somebody who has no chronic
- 01:08:11conditions versus someone who's just
- 01:08:12developed a chronic condition versus
- 01:08:14somebody who's been dealing with six
- 01:08:16chronic conditions over a decade,
- 01:08:17their concepts of what health and Wellness
- 01:08:19look like will be very different.
- 01:08:21But that doesn't make any of
- 01:08:22them wrong and just say, well,
- 01:08:23some people are healthy and
- 01:08:24some people are not,
- 01:08:25doesn't do a service to anybody.
- 01:08:28Rather than saying,
- 01:08:29OK,
- 01:08:29based on this person's personal
- 01:08:31goals and priorities and situation,
- 01:08:33what is it that they're looking
- 01:08:34for in terms of health?
- 01:08:35And I think that also can be
- 01:08:38ascribed then over to the idea of
- 01:08:40this beauty standard that is used
- 01:08:42and abused within the healthcare
- 01:08:43system and within the greater world.
- 01:08:48So we are unfortunately over time.
- 01:08:51But I just wanted to take the
- 01:08:52opportunity to thank you, Reagan,
- 01:08:54for coming to speak to us.
- 01:08:56It takes a lot of courage to try
- 01:08:58to push back against a cultural
- 01:09:00paradigm like the war on obesity,
- 01:09:02but that is the work of activism.
- 01:09:03So we appreciate you doing that work.
- 01:09:06And please give her a hand.
- 01:09:10Thank you very much.
- 01:09:13And again, thank you for
- 01:09:14all of the work you did.
- 01:09:15Thank you all for coming.
- 01:09:17It's been an honor.