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Phase I, Phase I-II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients With Advanced Solid Tumors Harboring a p53 Y220C Mutation (PYNNACLE)

What is the purpose of this trial?

This study will assess the safety, tolerability, and efficacy of multiple dose levels of PC14586 in participants with advanced solid tumors containing a TP53 Y220C mutation.

Contact Information

For more information about this study, including how to volunteer, contact Ingrid Palma

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  • Last Updated
    08/06/2024
  • Study HIC
    #2000032119