2024
Autism Spectrum Disorder and Grandmother’s Race, Ethnicity, and Nativity
Chow T, Meng Q, O’Sharkey K, Liew Z, Ritz B. Autism Spectrum Disorder and Grandmother’s Race, Ethnicity, and Nativity. JAACAP Open 2024 DOI: 10.1016/j.jaacop.2024.04.008.Peer-Reviewed Original ResearchIntellectual disabilityForeign-bornForeign-born whitesUS-born WhitesForeign-born blacksUS-born blacksForeign-born APIsUS-bornAsian-Pacific IslandersAutism spectrum disorderCalifornia DepartmentNativesGrandmothersPacific IslandersOdds ratioGrandchildrenEthnicityOffspring autism spectrum disorderRaceSelf-reported raceBirth certificatesMother-child pairsStudy investigated associationsWhitePublic health
2023
Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children
Vilhelmsson A, Rylander L, Jöud A, Lindh C, Mattsson K, Liew Z, Guo P, Ritz B, Källén K, Thacher J. Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children. The Science Of The Total Environment 2023, 899: 165622. PMID: 37474063, DOI: 10.1016/j.scitotenv.2023.165622.Peer-Reviewed Original ResearchConceptsOdds ratioPreterm infantsEarly pregnancyPerfluorononanoic acidPrenatal PFAS exposureMaternal serum concentrationsCerebral palsy casesConfidence intervalsCase-control studyRisk of CPEnvironmental risk factorsPositive associationContinuous variablesHigh PFASPalsy casesBirth RegistryPreterm controlsCerebral palsyLifestyle factorsPreterm casesUnexplained etiologyPrenatal exposureSerum concentrationsRisk factorsPerfluorooctane sulfonateHyperthyroidism in Danish Pregnant Women During a 20-Year Period
Torp N, Liew Z, Carlé A, Karmisholt J, Pedersen I, Andersen S, Andersen S. Hyperthyroidism in Danish Pregnant Women During a 20-Year Period. The Journal Of Clinical Endocrinology & Metabolism 2023, 109: e370-e378. PMID: 37437100, DOI: 10.1210/clinem/dgad410.Peer-Reviewed Original ResearchConceptsDanish pregnant womenOccurrence of hyperthyroidismAntithyroid drugsPregnant womenBiochemical hyperthyroidismMandatory iodine fortification programmeNationwide register-based cohortUse of ATDsRegister-based cohortIodine fortification programGeneral Danish populationNationwide cohortAutoimmune hyperthyroidismMaternal useOdds ratioTime-related differencesHyperthyroidismBirth cohortClinical concernBaseline levelsDanish populationFortification programsPregnancyCohortYoung individualsAssociation Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark
Liew Z, Meng Q, Yan Q, Schullehner J, Hansen B, Kristiansen S, Voutchkova D, Olsen J, Ersbøll A, Ketzel M, Raaschou-Nielsen O, Ritz B. Association Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark. JAMA Pediatrics 2023, 177: 617-624. PMID: 37010840, PMCID: PMC10071398, DOI: 10.1001/jamapediatrics.2023.0346.Peer-Reviewed Original ResearchConceptsMaternal exposureOdds ratioStratified analysisNationwide population-based case-control studyPopulation-based case-control studyDanish Medical Birth RegistryDanish Psychiatric Central RegisterAutism spectrum disorderMedical Birth RegistryNovel environmental risk factorTenth Revision codesAdverse birth outcomesControl participantsMaternal prenatal exposureMaternal residential addressBirth yearCase-control studyPsychiatric Central RegisterMood-stabilizing effectsAir pollution exposureEnvironmental risk factorsInternational Statistical ClassificationWnt/β-catenin signalingStudy teamRelated Health ProblemsResidential proximity to unconventional oil and gas development and birth defects in Ohio
Gaughan C, Sorrentino K, Liew Z, Johnson N, Clark C, Soriano M, Plano J, Plata D, Saiers J, Deziel N. Residential proximity to unconventional oil and gas development and birth defects in Ohio. Environmental Research 2023, 229: 115937. PMID: 37076028, PMCID: PMC10198955, DOI: 10.1016/j.envres.2023.115937.Peer-Reviewed Original ResearchConceptsNeural tube defectsCertain birth defectsBirth defectsOdds ratioRegistry-based cohort studyTube defectsConfidence intervalsResidential proximityState birth recordsBirth defect typeState surveillance systemsMaternal residential proximityLimb reduction defectsCohort studyUnexposed mothersStructural birth defectsLive birthsInfant sexBirth recordsSpina bifidaReduction defectsFemale offspringDevelopmental toxicantsExposure metrics