Irritability in Youths: A Critical Integrative Review
Leibenluft E, Allen L, Althoff R, Brotman M, Burke J, Carlson G, Dickstein D, Dougherty L, Evans S, Kircanski K, Klein D, Malone E, Mazefsky C, Nigg J, Perlman S, Pine D, Roy A, Salum G, Shakeshaft A, Silver J, Stoddard J, Thapar A, Tseng W, Vidal-Ribas P, Wakschlag L, Stringaris A. Irritability in Youths: A Critical Integrative Review. American Journal Of Psychiatry 2024, 181: 275-290. PMID: 38419494, DOI: 10.1176/appi.ajp.20230256.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderPathophysiology of irritabilityResponse to frustrationParent management trainingTreating psychological problemsDeficit hyperactivity disorderAutism spectrum disorderPrevalence of irritabilityAssociated with impairmentDiverse longitudinal sampleAssociated with increased risk of anxietyRisk of anxietyYouth irritabilityAnxiety disordersTreating irritabilityHyperactivity disorderBehavior problemsSpectrum disorderDevelopmental trajectoriesAssess irritabilityPsychological problemsLongitudinal sampleImpact of cultural contextTranslational findingsSuicide