Hepatotoxicity assessment of innovative nutritional supplements based on olive-oil formulations enriched with natural antioxidants
Prodromou S, Chatzopoulou F, Saiti A, Giannopoulos-Dimitriou A, Koudoura L, Pantazaki A, Chatzidimitriou D, Vasiliou V, Vizirianakis I. Hepatotoxicity assessment of innovative nutritional supplements based on olive-oil formulations enriched with natural antioxidants. Frontiers In Nutrition 2024, 11: 1388492. PMID: 38812942, PMCID: PMC11133736, DOI: 10.3389/fnut.2024.1388492.Peer-Reviewed Original ResearchNutritional supplementsLong-term effects of oxidative stressOxidative stressCell culturesReal-time PCRNatural antioxidantsEvaluate cell viabilityGene expression profilesPotential nutritional supplementEffects of oxidative stressHepG2 cell culturesMolecular pathophysiologyTherapeutic strategiesQuantitative real-time PCRInflammatory signalingAlleviate symptomsAlzheimer's diseaseLong-term effectsLong-term consequencesProliferation capacityMolecular pathwaysCell toxicityDelivery modeCellular toxicityOlive-oil