2024
Phylogeographic Analysis of Mycobacterium kansasii Isolates from Patients with M. kansasii Lung Disease in Industrialized City, Taiwan - Volume 30, Number 8—August 2024 - Emerging Infectious Diseases journal - CDC
Cudahy P, Liu P, Warren J, Sobkowiak B, Yang C, Ioerger T, Wu C, Lu P, Wang J, Chang H, Huang H, Cohen T, Lin H. Phylogeographic Analysis of Mycobacterium kansasii Isolates from Patients with M. kansasii Lung Disease in Industrialized City, Taiwan - Volume 30, Number 8—August 2024 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2024, 30: 1562-1570. PMID: 39043390, PMCID: PMC11286038, DOI: 10.3201/eid3008.240021.Peer-Reviewed Original ResearchConceptsM. kansasii lung diseaseM. kansasii pulmonary diseasePulmonary diseaseM. kansasii isolatesSputum mycobacterial cultureWhole-genome sequencingEvaluate risk factorsPhylogeographic analysisAge of participantsGenetic relatednessEnvironmental acquisitionLung diseaseMycobacterial cultureOdds ratioRisk factorsM. kansasiiPatientsDiseasePlantsEnvironmental transmissionIsolatesPark plantingsCDCRisk
2018
The impact of migration on tuberculosis in the United States
Menzies NA, Hill AN, Cohen T, Salomon JA. The impact of migration on tuberculosis in the United States. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 1392-1403. PMID: 30606311, PMCID: PMC6353558, DOI: 10.5588/ijtld.17.0185.Peer-Reviewed Original ResearchConceptsTB casesTB burdenHigher tuberculosis ratesNew TB casesLow-incidence settingsEntry yearActive TBTB epidemiologyTB riskIncidence estimatesTuberculosis ratesLifetime casesUnited StatesRiskPopulation residentGreater exposureBurdenNative-born populationPopulationCountry of originTBYearsTuberculosisCasesInfectionInvestigating spillover of multidrug-resistant tuberculosis from a prison: a spatial and molecular epidemiological analysis
Warren JL, Grandjean L, Moore DAJ, Lithgow A, Coronel J, Sheen P, Zelner JL, Andrews JR, Cohen T. Investigating spillover of multidrug-resistant tuberculosis from a prison: a spatial and molecular epidemiological analysis. BMC Medicine 2018, 16: 122. PMID: 30071850, PMCID: PMC6091024, DOI: 10.1186/s12916-018-1111-x.Peer-Reviewed Original Research
2017
Antimicrobial Resistance Risks of Cholera Prophylaxis for United Nations Peacekeepers
Kunkel A, Lewnard JA, Pitzer VE, Cohen T. Antimicrobial Resistance Risks of Cholera Prophylaxis for United Nations Peacekeepers. Antimicrobial Agents And Chemotherapy 2017, 61: 10.1128/aac.00026-17. PMID: 28533237, PMCID: PMC5527623, DOI: 10.1128/aac.00026-17.Peer-Reviewed Original ResearchConceptsDrug-resistant infectionsAntimicrobial chemoprophylaxisDrug-sensitive infectionsDrug resistance generationCholera importationChemoprophylaxisDrug resistanceImportation eventsInfectionAntibiotic resistanceAntimicrobial resistance risksRiskRelative benefitsResistance generationCholeraPotential resistance risksPotential benefitsResistance riskProphylaxisPrevalence
2016
Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling
Heidebrecht CL, Podewils LJ, Pym A, Mthiyane T, Cohen T. Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling. PLOS ONE 2016, 11: e0153143. PMID: 27050561, PMCID: PMC4822784, DOI: 10.1371/journal.pone.0153143.Peer-Reviewed Original ResearchConceptsIncident TB casesTB casesResistant TBDrug-resistant TB casesRifampicin-resistant tuberculosisMultidrug-resistant tuberculosisDrug susceptibility testingRIF-resistant TBLot Quality Assurance SamplingQuality assurance samplingResistant diseaseHigh burdenRIF resistanceKwaZulu-NatalSusceptibility testingHigh-risk areasTuberculosisRiskGreater proportionBurdenTBDiseaseGeographic heterogeneityCasesRifampicin
2015
Identifying Hotspots of Multidrug-Resistant Tuberculosis Transmission Using Spatial and Molecular Genetic Data
Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Manjourides J, Grenfell BT, Cohen T. Identifying Hotspots of Multidrug-Resistant Tuberculosis Transmission Using Spatial and Molecular Genetic Data. The Journal Of Infectious Diseases 2015, 213: 287-294. PMID: 26175455, PMCID: PMC4690150, DOI: 10.1093/infdis/jiv387.Peer-Reviewed Original ResearchConceptsMDR tuberculosisDrug susceptibilityTuberculosis casesMultidrug-resistant tuberculosis (MDR-TB) transmissionCulture-confirmed diseaseHealth Center areaProspective cohort studyCapita incidenceHousehold contactsCohort studyTuberculosis riskTuberculosis transmissionSymptomatic individualsHigh riskPositive culturesNumber tandem repeatRiskEtiology
2014
Geographical heterogeneity of multidrug-resistant tuberculosis in Georgia, January 2009 to June 2011.
Jenkins HE, Gegia M, Furin J, Kalandadze I, Nanava U, Chakhaia T, Cohen T. Geographical heterogeneity of multidrug-resistant tuberculosis in Georgia, January 2009 to June 2011. Eurosurveillance 2014, 19 PMID: 24679722, PMCID: PMC4090679, DOI: 10.2807/1560-7917.es2014.19.11.20743.Peer-Reviewed Original ResearchConceptsMultidrug-resistant TBMDR-TB risk factorsTB casesRisk factorsMDR-TB incidenceMDR-TB riskMDR-TB transmissionMDR-TB casesMultidrug-resistant tuberculosisTreatment-naïve individualsMDR-TB burdenTuberculosis casesHigh riskTargeted interventionsSurveillance dataGeographical heterogeneityRegression modellingInterventionRiskRural areasCasesTuberculosisIncidencePercentageHigh risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova.
Jenkins HE, Crudu V, Soltan V, Ciobanu A, Domente L, Cohen T. High risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova. European Respiratory Journal 2014, 43: 1132-41. PMID: 24558181, PMCID: PMC4005038, DOI: 10.1183/09031936.00203613.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisMDR-TB diagnosisMDR-TB casesTB treatmentFirst-line TB drugsAmbulatory TB treatmentMDR-TB riskDrug susceptibility testingNosocomial transmissionInitial diagnosisPercentage of individualsTB drugsTuberculosis treatmentEarly treatmentHigh riskSputum specimensSurveillance databasePrevious incarcerationDrug resistanceMultidrug resistanceDiagnosisTreatmentBaseline resistanceRapid appearanceRisk
2013
Disease Mapping with Spatially Uncertain Data
Manjourides J, Cohen T, Jeffery C, Pagano M. Disease Mapping with Spatially Uncertain Data. Online Journal Of Public Health Informatics 2013, 5 PMCID: PMC3692831, DOI: 10.5210/ojphi.v5i1.4380.Peer-Reviewed Original ResearchNew TB casesDrug sensitivity testingTB casesProgrammatic dataHigh TB burdenDrug-resistant casesTB burdenIncident casesResistant casesUnderlying burdenHigh riskRoutine dataDisease acquisitionInverse probabilityTransmission hotspotsSensitivity testingNon-random sampleRiskLocation of casesReduced testingDiseaseRepresentative sampleUnadjusted dataDRTBUntested cases
2012
Assessing spatial heterogeneity of multidrug-resistant tuberculosis in a high-burden country
Jenkins HE, Plesca V, Ciobanu A, Crudu V, Galusca I, Soltan V, Serbulenco A, Zignol M, Dadu A, Dara M, Cohen T. Assessing spatial heterogeneity of multidrug-resistant tuberculosis in a high-burden country. European Respiratory Journal 2012, 42: 1291-1301. PMID: 23100496, PMCID: PMC3800490, DOI: 10.1183/09031936.00111812.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisMDR-TB riskMDR-TB risk factorsNational TB surveillance dataMDR-TB incidenceTB surveillance dataMDR-TB casesHigh-burden countriesMDR-TB burdenDistribution of casesTB casesTuberculosis casesRisk of resistanceRisk factorsGreater riskSubstantial geographical variationSurveillance dataAppropriate targetingTesting coverageRiskTuberculosisBurdenHigh percentageLocal mechanismsPatientsIdentifying multidrug resistant tuberculosis transmission hotspots using routinely collected data
Manjourides J, Lin HH, Shin S, Jeffery C, Contreras C, Santa Cruz J, Jave O, Yagui M, Asencios L, Pagano M, Cohen T. Identifying multidrug resistant tuberculosis transmission hotspots using routinely collected data. Tuberculosis 2012, 92: 273-279. PMID: 22401962, PMCID: PMC3323731, DOI: 10.1016/j.tube.2012.02.003.Peer-Reviewed Original ResearchConceptsDrug sensitivity testTransmission hotspotsRetreatment casesDrug-resistant tuberculosis epidemicRisk of MDRTime of diagnosisDrug-resistant diseaseTB casesResistant diseaseTuberculosis epidemicHigh riskUntreated casesProgrammatic dataMDRTBRiskMDRHigh levelsTargeted investigationGeographic areasCasesDiseaseDiagnosisSensitivity tests