2024
Potential of Pan-Tuberculosis Treatment to Drive Emergence of Novel Resistance - Volume 30, Number 8—August 2024 - Emerging Infectious Diseases journal - CDC
McQuaid C, Ryckman T, Menzies N, White R, Cohen T, Kendall E. Potential of Pan-Tuberculosis Treatment to Drive Emergence of Novel Resistance - Volume 30, Number 8—August 2024 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2024, 30: 1571-1579. PMID: 39043388, PMCID: PMC11286077, DOI: 10.3201/eid3008.240541.Peer-Reviewed Original ResearchConceptsResistance to novel drugsStandard of careAntimicrobial resistanceIncreasing prevalence of antimicrobial resistancePrevalence of antimicrobial resistanceIncreased prevalenceDrug susceptibility testingCompare treatment outcomesFirst-line drugsNovel drugsTB patient cohortTreatment regimensPatient cohortNew tuberculosisRegimensTreatment outcomesComponent drugsDrugCohortTuberculosisCDCUniversal useClinicCarePrevalence
2018
The impact of digital health technologies on tuberculosis treatment: a systematic review
Ngwatu B, Nsengiyumva N, Oxlade O, Mappin-Kasirer B, Nguyen N, Jaramillo E, Falzon D, Schwartzman K, Abubakar I, Alipanah N, Bastos M, Boccia D, Chin D, Cohen T, Davis J, Denkinger C, Falzon D, Fielding K, Fox G, Free C, Garfein R, Hayward A, Jaramillo E, Lester R, Lewis J, Mappin-Kasirer B, Marx F, Menzies D, Migliori G, Nahid P, Ngwatu B, Nsengiyumva N, Nguyen N, Oxlade O, Schwartzman K, Siddiqi K, Story A, Thomas B, Trajman A, Yassin M. The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal 2018, 51: 1701596. PMID: 29326332, PMCID: PMC5764088, DOI: 10.1183/13993003.01596-2017.Peer-Reviewed Original ResearchConceptsVideo-observed therapyMedication monitorsStandard careObservational studyTreatment completion ratesTB treatment adherenceProbability of cureTreatment of personsPerson DOTActive tuberculosisTB careClinical outcomesTreatment adherenceTuberculosis treatmentPatient outcomesTreatment completionControl groupTreatment dosesSystematic reviewDigital health technologiesShort message serviceEffect estimatesTuberculosisDigital interventionsCare
2017
Catastrophic costs potentially averted by tuberculosis control in India and South Africa: a modelling study
Verguet S, Riumallo-Herl C, Gomez GB, Menzies NA, Houben RMGJ, Sumner T, Lalli M, White RG, Salomon JA, Cohen T, Foster N, Chatterjee S, Sweeney S, Baena IG, Lönnroth K, Weil DE, Vassall A. Catastrophic costs potentially averted by tuberculosis control in India and South Africa: a modelling study. The Lancet Global Health 2017, 5: e1123-e1132. PMID: 29025634, PMCID: PMC5640802, DOI: 10.1016/s2214-109x(17)30341-8.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisEnd TB StrategyTuberculosis servicesCatastrophic costsTB StrategyDrug-sensitive tuberculosisCatastrophic financial burdenAnnual household incomeTuberculosis careTuberculosis controlEconomic burdenTuberculosisIntervention effectsMelinda Gates FoundationHousehold incomeIndirect costsFinancial burdenExpansion of accessPatientsTotal annual household incomeTreatmentCareGates FoundationBurdenIntervention scenarios
2015
How could preventive therapy affect the prevalence of drug resistance? Causes and consequences
Kunkel A, Colijn C, Lipsitch M, Cohen T. How could preventive therapy affect the prevalence of drug resistance? Causes and consequences. Philosophical Transactions Of The Royal Society B Biological Sciences 2015, 370: 20140306. PMID: 25918446, PMCID: PMC4424438, DOI: 10.1098/rstb.2014.0306.Peer-Reviewed Original ResearchConceptsPreventative therapyDrug resistanceDrug-sensitive pathogensProphylactic antimicrobial therapyLong-term prevalenceSmall pilot studyActive diseaseOverall prevalenceAntimicrobial therapyPrevalencePilot studyTherapyPopulation-level changesPotential population-level effectsDirect effectLevel of coveragePopulation-level effectsHIVTuberculosisMalariaDiseaseCare
2011
Tuberculosis Among Participants in an Academic Global Health Medical Exchange Program
Gardner A, Cohen T, Carter EJ. Tuberculosis Among Participants in an Academic Global Health Medical Exchange Program. Journal Of General Internal Medicine 2011, 26: 841-845. PMID: 21359579, PMCID: PMC3138970, DOI: 10.1007/s11606-011-1669-x.Peer-Reviewed Original ResearchConceptsDirect medical careTST conversionTB infectionBurden countriesMedical careLow tuberculosis (TB) burden countriesTuberculin skin test conversionSkin test conversionTB endemic areasPre-travel preparationTuberculosis burden countriesHigh-burden countriesLength of stayTB educationTB preventionTB screeningTB testingTest conversionPercentage reportingDevelopment of guidelinesInadequate preDemographic characteristicsLonger durationExchange programsCare