Longitudinal Trajectories of Premorbid Social and Academic Adjustment in Youth at Clinical High Risk for Psychosis: Implications for Conversion
Cowan H, Mittal V, Addington J, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Woods S, Cannon T, Walker E. Longitudinal Trajectories of Premorbid Social and Academic Adjustment in Youth at Clinical High Risk for Psychosis: Implications for Conversion. Schizophrenia Bulletin 2024, sbae050. PMID: 38706103, DOI: 10.1093/schbul/sbae050.Peer-Reviewed Original ResearchConversion to psychosisClinical high riskAcademic adjustmentPremorbid periodPremorbid adjustmentNegative symptomsNon-convertersSocial adjustmentLongitudinal trajectoriesChildhood trauma impactsPremorbid adjustment trajectoriesPremorbid social functioningPoor academic adjustmentBetween-person levelPsychotic disorder diagnosisNon-affective psychosisPoor social adjustmentGrowth curve modelsPsychotic disordersPremorbid functioningChildhood traumaDisorder diagnosisCognitive effectsPsychosisAdjustment problemsThe Hierarchical Taxonomy of Psychopathology in Clinical High Risk for Psychosis: Validation and Extension
Williams T, Williams A, Cowan H, Walker E, Cannon T, Bearden C, Keshavan M, Cornblatt B, Addington J, Woods S, Perkins D, Mathalon D, Cadenhead K, Stone W, Mittal V. The Hierarchical Taxonomy of Psychopathology in Clinical High Risk for Psychosis: Validation and Extension. Journal Of Psychopathology And Clinical Science 2024, 133: 235-244. PMID: 38546628, PMCID: PMC11273326, DOI: 10.1037/abn0000893.Peer-Reviewed Original ResearchConceptsHierarchical Taxonomy of PsychopathologyTaxonomy of PsychopathologyClinical high riskHiTOP modelCHR-PChildhood traumaDimensional models of psychopathologyHierarchical taxonomyModels of psychopathologyAttenuated psychotic symptomsBipolar spectrum disordersObsessive-compulsive disorderCHR-P individualsConfirmatory factor analysisPsychotic symptomsPsychotic disordersComorbid diagnosesHiTOPSpectrum disorderPsychosisPsychopathologySocial functioningSelf-reportSpecific hypothesesTest specific hypotheses