2023
Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction
Brush J, Chaudhry S, Dreyer R, D'Onofrio G, Greene E, Hajduk A, Lu Y, Krumholz H. Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction. The American Journal Of Cardiology 2023, 197: 101-107. PMID: 37062667, PMCID: PMC10198892, DOI: 10.1016/j.amjcard.2023.03.009.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionD2B timeSymptom complexityYoung womenChest painBalloon timeST-elevation myocardial infarctionSILVER-AMI StudySymptom phenotypeSex differencesPain symptomsCoronary interventionOlder patientsMyocardial infarctionOlder womenSTEMIOlder menSymptom patternsPresentation delayPatientsSymptom clustersLogistic regressionSymptomsWomenMean numberGender Disparity in National Institutes of Health Funding Among Surgeon-Scientists From 1995 to 2020
Nguyen M, Gonzalez L, Chaudhry S, Ahuja N, Pomahac B, Newman A, Cannon A, Zarebski S, Dardik A, Boatright D. Gender Disparity in National Institutes of Health Funding Among Surgeon-Scientists From 1995 to 2020. JAMA Network Open 2023, 6: e233630. PMID: 36939702, PMCID: PMC10028489, DOI: 10.1001/jamanetworkopen.2023.3630.Peer-Reviewed Original ResearchConceptsCross-sectional studyNIH fundingNational InstitutePatient-centered researchNIH RePORTER databaseWarrants further investigationPrincipal investigatorSurgical diseaseGlobal burdenMAIN OUTCOMEResearch project grantsSurgeonsWomenHealth fundingAcademic surgeonsMenNIH grantsDiseaseFurther investigationGender, Racial, and Ethnic and Inequities in Receipt of Multiple National Institutes of Health Research Project Grants
Nguyen M, Chaudhry S, Desai M, Dzirasa K, Cavazos J, Boatright D. Gender, Racial, and Ethnic and Inequities in Receipt of Multiple National Institutes of Health Research Project Grants. JAMA Network Open 2023, 6: e230855. PMID: 36853608, PMCID: PMC9975935, DOI: 10.1001/jamanetworkopen.2023.0855.Peer-Reviewed Original ResearchConceptsCross-sectional studyResearch project grantsNational cohortHealth Research Project GrantPrincipal investigatorNational InstituteComplex health problemsWarrants further investigationNIH investigatorsProject grantsRacial groupsMAIN OUTCOMEEarly-stage investigatorsHealth problemsRacial distributionHealth investigatorsNIH grantsAnnual numberCohort
2022
A risk model for decline in health status after acute myocardial infarction among older adults
Hajduk A, Dodson J, Murphy T, Chaudhry S. A risk model for decline in health status after acute myocardial infarction among older adults. Journal Of The American Geriatrics Society 2022, 71: 1228-1235. PMID: 36519774, PMCID: PMC10089939, DOI: 10.1111/jgs.18162.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth status declineImportant patient-centered outcomesPatient-centered outcomesMyocardial infarctionStatus declineHealth statusOlder adultsShort Form-12 Physical Component ScorePhysical component scoreProspective cohort studyRisk prediction modelLogistic regression modelsOlder adult survivorsPredictive risk modelRisk modelCohort studyPatient ageValidation cohortC-statisticRisk factorsHigh riskLower riskAdult survivorsHospitalizationRacial and Ethnic Differences in Internal Medicine Residency Assessments
Boatright D, Anderson N, Kim J, Holmboe E, McDade W, Fancher T, Gross C, Chaudhry S, Nguyen M, Tiako M, Colson E, Xu Y, Li F, Dziura J, Saha S. Racial and Ethnic Differences in Internal Medicine Residency Assessments. JAMA Network Open 2022, 5: e2247649. PMID: 36580337, PMCID: PMC9857126, DOI: 10.1001/jamanetworkopen.2022.47649.Peer-Reviewed Original ResearchRacial disparities among older adults with acute myocardial infarction: The SILVER‐AMI study
Demkowicz P, Hajduk A, Dodson J, Oladele C, Chaudhry S. Racial disparities among older adults with acute myocardial infarction: The SILVER‐AMI study. Journal Of The American Geriatrics Society 2022, 71: 474-483. PMID: 36415964, PMCID: PMC9957871, DOI: 10.1111/jgs.18084.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionFunctional impairmentGeriatric conditionsClinical characteristicsMyocardial infarctionBlack participantsOlder adultsRacial disparitiesRisk of mortalityMore functional impairmentSILVER-AMI StudyBlack older adultsYounger average ageUnadjusted oddsDaily livingAMI hospitalizationAverage ageGeriatric phenotypesUS hospitalsHospitalizationLogistic regressionMortalityImpairmentInfarctionUnintentional lossVariation in Research Experiences and Publications During Medical School by Sex and Race and Ethnicity
Nguyen M, Chaudhry SI, Asabor E, Desai MM, Lett E, Cavazos JE, Mason HRC, Boatright D. Variation in Research Experiences and Publications During Medical School by Sex and Race and Ethnicity. JAMA Network Open 2022, 5: e2238520. PMID: 36282497, PMCID: PMC9597391, DOI: 10.1001/jamanetworkopen.2022.38520.Peer-Reviewed Original ResearchAssociation of Marginalized Identities With Alpha Omega Alpha Honor Society and Gold Humanism Honor Society Membership Among Medical Students
Hill KA, Desai MM, Chaudhry SI, Nguyen M, McDade W, Xu Y, Li F, Fancher T, Hajduk AM, Westervelt MJ, Boatright D. Association of Marginalized Identities With Alpha Omega Alpha Honor Society and Gold Humanism Honor Society Membership Among Medical Students. JAMA Network Open 2022, 5: e2229062. PMID: 36069984, PMCID: PMC9453541, DOI: 10.1001/jamanetworkopen.2022.29062.Peer-Reviewed Original ResearchConceptsIntersections of identitySexual orientationLGB studentsHeterosexual studentsWhite studentsFamily incomeMarginalized groupsStudent raceMarginalized identityAmerican IndiansMultiracial studentsDifferent identitiesAlaska NativesAsian studentsIdentityMembershipSocietyPacific IslandersRaceEthnicityIncomeIntersectionData collection instrumentSociety membershipNativesAssociation of Sociodemographic Characteristics With US Medical Student Attrition
Nguyen M, Chaudhry SI, Desai MM, Chen C, Mason HRC, McDade WA, Fancher TL, Boatright D. Association of Sociodemographic Characteristics With US Medical Student Attrition. JAMA Internal Medicine 2022, 182: 917-924. PMID: 35816334, PMCID: PMC9274446, DOI: 10.1001/jamainternmed.2022.2194.Peer-Reviewed Original ResearchConceptsRetrospective cohort studyCohort studyMAIN OUTCOMELow incomeHealth care accessPatient populationResource-limited communitiesCare accessAllopathic doctorsMedical schoolsSignificant associationSociodemographic characteristicsLogistic regressionRate of attritionPhysician workforceMedical school matriculantsMedical traineesMedical workforceAttrition ratesOutcomesNon-Hispanic white studentsAssociationNeighbourhood statusAttritionAssociations between hospitalist physician workload, length of stay, and return to the hospital
Djulbegovic M, Chen K, Cohen AB, Heacock D, Canavan M, Cushing W, Agarwal R, Simonov M, Chaudhry SI. Associations between hospitalist physician workload, length of stay, and return to the hospital. Journal Of Hospital Medicine 2022, 17: 445-455. PMID: 35662410, PMCID: PMC9248905, DOI: 10.1002/jhm.12847.Peer-Reviewed Original ResearchConceptsLength of stayEmergency departmentPhysician workloadYale-New Haven HospitalMedian patient ageSeverity of illnessElectronic health record dataNumber of patientsHealth record dataWeekend admissionHospital daysPatient ageClinical outcomesObservational studyHospitalist serviceMAIN OUTCOMEPatient complexityHospitalist workloadSociodemographic factorsPatient encountersPatientsLogistic regressionMultilevel PoissonRecord dataOutcomes
2021
Sex Differences in Symptom Phenotypes Among Older Patients with Acute Myocardial Infarction
Brush JE, Hajduk AM, Greene EJ, Dreyer RP, Krumholz HM, Chaudhry SI. Sex Differences in Symptom Phenotypes Among Older Patients with Acute Myocardial Infarction. The American Journal Of Medicine 2021, 135: 342-349. PMID: 34715061, PMCID: PMC8901454, DOI: 10.1016/j.amjmed.2021.09.022.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionSymptom combinationsOlder patientsAcute myocardial infarction subgroupsAcute myocardial infarction admissionsMyocardial infarction subgroupsPatients 75 yearsMyocardial infarction admissionsSILVER-AMI StudySymptom phenotypeClinical studiesIndividual patientsMore symptomsPatientsInfarctionDiagnostic possibilitiesSymptomsWomenPerson interviewsMenCommon phenotypeSex differencesCliniciansPhenotypePresentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study
Hajduk AM, Saczynski JS, Tsang S, Geda ME, Dodson JA, Ouellet GM, Goldberg RJ, Chaudhry SI. Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study. The American Journal Of Medicine 2021, 134: 910-917. PMID: 33737057, PMCID: PMC8243828, DOI: 10.1016/j.amjmed.2021.03.003.Peer-Reviewed Original ResearchConceptsSevere cognitive impairmentAcute myocardial infarctionMyocardial infarctionCognitive impairmentOlder acute myocardial infarction patientsCognitive statusMultivariable-adjusted logistic regressionAcute myocardial infarction patientsOlder adultsRoutine cognitive screeningRisk of readmissionMedical record reviewRisk of deathPost-discharge periodMyocardial infarction patientsMyocardial infarction survivorsSILVER-AMI StudyComorbidity burdenHospital readmissionPoor outcomeRecord reviewFunctional statusInfarction patientsUnadjusted analysesInfarction survivors180-day readmission risk model for older adults with acute myocardial infarction: the SILVER-AMI study
Dodson JA, Hajduk AM, Murphy TE, Geda M, Krumholz HM, Tsang S, Nanna MG, Tinetti ME, Ouellet G, Sybrant D, Gill TM, Chaudhry SI. 180-day readmission risk model for older adults with acute myocardial infarction: the SILVER-AMI study. Open Heart 2021, 8: e001442. PMID: 33452007, PMCID: PMC7813425, DOI: 10.1136/openhrt-2020-001442.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionReadmission risk modelSelf-reported health statusMyocardial infarctionFunctional mobilityOlder adultsHealth statusDays of AMIFirst diastolic blood pressureChronic obstructive pulmonary diseaseIschemic ECG changesProspective cohort studyDiastolic blood pressureObstructive pulmonary diseaseLength of stayInitial heart rateFinal risk modelSILVER-AMI StudyRisk modelInitial hemoglobinCohort studyReadmission ratesBlood pressureEjection fractionHeart failure
2020
Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study
Hajduk AM, Dodson JA, Murphy TE, Tsang S, Geda M, Ouellet GM, Gill TM, Brush JE, Chaudhry SI. Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study. Journal Of The American Heart Association 2020, 9: e015555. PMID: 33000681, PMCID: PMC7792390, DOI: 10.1161/jaha.119.015555.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionDaily living declineSILVER-AMI StudyDaily livingOlder patientsMonths postdischargeMyocardial infarctionFunctional declineImportant patient-centered outcomesPoor long-term outcomesLonger hospital stayLong-term outcomesPatient-centered outcomesGeriatric impairmentsHospital stayAMI survivorsClinical variablesMean ageMedical recordsRisk factorsRestorative therapyPhysical activityAMI hospitalizationPsychosocial factorsUS hospitalsThe Association Between Hospital End-of-Life Care Quality and the Care Received Among Patients With Heart Failure
Feder SL, Tate J, Ersek M, Krishnan S, Chaudhry SI, Bastian LA, Rolnick J, Kutney-Lee A, Akgün KM. The Association Between Hospital End-of-Life Care Quality and the Care Received Among Patients With Heart Failure. Journal Of Pain And Symptom Management 2020, 61: 713-722.e1. PMID: 32931904, PMCID: PMC7952458, DOI: 10.1016/j.jpainsymman.2020.09.006.Peer-Reviewed Original ResearchConceptsHeart failure patientsPalliative care consultationVeterans Health AdministrationLife care qualityFailure patientsHeart failureCare consultationsHighest quintileVA hospitalsIntensive care unit deathCare qualityIntensive care unitHealth care systemCare unitInpatient hospiceMean ageLowest quintileHospital endRetrospective analysisHOSPITAL scorePatientsHealth AdministrationCare processesHospitalLogistic regressionPresentation, Treatment, and Outcomes of the Oldest-Old Patients with Acute Myocardial Infarction: The SILVER-AMI Study
Gupta A, Tsang S, Hajduk A, Krumholz HM, Nanna MG, Green P, Dodson JA, Chaudhry SI. Presentation, Treatment, and Outcomes of the Oldest-Old Patients with Acute Myocardial Infarction: The SILVER-AMI Study. The American Journal Of Medicine 2020, 134: 95-103. PMID: 32805225, PMCID: PMC7752813, DOI: 10.1016/j.amjmed.2020.07.020.Peer-Reviewed Original ResearchConceptsOldest-old patientsMyocardial infarctionFunctional impairmentOlder patientsMobility impairmentsCox proportional hazards regressionMiddle-old patientsProportional hazards regressionAcute myocardial infarctionCase fatality rateAcute myocardial infarction hospitalizationsSILVER-AMI StudyYears of ageMyocardial infarction hospitalizationsChest painCoronary revascularizationAtypical presentationHazards regressionClinical variablesRisk factorsAdvanced agePrimary symptomsPatientsFatality rateHealth statusAssociation between emergency department chief complaint and adverse hospitalization outcomes: A simple early warning system?
Lord K, Rothenberg C, Parwani V, Finn E, Khan A, Sather J, Ulrich A, Chaudhry S, Venkatesh A. Association between emergency department chief complaint and adverse hospitalization outcomes: A simple early warning system? The American Journal Of Emergency Medicine 2020, 45: 548-550. PMID: 32839053, DOI: 10.1016/j.ajem.2020.07.040.Peer-Reviewed Original ResearchPatient and Cardiologist Perspectives on Shared Decision Making in the Treatment of Older Adults Hospitalized for Acute Myocardial Infarction
Grant EV, Summapund J, Matlock DD, Dickson V, Iqbal S, Patel S, Katz SD, Chaudhry SI, Dodson JA. Patient and Cardiologist Perspectives on Shared Decision Making in the Treatment of Older Adults Hospitalized for Acute Myocardial Infarction. Medical Decision Making 2020, 40: 279-288. PMID: 32428431, PMCID: PMC8684600, DOI: 10.1177/0272989x20912293.Peer-Reviewed Original ResearchConceptsST-elevated myocardial infarctionAcute myocardial infarctionMyocardial infarctionOlder adultsCardiologist's perspectiveOlder patientsSetting of AMIElevated myocardial infarctionPatient-specific riskConcept of SDMCardiologists' perceptionsMajor contraindicationPatient ageSuch patientsInterventional therapyFunctional limitationsInvasive proceduresPatientsInfarctionCognitive impairmentCardiologistsAdultsRiskConstant comparative methodTeam-based process
2019
Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study.
Dodson JA, Hajduk AM, Geda M, Krumholz HM, Murphy TE, Tsang S, Tinetti ME, Nanna MG, McNamara R, Gill TM, Chaudhry SI. Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. Annals Of Internal Medicine 2019, 172: 12-21. PMID: 31816630, PMCID: PMC7695040, DOI: 10.7326/m19-0974.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPost-AMI mortalityFunctional impairmentOlder adultsCohort studyMean ageMyocardial infarctionPatient-reported health statusNet reclassification improvement indexProspective cohort studyParticipants' mean ageFinal risk modelMobility impairmentsGood discriminatory abilityRisk modelChart reviewHospital dischargePrognostic utilityBlood InstituteClinical variablesNational HeartHigh prevalenceHealth statusMortalityYounger counterpartsUsefulness of Social Support in Older Adults After Hospitalization for Acute Myocardial Infarction (from the SILVER-AMI Study)
Green YS, Hajduk AM, Song X, Krumholz HM, Sinha SK, Chaudhry SI. Usefulness of Social Support in Older Adults After Hospitalization for Acute Myocardial Infarction (from the SILVER-AMI Study). The American Journal Of Cardiology 2019, 125: 313-319. PMID: 31787249, PMCID: PMC7003680, DOI: 10.1016/j.amjcard.2019.10.038.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPost-AMI outcomesMyocardial infarctionIndependent associationMedical Outcomes Study Social Support SurveySocial supportOlder AMI patientsSocial Support SurveyParticipants 75 yearsLow emotional supportLow social supportImportant social determinantInitial hospitalizationOlder patientsDevelopment of interventionsAMI patientsMultivariable analysisMean ageMultivariable regressionHealth outcomesSupport SurveyInformational supportReadmissionSocial determinantsOlder adults