Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence
Morgan PT, Angarita GA, Canavan S, Pittman B, Oberleitner L, Malison RT, Mohsenin V, Hodges S, Easton C, McKee S, Bessette A, Forselius E. Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence. Drug And Alcohol Dependence 2016, 160: 49-56. PMID: 26777774, PMCID: PMC4767553, DOI: 10.1016/j.drugalcdep.2015.12.004.Peer-Reviewed Original ResearchConceptsUrine toxicology screenModafinil treatmentSlow-wave sleepClinical outcomesOutpatient treatmentToxicology screenUrine screensInpatient settingInpatient treatmentSleep timeCocaine dependencePrimary clinical outcomeWeekly cognitive behavioral therapyCocaine usersImproved clinical outcomesPolysomnographic sleep recordingsChronic cocaine useChronic cocaine usersHigh rateCognitive behavioral therapyCocaine-dependent participantsSleep architectureOutpatient phaseEffective treatmentDays abstinentChapter 21 Sleep and Cocaine
Angarita G, Canavan S, Hodges S, Morgan P. Chapter 21 Sleep and Cocaine. 2016, 220-228. DOI: 10.1016/b978-0-12-800212-4.00021-2.Peer-Reviewed Original ResearchPoor cognitive performanceChronic cocaine usersChapter 21 SleepObjective sleep abnormalitiesCocaine use disorderOccult insomniaCognitive performanceSleep architectureMood dysregulationSleep experiencesCocaine usersAbstinenceSleepSleep abnormalitiesInsomniaCocaineDisordersOutcomesExperienceDysregulationBetter outcomesProfound abnormalities