2024
Brain Care Score and Neuroimaging Markers of Brain Health in Asymptomatic Middle-Age Persons
Rivier C, Singh S, Senff J, Tack R, Marini S, Clocchiatti-Tuozzo S, Huo S, Renedo D, Papier K, Conroy M, Littlejohns T, Chemali Z, Kourkoulis C, Payabvash S, Newhouse A, Westover M, Lazar R, Pikula A, Ibrahim S, Howard V, Howard G, Brouwers H, Van Duijn C, Fricchione G, Tanzi R, Yechoor N, Sheth K, Anderson C, Rosand J, Falcone G. Brain Care Score and Neuroimaging Markers of Brain Health in Asymptomatic Middle-Age Persons. Neurology 2024, 103: e209687. PMID: 39052961, DOI: 10.1212/wnl.0000000000209687.Peer-Reviewed Original ResearchConceptsCare scoresUK BiobankWhite matter hyperintensitiesHealth-related behaviorsMarkers of brain healthMiddle-aged personsStroke risk factorsProspective cohort studyMultivariate linear regressionEmpower patientsSilent cerebrovascular diseaseBrain careWhite matter hyperintensities progressionDementia historyHealth declineInvestigate associationsCohort studyBrain healthNeuroimaging markersHigher scoresRisk factorsMean diffusivityCerebrovascular diseaseFractional anisotropyImaging assessment
2023
Suboptimal Sleep Duration Is Associated With Poorer Neuroimaging Brain Health Profiles in Middle‐Aged Individuals Without Stroke or Dementia
Clocchiatti‐Tuozzo S, Rivier C, Renedo D, Lopez V, Geer J, Miner B, Yaggi H, de Havenon A, Payabvash S, Sheth K, Gill T, Falcone G. Suboptimal Sleep Duration Is Associated With Poorer Neuroimaging Brain Health Profiles in Middle‐Aged Individuals Without Stroke or Dementia. Journal Of The American Heart Association 2023, 13: e031514. PMID: 38156552, PMCID: PMC10863828, DOI: 10.1161/jaha.123.031514.Peer-Reviewed Original ResearchConceptsSuboptimal sleep durationWhite matter hyperintensitiesMiddle-aged individualsLong sleep durationLarger WMH volumeSleep durationMiddle-aged adultsHealth profileWMH volumeAmerican Heart Association's LifeAsymptomatic middle-aged adultsWMH presenceVolume of WMHOptimal sleepSelf-reported sleep durationModifiable risk factorsWhite matter tractsProspective magnetic resonanceSimple 7Cardiovascular healthRisk factorsShort sleepMatter hyperintensitiesHigh riskEarly interventionIdentification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging
de Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesMagnetic resonance imagingSevere white matter hyperintensitiesConventional magnetic resonance imagingResonance imagingRetrospective cohortEmergency departmentMatter hyperintensitiesVascular risk factorsProspective observational studyVascular cognitive impairmentTesla magnetic resonance imagingArea Deprivation IndexProspective cohortAdult patientsAcute careRisk factorsCardiovascular diseaseObservational studyCognitive impairmentPatientsCare magnetic resonance imagingIntermodality agreementCohortDeprivation indexBlood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults
Acosta J, Haider S, Rivier C, Leasure A, Sheth K, Falcone G, Payabvash S. Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults. Stroke And Vascular Neurology 2023, 8: 358-367. PMID: 36878613, PMCID: PMC10647862, DOI: 10.1136/svn-2022-001929.Peer-Reviewed Original Research
2022
Analysis of Clinical Traits Associated With Cardiovascular Health, Genomic Profiles, and Neuroimaging Markers of Brain Health in Adults Without Stroke or Dementia
Acosta JN, Both CP, Rivier C, Szejko N, Leasure AC, Gill TM, Payabvash S, Sheth KN, Falcone GJ. Analysis of Clinical Traits Associated With Cardiovascular Health, Genomic Profiles, and Neuroimaging Markers of Brain Health in Adults Without Stroke or Dementia. JAMA Network Open 2022, 5: e2215328. PMID: 35622359, PMCID: PMC9142873, DOI: 10.1001/jamanetworkopen.2022.15328.Peer-Reviewed Original ResearchConceptsBrain healthBrain volumeMagnetic resonance imagingLower mean volumeLifestyle factorsCardiovascular healthLarge population-based cohort studyLife's Simple 7 (LS7) scoresPopulation-based cohort studyBrain magnetic resonance imagingMean volumeWhite matter hyperintensity volumeBrain health benefitsCommunity-dwelling personsImproved brain healthOutcomes of interestUK BiobankFinal analytical sampleAsymptomatic personsCohort studyLS7 scoreNeuroimaging markerHyperintensity volumeMAIN OUTCOMEGenetic predisposition
2020
Choice of imaging modality for pre-treatment staging of head and neck cancer impacts TNM staging
Mur T, Sambhu KM, Mahajan A, Payabvash S, Fernandez J, Edwards HA. Choice of imaging modality for pre-treatment staging of head and neck cancer impacts TNM staging. American Journal Of Otolaryngology 2020, 41: 102662. PMID: 32858370, DOI: 10.1016/j.amjoto.2020.102662.Peer-Reviewed Original ResearchConceptsPET/CTLow-dose nonenhanced CTDistant metastasisChest CTNeck cancerNonenhanced CTF-fluorodeoxyglucose positron emission tomographyF-FDG PET/CTDiagnostic chest CTDistant metastatic diseaseInitiation of therapyRetrospective cohort studyPre-treatment stagingTertiary care settingSignificant differencesPositron emission tomographyMetastatic diseaseCohort studyOncologic treatmentTNM stagingInaccurate stagingNeck radiologistsCare settingsSingle patientPatients
2018
Volumetric voxelwise apparent diffusion coefficient histogram analysis for differentiation of the fourth ventricular tumors
Payabvash S, Tihan T, Cha S. Volumetric voxelwise apparent diffusion coefficient histogram analysis for differentiation of the fourth ventricular tumors. The Neuroradiology Journal 2018, 31: 554-564. PMID: 30230411, PMCID: PMC6243467, DOI: 10.1177/1971400918800803.Peer-Reviewed Original ResearchDifferentiation of Cerebellar Hemisphere Tumors: Combining Apparent Diffusion Coefficient Histogram Analysis and Structural MRI Features
Payabvash S, Tihan T, Cha S. Differentiation of Cerebellar Hemisphere Tumors: Combining Apparent Diffusion Coefficient Histogram Analysis and Structural MRI Features. Journal Of Neuroimaging 2018, 28: 656-665. PMID: 30066449, DOI: 10.1111/jon.12550.Peer-Reviewed Original Research
2016
Prominent cortical and medullary veins on susceptibility-weighted images of acute ischaemic stroke
Payabvash S, Benson JC, Taleb S, Rykken JB, Hoffman B, Oswood MC, McKinney AM. Prominent cortical and medullary veins on susceptibility-weighted images of acute ischaemic stroke. British Journal Of Radiology 2016, 89: 20160714. PMID: 27805839, PMCID: PMC5604931, DOI: 10.1259/bjr.20160714.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeLarger infarct volumesMedullary veinsIschemic strokeInfarct volumeArterial occlusionSusceptibility-weighted imagesConsecutive patientsClinical outcomesCortical veinsProminent cortical veinsPosterior circulation territoryPoor clinical outcomeSeverity of symptomsFair interobserver agreementSWI seriesAcute strokeSymptom onsetIndependent predictorsClinical variablesSWI scansPatientsStrokeImaging implicationsProminent veinsCT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location
Benson JC, Payabvash S, Mortazavi S, Zhang L, Salazar P, Hoffman B, Oswood M, McKinney AM. CT Perfusion in Acute Lacunar Stroke: Detection Capabilities Based on Infarct Location. American Journal Of Neuroradiology 2016, 37: 2239-2244. PMID: 27538902, PMCID: PMC7963880, DOI: 10.3174/ajnr.a4904.Peer-Reviewed Original Research
2014
Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy
Payabvash S, McKinney A, Nascene D, Cayci Z. Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy. Journal Of Postgraduate Medicine 2014, 60: 394-396. PMID: 25370549, DOI: 10.4103/0022-3859.143968.Peer-Reviewed Original Research
2013
Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients
Qian J, Payabvash S, Kemmling A, Lev MH, Schwamm LH, Betensky RA. Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients. Biometrics 2013, 70: 153-163. PMID: 24320930, PMCID: PMC3954429, DOI: 10.1111/biom.12113.Peer-Reviewed Original ResearchConceptsMassachusetts General HospitalCase-control studyStroke patientsAcute ischemic stroke patientsBrain regionsMatched Case-Control StudyHospital-Acquired PneumoniaIschemic stroke patientsLarge prospective studiesUnconditional logistic regressionCase-control designSpecific brain regionsAcquired PneumoniaAcute infarctionClinical featuresProspective studyClinical variablesGeneral HospitalEpidemiologic studiesPatientsModern imagingLarger studyLogistic regressionAppropriate statistical analysisHAP studiesScreening and detection of blunt vertebral artery injury in patients with upper cervical fractures: The role of cervical CT and CT angiography
Payabvash S, McKinney AM, McKinney ZJ, Palmer CS, Truwit CL. Screening and detection of blunt vertebral artery injury in patients with upper cervical fractures: The role of cervical CT and CT angiography. European Journal Of Radiology 2013, 83: 571-577. PMID: 24355656, DOI: 10.1016/j.ejrad.2013.11.020.Peer-Reviewed Original ResearchConceptsBlunt vertebral artery injuryVertebral artery injuryUpper cervical fracturesCervical fracturesSymptomatic strokeArtery injuryTrauma patientsBlunt trauma patientsPosterior circulation strokeScreening criteriaStrong interobserver agreementCervical CTCervical CTAUnderwent CTAClinical recordsNegative CTATransverse foramenCT angiographyCTA studiesClinical utilityPatientsInterobserver agreementC3-C7StrokeNECT
2011
Cranial CT with Adaptive Statistical Iterative Reconstruction: Improved Image Quality with Concomitant Radiation Dose Reduction
Rapalino O, Kamalian S, Kamalian S, Payabvash S, Souza LC, Zhang D, Mukta J, Sahani DV, Lev MH, Pomerantz SR. Cranial CT with Adaptive Statistical Iterative Reconstruction: Improved Image Quality with Concomitant Radiation Dose Reduction. American Journal Of Neuroradiology 2011, 33: 609-615. PMID: 22207302, PMCID: PMC8050448, DOI: 10.3174/ajnr.a2826.Peer-Reviewed Original ResearchConceptsHead CTRadiation dose reductionAdult head CTBlinded qualitative analysisHigh-dose onesUse of ASIRCT radiation dose reductionASIR levelsHounsfield unit measurementsAdult patientsLow-dose scansBrain parenchymaCranial CTRoutine doseLow radiation dosesDose reductionCT scanLow-dose CT datasetAdaptive statistical iterative reconstructionPatient healthASIR reconstructionNormal GMsCTDose scansGM-WM differentiationAdmission CT Perfusion Is an Independent Predictor of Hemorrhagic Transformation in Acute Stroke with Similar Accuracy to DWI
Souza LC, Payabvash S, Wang Y, Kamalian S, Schaefer P, Gonzalez RG, Furie KL, Lev MH. Admission CT Perfusion Is an Independent Predictor of Hemorrhagic Transformation in Acute Stroke with Similar Accuracy to DWI. Cerebrovascular Diseases 2011, 33: 8-15. PMID: 22143195, PMCID: PMC3250646, DOI: 10.1159/000331914.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBostonCerebrovascular CirculationChi-Square DistributionDiffusion Magnetic Resonance ImagingFemaleHumansIntracranial HemorrhagesLogistic ModelsMaleMiddle AgedMultivariate AnalysisPatient AdmissionPerfusion ImagingPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC CurveStrokeTomography, X-Ray ComputedConceptsRelative mean transit timeAdmission CT perfusionDiffusion-weighted imagingPredictors of HTRelative cerebral blood flowHemorrhagic transformationCT perfusionAcute strokeIndependent predictorsTissue volumeAdmission diffusion-weighted imagingConsecutive stroke patientsOnly independent predictorCerebral blood flowIschemic hemisphereMechanical thrombectomyStroke patientsInfarct coreMean transit timeBlood flowTest characteristicsCurve analysisDWI scansLesionsStrokeCT Cerebral Blood Flow Maps Optimally Correlate With Admission Diffusion-Weighted Imaging in Acute Stroke but Thresholds Vary by Postprocessing Platform
Kamalian S, Kamalian S, Maas MB, Goldmacher GV, Payabvash S, Akbar A, Schaefer PW, Furie KL, Gonzalez RG, Lev MH. CT Cerebral Blood Flow Maps Optimally Correlate With Admission Diffusion-Weighted Imaging in Acute Stroke but Thresholds Vary by Postprocessing Platform. Stroke 2011, 42: 1923-1928. PMID: 21546490, PMCID: PMC3125441, DOI: 10.1161/strokeaha.110.610618.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingCT perfusion parametersAcute strokeCT perfusionInfarct coreAdmission diffusion-weighted imagingPerfusion parametersCerebral blood flowCerebral blood flow mapsCerebral blood volumeCharacteristic curve analysisAdmission CT perfusionBlood flow mapsUninvolved hemisphere