2024
Brain Care Score and Neuroimaging Markers of Brain Health in Asymptomatic Middle-Age Persons
Rivier C, Singh S, Senff J, Tack R, Marini S, Clocchiatti-Tuozzo S, Huo S, Renedo D, Papier K, Conroy M, Littlejohns T, Chemali Z, Kourkoulis C, Payabvash S, Newhouse A, Westover M, Lazar R, Pikula A, Ibrahim S, Howard V, Howard G, Brouwers H, Van Duijn C, Fricchione G, Tanzi R, Yechoor N, Sheth K, Anderson C, Rosand J, Falcone G. Brain Care Score and Neuroimaging Markers of Brain Health in Asymptomatic Middle-Age Persons. Neurology 2024, 103: e209687. PMID: 39052961, DOI: 10.1212/wnl.0000000000209687.Peer-Reviewed Original ResearchConceptsCare scoresUK BiobankWhite matter hyperintensitiesHealth-related behaviorsMarkers of brain healthMiddle-aged personsStroke risk factorsProspective cohort studyMultivariate linear regressionEmpower patientsSilent cerebrovascular diseaseBrain careWhite matter hyperintensities progressionDementia historyHealth declineInvestigate associationsCohort studyBrain healthNeuroimaging markersHigher scoresRisk factorsMean diffusivityCerebrovascular diseaseFractional anisotropyImaging assessment
2023
Suboptimal Sleep Duration Is Associated With Poorer Neuroimaging Brain Health Profiles in Middle‐Aged Individuals Without Stroke or Dementia
Clocchiatti‐Tuozzo S, Rivier C, Renedo D, Lopez V, Geer J, Miner B, Yaggi H, de Havenon A, Payabvash S, Sheth K, Gill T, Falcone G. Suboptimal Sleep Duration Is Associated With Poorer Neuroimaging Brain Health Profiles in Middle‐Aged Individuals Without Stroke or Dementia. Journal Of The American Heart Association 2023, 13: e031514. PMID: 38156552, PMCID: PMC10863828, DOI: 10.1161/jaha.123.031514.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainDementiaHumansMagnetic Resonance ImagingMiddle AgedNeuroimagingProspective StudiesSleep DurationStrokeWhite MatterConceptsSuboptimal sleep durationWhite matter hyperintensitiesMiddle-aged individualsLong sleep durationLarger WMH volumeSleep durationMiddle-aged adultsHealth profileWMH volumeAmerican Heart Association's LifeAsymptomatic middle-aged adultsWMH presenceVolume of WMHOptimal sleepSelf-reported sleep durationModifiable risk factorsWhite matter tractsProspective magnetic resonanceSimple 7Cardiovascular healthRisk factorsShort sleepMatter hyperintensitiesHigh riskEarly interventionIdentification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging
de Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesRetrospective StudiesWhite MatterConceptsWhite matter hyperintensitiesMagnetic resonance imagingSevere white matter hyperintensitiesConventional magnetic resonance imagingResonance imagingRetrospective cohortEmergency departmentMatter hyperintensitiesVascular risk factorsProspective observational studyVascular cognitive impairmentTesla magnetic resonance imagingArea Deprivation IndexProspective cohortAdult patientsAcute careRisk factorsCardiovascular diseaseObservational studyCognitive impairmentPatientsCare magnetic resonance imagingIntermodality agreementCohortDeprivation index
2022
Bedside detection of intracranial midline shift using portable magnetic resonance imaging
Sheth KN, Yuen MM, Mazurek MH, Cahn BA, Prabhat AM, Salehi S, Shah JT, By S, Welch EB, Sofka M, Sacolick LI, Kim JA, Payabvash S, Falcone GJ, Gilmore EJ, Hwang DY, Matouk C, Gordon-Kundu B, RN AW, Petersen N, Schindler J, Gobeske KT, Sansing LH, Sze G, Rosen MS, Kimberly WT, Kundu P. Bedside detection of intracranial midline shift using portable magnetic resonance imaging. Scientific Reports 2022, 12: 67. PMID: 34996970, PMCID: PMC8742125, DOI: 10.1038/s41598-021-03892-7.Peer-Reviewed Original ResearchConceptsMidline shiftNeuroscience intensive care unitCare measurementYale-New Haven HospitalValuable bedside toolIntensive care unitPoor clinical outcomeBrain-injured patientsMass effectNew Haven HospitalMagnetic resonance imagingClinical outcomesIll patientsCare unitStroke patientsFunctional outcomeBedside toolObservational studyBedside detectionImaging examsPatientsResonance imagingPortable MRIImaging suiteSignificant concordance
2021
Rapid Assessment of Blood Pressure Variability and Outcome After Successful Thrombectomy
Castro P, Ferreira F, Nguyen CK, Payabvash S, Tan C, Sorond F, Azevedo E, Petersen N. Rapid Assessment of Blood Pressure Variability and Outcome After Successful Thrombectomy. Stroke 2021, 52: e531-e535. PMID: 34311565, PMCID: PMC8384685, DOI: 10.1161/strokeaha.121.034291.Peer-Reviewed Original ResearchMeSH KeywordsBlood PressureBrain IschemiaHumansHypertensionOdds RatioProspective StudiesStrokeThrombectomyTreatment OutcomeConceptsBlood pressure variabilityEndovascular stroke therapyBP variabilityFunctional outcomeNeurological recoveryStroke therapyPressure variabilityAnterior circulation ischemic strokeHigh blood pressure variabilityLong-term functional outcomeBP variability measuresEarly clinical improvementEarly neurological recoveryPersonalized BP managementFavorable functional outcomeInitial clinical responsePoor functional outcomeRisk assessment toolSuccessful reperfusionClinical improvementClinical responseIschemic strokeRankin ScaleSuccessful thrombectomyPostreperfusion period
2019
Diffusion tensor tractography in children with sensory processing disorder: Potentials for devising machine learning classifiers
Payabvash S, Palacios EM, Owen JP, Wang MB, Tavassoli T, Gerdes M, Brandes-Aitken A, Marco EJ, Mukherjee P. Diffusion tensor tractography in children with sensory processing disorder: Potentials for devising machine learning classifiers. NeuroImage Clinical 2019, 23: 101831. PMID: 31035231, PMCID: PMC6488562, DOI: 10.1016/j.nicl.2019.101831.Peer-Reviewed Original ResearchConceptsPosterior white matter tractsSupport vector machineAccurate classification rateNaïve BayesDifferent machineNeural networkVector machineRandom forestClassification rateRandom forest modelMachineEdge densityConnectivity metricsAlgorithmDTI/High accuracyForest modelMetricsAccuracyBrain's inabilityBayesClassifierNetworkSensory processing disordersClassification
2017
Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis
Payabvash S, Taleb S, Qureshi AI. Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis. British Journal Of Radiology 2017, 90: 20160869. PMID: 28165757, PMCID: PMC5605076, DOI: 10.1259/bjr.20160869.Peer-Reviewed Original ResearchConceptsM1 segment occlusionDisability/deathSuccessful endovascular recanalizationVoxel-based analysisFinal infarct volumeSuccessful recanalizationSegment occlusionInfarct volumeFavorable outcomePrecentral gyrusCerebral regionsEndovascular recanalizationEndovascular treatmentInsular ribbonSmaller final infarct volumesDays post-symptom onsetMiddle cerebral artery M1 segmentModified Rankin Scale scoreCerebral Infarction scoreTimely reperfusion treatmentEarly clinical outcomesHigh ratePost-symptom onsetSmaller infarct volumesRankin Scale score
2016
Prominent cortical and medullary veins on susceptibility-weighted images of acute ischaemic stroke
Payabvash S, Benson JC, Taleb S, Rykken JB, Hoffman B, Oswood MC, McKinney AM. Prominent cortical and medullary veins on susceptibility-weighted images of acute ischaemic stroke. British Journal Of Radiology 2016, 89: 20160714. PMID: 27805839, PMCID: PMC5604931, DOI: 10.1259/bjr.20160714.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeLarger infarct volumesMedullary veinsIschemic strokeInfarct volumeArterial occlusionSusceptibility-weighted imagesConsecutive patientsClinical outcomesCortical veinsProminent cortical veinsPosterior circulation territoryPoor clinical outcomeSeverity of symptomsFair interobserver agreementSWI seriesAcute strokeSymptom onsetIndependent predictorsClinical variablesSWI scansPatientsStrokeImaging implicationsProminent veins
2013
Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients
Qian J, Payabvash S, Kemmling A, Lev MH, Schwamm LH, Betensky RA. Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients. Biometrics 2013, 70: 153-163. PMID: 24320930, PMCID: PMC3954429, DOI: 10.1111/biom.12113.Peer-Reviewed Original ResearchConceptsMassachusetts General HospitalCase-control studyStroke patientsAcute ischemic stroke patientsBrain regionsMatched Case-Control StudyHospital-Acquired PneumoniaIschemic stroke patientsLarge prospective studiesUnconditional logistic regressionCase-control designSpecific brain regionsAcquired PneumoniaAcute infarctionClinical featuresProspective studyClinical variablesGeneral HospitalEpidemiologic studiesPatientsModern imagingLarger studyLogistic regressionAppropriate statistical analysisHAP studiesGood Outcome Rate of 35% in IV-tPA–Treated Patients With Computed Tomography Angiography Confirmed Severe Anterior Circulation Occlusive Stroke
González RG, Furie KL, Goldmacher GV, Smith WS, Kamalian S, Payabvash S, Harris GJ, Halpern EF, Koroshetz WJ, Camargo EC, Dillon WP, Lev MH. Good Outcome Rate of 35% in IV-tPA–Treated Patients With Computed Tomography Angiography Confirmed Severe Anterior Circulation Occlusive Stroke. Stroke 2013, 44: 3109-3113. PMID: 24003051, PMCID: PMC4374554, DOI: 10.1161/strokeaha.113.001938.Peer-Reviewed Original ResearchConceptsAnterior circulation occlusionGood outcome rateIV-tPACT angiographyBetter outcomesRankin ScaleOutcome ratesAnterior circulation ischemic strokeHealth Stroke Scale scoreIntravenous tissue plasminogen activatorAdmission National InstitutesEndovascular therapy trialsNoncontrast CT scanningStroke Scale scoreLarge artery occlusionIV-tPA treatmentLogistic regression analysisTissue plasminogen activatorRoutine clinical protocolsSymptomatic strokeOcclusive strokeAcute strokeAdmission NIHSSArtery occlusionIschemic stroke
2012
Location-weighted CTP analysis predicts early motor improvement in stroke
Payabvash S, Souza LC, Kamalian S, Wang Y, Passanese J, Kamalian S, Fung SH, Halpern EF, Schaefer PW, Gonzalez RG, Furie KL, Lev MH. Location-weighted CTP analysis predicts early motor improvement in stroke. Neurology 2012, 78: 1853-1859. PMID: 22573641, PMCID: PMC3369521, DOI: 10.1212/wnl.0b013e318258f799.Peer-Reviewed Original ResearchConceptsAcute stroke patientsAdmission NIHSSMotor improvementStroke patientsCT perfusionPredictive valueOnly independent clinical predictorMultivariate binary logistic regressionFrontal lobe white matterMultivariate modelIndependent clinical predictorsMotor functional improvementMotor function improvementNegative predictive valuePositive predictive valueSuperior temporal gyrusBinary logistic regressionExtremity paresisAcute strokeSymptom onsetClinical predictorsConsecutive patientsIndependent predictorsClinical outcomesImaging predictors
2006
Endoscopic Treatment of Vesicovasal and Vesicoureteral Reflux in Infants With Persisting Mesonephric Duct
Kajbafzadeh AM, Payabvash S. Endoscopic Treatment of Vesicovasal and Vesicoureteral Reflux in Infants With Persisting Mesonephric Duct. Journal Of Urology 2006, 176: 2657-2662. PMID: 17085187, DOI: 10.1016/j.juro.2006.08.027.Peer-Reviewed Original ResearchConceptsMesonephric ductEndoscopic treatmentVesicoureteral refluxAnorectal malformationsProximal prostatic urethraFirst-line therapyIpsilateral renal agenesisHigh anorectal malformationInvasive endoscopic approachInitial colostomyRecurrent sepsisMean followupProphylactic antibioticsInfants 2Line therapyUrological evaluationBladder neckGeneral anesthesiaSurgical interventionFurther episodesMale infantPoor feedingRenal agenesisAnorectal anomaliesBlood culturesIntravesical injection of botulinum toxin type A: Management of neuropathic bladder and bowel dysfunction in children with myelomeningocele
Kajbafzadeh AM, Moosavi S, Tajik P, Arshadi H, Payabvash S, Salmasi AH, Akbari HR, Nejat F. Intravesical injection of botulinum toxin type A: Management of neuropathic bladder and bowel dysfunction in children with myelomeningocele. Urology 2006, 68: 1091-1096. PMID: 17113899, DOI: 10.1016/j.urology.2006.05.056.Peer-Reviewed Original ResearchConceptsMaximal detrusor pressureClean intermittent catheterizationMaximal bladder capacityBowel dysfunctionBotulinum toxin ANeuropathic bladderIntermittent catheterizationBladder capacityDetrusor pressureToxin AMean maximal detrusor pressureBotulinum toxin type AVesicoureteral reflux gradeConventional urodynamic studiesToxin type ATreatment of childrenIncontinence gradeDetrusor hyperreflexiaUrine incontinenceIntravesical injectionReflux gradeUrodynamic studiesDetrusor muscleVesicoureteral refluxCystoscopic guidance