2022
Chemical complementarity between tumor resident, T-cell receptor CDR3s and MAGEA3/6 correlates with increased melanoma survival: Potential relevance to MAGE vaccine auto-reactivity
Eakins R, Chobrutskiy A, Teer J, Patel D, Hsiang M, Huda T, Zaman S, Sexton W, Coppola D, Falasiri S, Blanck G, Chobrutskiy B. Chemical complementarity between tumor resident, T-cell receptor CDR3s and MAGEA3/6 correlates with increased melanoma survival: Potential relevance to MAGE vaccine auto-reactivity. Molecular Immunology 2022, 150: 58-66. PMID: 35987136, DOI: 10.1016/j.molimm.2022.08.001.Peer-Reviewed Original Research
2018
MMP7 sensitivity of mutant ECM proteins: An indicator of melanoma survival rates and T-cell infiltration
Zaman S, Chobrutskiy BI, Patel JS, Callahan BM, Tong WL, Mihyu MM, Blanck G. MMP7 sensitivity of mutant ECM proteins: An indicator of melanoma survival rates and T-cell infiltration. Clinical Biochemistry 2018, 63: 85-91. PMID: 30414845, DOI: 10.1016/j.clinbiochem.2018.11.004.Peer-Reviewed Original ResearchConceptsMutant amino acidsT-cell infiltratesT cell infiltrationMelanoma survival ratesDistinct survival outcomesCancer Genome AtlasSurvival outcomesWorse outcomesImmune activitySurvival rateMelanoma specimensMelanomaGenome AtlasPatientsAmino acidsOverall mutationsDetection of melanomaOutcomesOnly decrease