2009
Skin immune surveillance by T cells—A new order?
Strid J, Tigelaar RE, Hayday AC. Skin immune surveillance by T cells—A new order? Seminars In Immunology 2009, 21: 110-120. PMID: 19369094, DOI: 10.1016/j.smim.2009.03.002.Peer-Reviewed Original ResearchConceptsImmune surveillanceAdaptive immune surveillanceStress-induced antigensSystemic immune cellsSkin immune surveillanceLocal lymphocytesOrgan dysfunctionDendritic cellsImmune cellsT cellsEpithelial cellsTissue integrityCellsSurveillanceBody surfaceImmunopathologyImmunoregulationDysfunctionLymphocytesInfectionAntigenImmunoprotectionStress response
1990
Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity.
Cruz P, Tigelaar R, Bergstresser P. Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity. The Journal Of Immunology 1990, 144: 2486-92. PMID: 1969448, DOI: 10.4049/jimmunol.144.7.2486.Peer-Reviewed Original ResearchConceptsLow-dose UVB radiationContact hypersensitivityLangerhans cellsIntravenous infusionLow-dose ultraviolet B (UVB) radiationExposure of LCThy-1UVB radiationSuppressor signalsMesenteric lymph nodesLow-dose UVBEffector signalsSkin graft experimentsLC migrationImmunologic targetsLymph nodesAllogeneic transferCH responsesLymphoid tissueImmune responseSyngeneic miceImmunization modelImmunogenic propertiesInfusionUltraviolet B radiation
1985
Lymphocyte Traffic and the Skin
Tigelaar R. Lymphocyte Traffic and the Skin. Dermatologic Clinics 1985, 3: 569-585. PMID: 3916171, DOI: 10.1016/s0733-8635(18)30857-x.Peer-Reviewed Original ResearchConceptsPeripheral lymph nodesLymph nodesLymphocyte migrationEndothelial cellsLymphoid organsImmunologic influenceMesenteric lymph nodesMovement of lymphocytesLymphocyte membrane receptorsDifferent organ sitesSpecialized endothelial cellsNonlymphoid organsLymphocyte trafficImmunologic defenseT cellsGastrointestinal tractOrgan sitesBlast transformationMajor subsetSkinLymphocytesCommon determinantsOrgansMembrane receptorsCells
1984
Thy-1 Antigen-Bearing Dendritic Cells in Murine Epidermis Are Derived from Bone Marrow Precursors
Bergstresser P, Tigelaar R, Streilein J. Thy-1 Antigen-Bearing Dendritic Cells in Murine Epidermis Are Derived from Bone Marrow Precursors. Journal Of Investigative Dermatology 1984, 83: 83-87. PMID: 6147381, DOI: 10.1111/1523-1747.ep12262587.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntigens, SurfaceBone MarrowBone Marrow CellsBone Marrow TransplantationCell MovementEpidermal CellsEpidermisFluorescent Antibody TechniqueHematopoietic Stem CellsIsoantibodiesLangerhans CellsMiceMice, Inbred AKRMice, Inbred DBARadiation ChimeraSkin TransplantationThy-1 AntigensConceptsLangerhans cellsBone marrow precursorsThy-1 antigenMurine epidermisThy-1Thy-1.2Anti-I-Ad antibodiesMarrow precursorsRecipient-derived cellsBone marrow chimerasDendritic Langerhans cellsNormal skin epidermisNormal murine epidermisAKR recipientsGraft epidermisDendritic cellsHematogenous cellsDonor originSystemic availabilityAKR miceSame graftLethal irradiationLymphoid cellsAbdominal skinGraft