2024
Comparative analysis of energy expenditure and costs in neuroimaging
Signorile W, Mahajan A, Fulbright R, Zubair A. Comparative analysis of energy expenditure and costs in neuroimaging. Journal Of The Neurological Sciences 2024, 460: 123001. PMID: 38616465, DOI: 10.1016/j.jns.2024.123001.Peer-Reviewed Original Research
2023
Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas.
Tabor J, O'Brien J, Vasandani S, Vetsa S, Lei H, Jalal M, Marianayagam N, Jin L, Millares Chavez M, Haynes J, Dincer A, Yalcin K, Aguilera S, Omay S, Mishra-Gorur K, McGuone D, Morales-Valero S, Fulbright R, Gunel M, Erson-Omay E, Moliterno J. Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas. Journal Of Neurosurgery 2023, 139: 1648-1656. PMID: 37243548, DOI: 10.3171/2023.4.jns222929.Peer-Reviewed Original ResearchConceptsSubtotal resectionSupratentorial tumorsElevated Ki-67High-risk featuresProgression-free survivalChromosome 1p deletionInfratentorial counterpartsInfratentorial tumorsPostoperative managementSomatic driver mutationsCerebral convexityGrade IIInfratentorial meningiomasKi-67Posterior fossaLoss of heterozygosityMeningiomasResectionTumorsWhole-exome sequencing dataDriver mutationsHigh gradeSignificant differencesExome sequencing dataSporadic meningiomasSurgical strategies for intracranial meningioma in the molecular era
Dincer A, Morales-Valero S, Robert S, Tabor J, O’Brien J, Yalcin K, Fulbright R, Erson-Omay Z, Dunn I, Moliterno J. Surgical strategies for intracranial meningioma in the molecular era. Journal Of Neuro-Oncology 2023, 162: 253-265. PMID: 37010677, PMCID: PMC10167142, DOI: 10.1007/s11060-023-04272-z.Peer-Reviewed Original ResearchConceptsExtent of resectionGrade 1 tumorsInfluence of surgeryTreatment of choiceHigh recurrence rateBiology of meningiomasIntroductionSurgical resectionSymptomatic recurrenceDisease recurrenceDefinitive managementRecurrence rateSurgical strategyWHO gradeIntracranial meningiomasClinical predictive powerMalignant transformationGrading scaleNatural historyMeningiomasUnexpected recurrenceRecurrence
2020
Primary melanotic tumors of the nervous system: a consecutive case series
Grosshans H, Huttner A, Piepmeier J, Kaulen L, Fulbright R, Baehring J, Karschnia P. Primary melanotic tumors of the nervous system: a consecutive case series. European Journal Of Neurology 2020, 27: 2303-2307. PMID: 32654331, DOI: 10.1111/ene.14437.Peer-Reviewed Original ResearchConceptsPrimary melanotic tumorsNervous systemRelapsed diseaseClinical presentationMelanotic lesionsFavorable outcomeRadiation therapyPre-contrast T1-weighted imagingRelative incidenceMelanotic tumorsHomogenous contrast enhancementYale Cancer CenterAggressive surgical treatmentConsecutive case seriesPsammomatous melanotic schwannomaNervous system tumorsT1-weighted imagingT2-weighted imagingTumor mass effectMagnetic resonance imagingMelanin-containing cellsS100 positivitySurgical resectionSurgical treatmentTumor Registry
2005
Intravascular lymphoma: magnetic resonance imaging correlates of disease dynamics within the central nervous system
Baehring J, Henchcliffe C, Ledezma C, Fulbright R, Hochberg F. Intravascular lymphoma: magnetic resonance imaging correlates of disease dynamics within the central nervous system. Journal Of Neurology Neurosurgery & Psychiatry 2005, 76: 540. PMID: 15774442, PMCID: PMC1739607, DOI: 10.1136/jnnp.2003.033662.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntigens, CDBiopsyBrainBrain NeoplasmsCervical VertebraeCognition DisordersDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingDisease ProgressionFemaleFunctional LateralityHumansLymphoma, Non-HodgkinMagnetic Resonance ImagingMaleMiddle AgedParaparesisPsychotic DisordersRetrospective StudiesThoracic VertebraeVascular NeoplasmsConceptsIntravascular lymphomaCentral nervous systemNervous systemMagnetic resonance imaging correlatesAbnormal FLAIR signalTime pointsNew clinical markerMagnetic resonance imaging protocolSmall vessel strokeInitial contrast enhancementMajority of casesExtraneural manifestationsInversion recovery sequenceRelative predilectionInitial presentationSubacute stageChronic stageFLAIR signalRetrospective seriesSystemic findingsHyperintense lesionsHodgkin's lymphomaSingle institutionFLAIR abnormalitiesHyperintense areas
2001
Functional MR imaging of regional brain activation associated with the affective experience of pain.
Fulbright R, Troche C, Skudlarski P, Gore J, Wexler B. Functional MR imaging of regional brain activation associated with the affective experience of pain. American Journal Of Roentgenology 2001, 177: 1205-10. PMID: 11641204, DOI: 10.2214/ajr.177.5.1771205.Peer-Reviewed Original ResearchConceptsAnterior cingulate gyrusSuperior frontal gyrusCingulate gyrusPain taskRight cuneusFunctional MRFrontal gyrusRight superior frontal gyrusBrain activationPain-related activationCold pressor testLeft anterior insulaExperience of painRegional brain activationFunctional MR imagingMotor-sensory areasPainful temperaturesPain thresholdLeft thalamusPressor testPainful levelsPostcentral gyrusPainFrontal lobeHealthy adultsThe Functional Neural Architecture of Components of Attention in Language-Processing Tasks
Shaywitz B, Shaywitz S, Pugh K, Fulbright R, Skudlarski P, Mencl W, Constable R, Marchione K, Fletcher J, Klorman R, Lacadie C, Gore J. The Functional Neural Architecture of Components of Attention in Language-Processing Tasks. NeuroImage 2001, 13: 601-612. PMID: 11305889, DOI: 10.1006/nimg.2000.0726.Peer-Reviewed Original ResearchConceptsInferior frontal sitesFrontal sitesAttentional controlExecutive functionFunctional neural architectureFunctional magnetic resonanceLanguage processing tasksLeft hemisphere sitesSelective attentionPerceptual selectivityRight-handed manParietal sitesRight hemisphereCortical systemsLanguage processingNeural architectureFrontal cortexIncreased activationHemisphere sitesWordsTaskImportant dimensionSpecific functional aspectsAttentionProcessing
2000
Contribution of the Anteromedial Temporal Lobes to the Evaluation of Facial Emotion
Anderson A, Spencer D, Fulbright R, Phelps E. Contribution of the Anteromedial Temporal Lobes to the Evaluation of Facial Emotion. Neuropsychology 2000, 14: 526-536. PMID: 11055255, DOI: 10.1037/0894-4105.14.4.526.Peer-Reviewed Original ResearchConceptsAnteromedial temporal lobeSubcortical limbic regionsAnteromedial temporal lobectomyTemporal lobectomyCortical lesionsLimbic regionsLTL patientsAdjacent cortexCortical functionTemporal lobeNormal controlsRight amygdalaCortical contributionNeural circuitsPatientsSevere deficitsAmygdala damageIntensity ratingsHemispheric specializationGlobal deficitDeficitsExpressionLobectomyLesionsAmygdalaNetwork analysis of brain activations in working memory: Behavior and age relationships
Mencl W, Pugh K, Shaywitz S, Shaywitz B, Fulbright R, Constable R, Skudlarski P, Katz L, Marchione K, Lacadie C, Gore J. Network analysis of brain activations in working memory: Behavior and age relationships. Microscopy Research And Technique 2000, 51: 64-74. PMID: 11002354, DOI: 10.1002/1097-0029(20001001)51:1<64::aid-jemt7>3.0.co;2-d.Peer-Reviewed Original ResearchConceptsMedial temporal lobeFunctional magnetic resonance imagingBrain activationTemporal lobeBetter memory performanceInferior frontal gyrusRight medial temporal lobeRight prefrontal regionsMedial frontal cortexInferior temporal lobeMemory recognitionMemory testMemory performanceInferior frontalPrefrontal regionsFrontal gyrusNew stimuliExtrastriate cortexRehearsal periodMemory impairmentBrain scoreOlder subjectsVisual formAge effectsRecognition periodThe Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex
Pugh K, Mencl W, Shaywitz B, Shaywitz S, Fulbright R, Constable R, Skudlarski P, Marchione K, Jenner A, Fletcher J, Liberman A, Shankweiler D, Katz L, Lacadie C, Gore J. The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex. Psychological Science 2000, 11: 51-56. PMID: 11228843, DOI: 10.1111/1467-9280.00214.Peer-Reviewed Original ResearchConceptsDevelopmental dyslexiaAngular gyrusFunctional connectivityPhonological assemblyLeft hemispherePhonological processing domainTask-specific differencesLanguage-dominant left hemispherePosterior brain regionsTemporal lobe sitesDyslexic readersNeurobiological anomaliesPhonological performanceExplicit demandDyslexiaBrain regionsGyrusPosterior cortexTaskCompensatory roleVaried demandsPosterior regionDyslexicsConnectivityHemisphere
1999
Predicting Midsagittal Pharynx Shape From Tongue Position During Vowel Production
Whalen DH, Kang A, Magen H, Fulbright R, Gore J. Predicting Midsagittal Pharynx Shape From Tongue Position During Vowel Production. Journal Of Speech Language And Hearing Research 1999, 42: 592-603. PMID: 10391625, DOI: 10.1044/jslhr.4203.592.Peer-Reviewed Original Research
1998
Functional MRI studies of auditory comprehension
Schlosser M, Aoyagi N, Fulbright R, Gore J, McCarthy G. Functional MRI studies of auditory comprehension. Human Brain Mapping 1998, 6: 1-13. PMID: 9673659, PMCID: PMC6873385, DOI: 10.1002/(sici)1097-0193(1998)6:1<1::aid-hbm1>3.0.co;2-7.Peer-Reviewed Original ResearchConceptsEnglish sentencesAuditory comprehensionLeft superior temporal sulcusLeft inferior frontal gyrusAuditory language comprehensionPosterior temporal activationSuperior temporal sulcusInferior frontal gyrusFunctional MRI studyFunctional magnetic resonance imagesExtraoperative cortical stimulationNative English languageDominant temporal lobeLanguage comprehensionTemporal sulcusFrontal gyrusFunctional neuroimagingLess activationLanguage testingEnglish languageTemporal activationTurkish sentencesActivation patternsSame speakerTemporal lobeQuantification of intravascular and extravascular contributions to BOLD effects induced by alteration in oxygenation or intravascular contrast agents
Zhong J, Kennan R, Fulbright R, Gore J. Quantification of intravascular and extravascular contributions to BOLD effects induced by alteration in oxygenation or intravascular contrast agents. Magnetic Resonance In Medicine 1998, 40: 526-536. PMID: 9771569, DOI: 10.1002/mrm.1910400405.Peer-Reviewed Original ResearchFunctional disruption in the organization of the brain for reading in dyslexia
Shaywitz S, Shaywitz B, Pugh K, Fulbright R, Constable R, Mencl W, Shankweiler D, Liberman A, Skudlarski P, Fletcher J, Katz L, Marchione K, Lacadie C, Gatenby C, Gore J. Functional disruption in the organization of the brain for reading in dyslexia. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 2636-2641. PMID: 9482939, PMCID: PMC19444, DOI: 10.1073/pnas.95.5.2636.Peer-Reviewed Original ResearchConceptsBrain activation patternsActivation patternsDyslexic readersFunctional disruptionFunctional magnetic resonanceAlphabetic charactersRelative underactivationPhonologic awarenessNeural signaturesPhonologic analysisSpoken wordsAnterior regionImpairmentNeural systemsPosterior regionDyslexiaMagnetic resonanceWordsOveractivationBrain
1997
Cerebral vascular malformations adjacent to sensorimotor and visual cortex. Functional magnetic resonance imaging studies before and after therapeutic intervention.
Schlosser M, McCarthy G, Fulbright R, Gore J, Awad I. Cerebral vascular malformations adjacent to sensorimotor and visual cortex. Functional magnetic resonance imaging studies before and after therapeutic intervention. Stroke 1997, 28: 1130-7. PMID: 9183338, DOI: 10.1161/01.str.28.6.1130.Peer-Reviewed Original ResearchConceptsCerebral vascular malformationsVascular malformationsNeurological deficitsFunctional magnetic resonance imagingVisual cortexPrimary somatosensoryFunctional activationTherapeutic interventionsFMRI studyGross neurological deficitsConsequence of therapyMass effectMagnetic resonance imagingFunctional magnetic resonanceClinical recoveryUnaffected hemisphereVascular lesionsAnatomic displacementAnatomic localeAnatomic locationPosttherapeutic changesClinical functionHemispheric asymmetryPatientsResonance imagingPredicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification
Pugh K, Shaywitz B, Shaywitz S, Shankweiler D, Katz L, Fletcher J, Skudlarski P, Fulbright R, Constable R, Bronen R, Lacadie C, Gore J. Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification. Journal Of Experimental Psychology Human Perception & Performance 1997, 23: 299-318. PMID: 9103996, DOI: 10.1037/0096-1523.23.2.299.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingPhonological effectsLexical decision taskLexical decision latenciesLexical-semantic processesBrain activation patternsWord identificationWord recognitionDecision taskDecision latenciesRegularity effectIndividual differencesFMRI measuresHemispheric lateralizationCerebral basisExperimental paradigmActivation patternsCortical regionsLength effectYoung adultsTaskParticipantsReadingMeasuresMagnetic resonance imagingEconomic impact of replacing CT with MR imaging for refractory epilepsy
Bronen R, Fulbright R, Spencer S, Spencer D, Kim J, Lange R. Economic impact of replacing CT with MR imaging for refractory epilepsy. Magnetic Resonance Imaging 1997, 15: 857-862. PMID: 9309616, DOI: 10.1016/s0730-725x(97)00047-7.Peer-Reviewed Original ResearchConceptsPreoperative evaluationRefractory epilepsyPositive imaging findingsRefractory epilepsy patientsPositive magnetic resonanceMagnetic resonanceIntracranial electroencephalogram monitoringSurgical ameliorationNormal CTImaging findingsPreoperative localizationIntractable epilepsyVascular lesionsEpileptogenic zoneElectroencephalogram monitoringPreoperative CTEpilepsy patientsPatientsMR imagingEpilepsyCTVascular substratesHealth costsLesionsSurgeryFunctional Magnetic Resonance Imaging Assessment of the Human Brain Auditory Cortex Response to Increasing Word Presentation Rates
Dhankhar A, Wexler B, Fulbright R, Halwes T, Blamire A, Shulman R. Functional Magnetic Resonance Imaging Assessment of the Human Brain Auditory Cortex Response to Increasing Word Presentation Rates. Journal Of Neurophysiology 1997, 77: 476-483. PMID: 9120588, DOI: 10.1152/jn.1997.77.1.476.Peer-Reviewed Original ResearchConceptsSecondary auditory cortexAuditory cortex responsesTransverse temporal gyrusFunctional magnetic resonance imagingAuditory cortexSuperior temporal gyrusCortex responsesFunctional magnetic resonance imaging (fMRI) assessmentsMagnetic Resonance Imaging AssessmentTemporal gyrusPosterior-superior aspectEcho-planar functional magnetic resonance imagingMagnetic resonance imagingImaging assessmentGray matterResonance imagingSuperior aspectCortexSignificant differencesTemporal sulcusSubsequent fallGyrusT2 weightingImaging sequenceSubjectsAn fMRI study of the human cortical motor system response to increasing functional demands
Wexler B, Fulbright R, Lacadie C, Skudlarski P, Kelz M, Constable R, Gore J. An fMRI study of the human cortical motor system response to increasing functional demands. Magnetic Resonance Imaging 1997, 15: 385-396. PMID: 9223039, DOI: 10.1016/s0730-725x(96)00232-9.Peer-Reviewed Original ResearchConceptsMotor-sensory areasSupplementary motor areaFunctional magnetic resonance imagingPremotor areasMotor areaMultiple motor areasComplexity of movementCortical motor systemRight-hand finger movementsIndex finger movementsFinger movementsMagnetic resonance imagingInferior parietal areasConsistent lateralizationResonance imagingBrain regionsActivation changesMotor system responsesParietal areasHand finger movementsPreliminary reproducibility studyFMRI studySignificant main effectWeek periodGreater increase
1996
Auditory Selective Attention: An fMRI Investigation
Pugh K, Shaywitz B, Shaywitz S, Fulbright R, Byrd D, Skudlarski P, Shankweiler D, Katz L, Constable R, Fletcher J, Lacadie C, Marchione K, Gore J. Auditory Selective Attention: An fMRI Investigation. NeuroImage 1996, 4: 159-173. PMID: 9345506, DOI: 10.1006/nimg.1996.0067.Peer-Reviewed Original ResearchConceptsAttention systemAnterior attention systemPosterior attention systemAuditory selective attentionInferior frontal regionsInferior frontal gyrusMiddle temporal gyrusDichotic listening conditionsSelective attentionFMRI investigationSpeech tokensPitch judgmentsFrontal gyrusListening conditionsBroca's areaTemporal gyrusNonspeech tasksHemispheric differencesFrontal regionsTone stimuliDichotic conditionsCingulate gyrusGyrusPresent experimentsTask