2015
Three-Dimensional Morphology by Multiphoton Microscopy with Clearing in a Model of Cisplatin-Induced CKD
Torres R, Velazquez H, Chang JJ, Levene MJ, Moeckel G, Desir GV, Safirstein R. Three-Dimensional Morphology by Multiphoton Microscopy with Clearing in a Model of Cisplatin-Induced CKD. Journal Of The American Society Of Nephrology 2015, 27: 1102-1112. PMID: 26303068, PMCID: PMC4814184, DOI: 10.1681/asn.2015010079.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCisplatinDisease Models, AnimalImaging, Three-DimensionalMiceMicroscopy, Fluorescence, MultiphotonRenal Insufficiency, ChronicConceptsAtubular glomeruliGlomerular capsuleRole of fibrosisModel of cisplatinNew mouse modelUseful morphologic informationMultiphoton microscopyTraditional histologic methodsRenal diseaseCisplatin therapyGlomerular volumePathologic changesRenal sectionsCKDMouse modelCisplatin effectCisplatin exposureImportant causeMild increaseCuboidal cellsHistologic methodsMorphologic informationFibrosisTherapyGlomeruli
2013
High-Resolution, 2- and 3-Dimensional Imaging of Uncut, Unembedded Tissue Biopsy Samples
Torres R, Vesuna S, Levene MJ. High-Resolution, 2- and 3-Dimensional Imaging of Uncut, Unembedded Tissue Biopsy Samples. Archives Of Pathology & Laboratory Medicine 2013, 138: 395-402. PMID: 23829375, DOI: 10.5858/arpa.2013-0094-oa.Peer-Reviewed Original ResearchConceptsImmediate therapeutic decisionsPractical clinical toolComprehensive visual examinationTissue biopsy samplesBiopsy specimensKidney specimensAncillary studiesGold standard techniqueTherapeutic decisionsRenal tissueBiopsy samplesHematoxylin-eosinHuman prostateMorphologic effectsNormal reactivityClinical settingClinical toolMultiphoton microscopyPathology samplesHistologic techniquesPreservation of tissuesExcellent morphologic detailTraditional histologyFurther investigationTissue
2011
Multiphoton fluorescence, second harmonic generation, and fluorescence lifetime imaging of whole cleared mouse organs
Vesuna S, Torres R, Levene MJ. Multiphoton fluorescence, second harmonic generation, and fluorescence lifetime imaging of whole cleared mouse organs. Journal Of Biomedical Optics 2011, 16: 106009-106009-6. PMID: 22029356, DOI: 10.1117/1.3641992.Peer-Reviewed Original ResearchMeSH KeywordsAnimal StructuresAnimalsImaging, Three-DimensionalJointsMaleMiceMice, Inbred C57BLMicroscopy, Fluorescence, MultiphotonOptical PhenomenaTestis