2022
Animal models of the immunology and pathogenesis of human babesiosis
Kumar A, Kabra A, Igarashi I, Krause P. Animal models of the immunology and pathogenesis of human babesiosis. Trends In Parasitology 2022, 39: 38-52. PMID: 36470781, DOI: 10.1016/j.pt.2022.11.003.Peer-Reviewed Original ResearchConceptsAnimal modelsHuman babesiosisBabesia infectionImmunological mechanismsModerate diseaseOrgan dysfunctionPathologic responseDisease complicationsAsymptomatic infectionSevere diseaseAnimal studiesInfectionPathological processesDiseaseBabesiosisBabesia speciesAnimalsDomestic animalsComplicationsDysfunctionPathogenesisImmunology
2015
Human babesiosis
Chen T, Mamoun C, Krause P. Human babesiosis. 2015, 1295-1301. DOI: 10.1017/cbo9781139855952.226.Peer-Reviewed Original ResearchHuman babesiosisB. microtiB. microti infectionHard-bodied ticksClustering of casesHuman granulocytic anaplasmosisAcute illnessRenal failureBlood transfusionMicroti infectionCommon causeBabesia duncaniEndemic areasEtiologic agentHuman infectionsHuman B. microti infectionIntraerythrocytic protozoaLyme diseaseBabesia microtiBabesia speciesDiseaseGranulocytic anaplasmosisBabesia infectionIntraerythrocytic parasitesInfection
2008
Human Babesiosis
Chen T, Krause P. Human Babesiosis. 2008, 1381-1388. DOI: 10.1017/cbo9780511722240.200.Peer-Reviewed Original ResearchHuman babesiosisB. microtiBabesia speciesB. microti infectionHard-bodied ticksClustering of casesHuman granulocytic anaplasmosisEastern North AmericaAcute illnessBlood transfusionRenal failureMicroti infectionCommon causeBabesia duncaniEndemic areasEtiologic agentHuman B. microti infectionBabesial infectionIntraerythrocytic protozoaBabesia microtiLyme diseaseDiseaseGranulocytic anaplasmosisIntraerythrocytic parasitesNorth America
2000
Babesiosis
Homer M, Aguilar-Delfin I, Telford S, Krause P, Persing D. Babesiosis. Clinical Microbiology Reviews 2000, 13: 451-469. PMID: 10885987, PMCID: PMC88943, DOI: 10.1128/cmr.13.3.451-469.2000.Peer-Reviewed Original ResearchConceptsSpecies of BabesiaMalaria-like diseaseWidespread blood parasitesPear-shaped formsPossible pathogenic mechanismsAppropriate patient managementInfected red blood cellsHematotropic parasitesVeterinary impactBabesia speciesGenus BabesiaIxodid ticksBabesial parasitesZoonotic diseaseRed blood cellsBabesia divergensSilent infectionAnimal hostsEpidemiological descriptionDisease manifestationsPatient managementImmunological responseSevere hemolysisB. microtiTransmission cycleBabesiosis
Homer M, Aguilar-Delfin I, Telford S, Krause P, Persing D. Babesiosis. Clinical Microbiology Reviews 2000, 13: 451-469. DOI: 10.1128/cmr.13.3.451.Peer-Reviewed Original ResearchPossible pathogenic mechanismsAppropriate patient managementInfected red blood cellsSpecies of BabesiaMalaria-like diseaseWidespread blood parasitesRed blood cellsSilent infectionEpidemiological descriptionDisease manifestationsPatient managementImmunological responsePear-shaped formsSevere hemolysisDisease processPathogenic mechanismsHematotropic parasitesBabesia microtiBabesial parasitesDiagnostic testsBlood cellsVeterinary impactBabesia speciesGenus BabesiaIxodid ticks