Astrocytes and Epilepsy
de Lanerolle NC, Lee TS, Spencer DD. Astrocytes and Epilepsy. Neurotherapeutics 2010, 7: 424-438. PMID: 20880506, PMCID: PMC5084304, DOI: 10.1016/j.nurt.2010.08.002.Peer-Reviewed Original ResearchConceptsSeizure focusReactive astrocytesCausation of seizuresGlial fibrillary acidic proteinHippocampal seizure focusRole of astrocytesTemporal lobe epilepsyFibrillary acidic proteinPositive reactive astrocytesNonsclerotic hippocampiHippocampal sclerosisSclerotic hippocampusSubicular neuronsLobe epilepsyEpileptiform activityInflammatory functionsAstrocytesAction potentialsAcidic proteinPotassium ion channelsVascular interfaceEpilepsyHippocampusPrecise roleHuman brain