2023
Passive transfer of alloantibodies through breast milk as a mediator of hemolytic anemia
Abels E, Jacobs J, Prior D, Willets L, Sostin N, Tormey C, Binns T. Passive transfer of alloantibodies through breast milk as a mediator of hemolytic anemia. Transfusion 2023, 63: 2188-2196. PMID: 37706556, DOI: 10.1111/trf.17548.Peer-Reviewed Original ResearchConceptsMaternal breast milkBreast milkNeonatal circulationRed blood cellsPassive transferAntiviral IgG antibodiesResolution of anemiaPaucity of dataNeonatal red blood cellsIntravenous immunoglobulinMaternal alloantibodiesMaternal antibodiesPlacental transferRBC antibodiesIgG antibodiesHemolytic diseaseHemolytic anemiaPlasma titersAlloantibodiesHDFNBlood cellsAntibodiesSignificant decreasePatientsAnemiaWarm autoantibodies mimicking alloantibodies: Three cases of autoantibodies with unusual antigenic specificity
Jacobs J, Binns T, Abels E, Campos J, Elkabbani R, Kress A, Sostin N, Tormey C. Warm autoantibodies mimicking alloantibodies: Three cases of autoantibodies with unusual antigenic specificity. American Journal Of Clinical Pathology 2023, 160: 561-565. PMID: 37598315, DOI: 10.1093/ajcp/aqad095.Peer-Reviewed Original ResearchConceptsWarm autoantibodiesRed blood cellsAntigenic specificityCase of autoantibodiesCase 1Autoimmune hemolytic anemiaDirect antiglobulin testRBC transfusionPregnant womenTransfusion reactionsAntiglobulin testHemolytic anemiaAutoantibodiesRBC antigensAntibody detectionRBC unitsRare reportsBlood cellsCase 2Immunohematologic testingSignificant hemolysisRhD typingCase 3AlloantibodiesAutoantiHemolytic disease of the fetus and newborn mediated by anti-Dia in a U.S. hospital
Jacobs J, Abels E, Binns T, Tormey C, Sostin N. Hemolytic disease of the fetus and newborn mediated by anti-Dia in a U.S. hospital. Immunohematology 2023, 39: 32-34. PMID: 37017601, DOI: 10.21307/immunohematology-2023-006.Peer-Reviewed Case Reports and Technical NotesConceptsHemolytic diseaseCases of HDFNU.S. hospitalsHemolytic transfusion reactionsDirect antiglobulin testNeonatal bilirubin levelsSouth American descentAntibody detection testsLow-prevalence antigensU.S. patient populationNear universal absenceHDFN casesBilirubin levelsPatient populationTransfusion reactionsAntiglobulin testUnexpected causeHispanic ethnicityBlood group systemAntigenAntibodiesHDFNHospitalFetusesDisease
2022
Alloimmunization following antigen‐negative red blood cell transfusion
Jacobs J, Binns T, Abels E, Iyer K, Villalba C, Verma A, Sostin N, Tormey C. Alloimmunization following antigen‐negative red blood cell transfusion. Transfusion 2022, 63: 430-434. PMID: 36458330, DOI: 10.1111/trf.17208.Peer-Reviewed Case Reports and Technical NotesConceptsTransfusion of RBCsRed blood cell transfusionRed blood cell alloimmunizationPrevious antigen exposureBlood cell transfusionAlloantibody specificitiesCell transfusionRBC transfusionAntigen exposureRBC alloantibodiesAntigenic stimulusDetectable titersAntigenic stimulationMyeloid neoplasmsTransfusionAlloantibodiesAlloimmunizationParticular antigenPrior exposureStimulatory eventsExact mechanismCorresponding antibodiesRBCsExposurePregnancy