Na Wang
Associate Research ScientistCards
About
Research
Publications
2024
Decoding transcriptomic signatures of cysteine string protein alpha–mediated synapse maintenance
Wang N, Zhu B, Allnutt M, Grijalva R, Zhao H, Chandra S. Decoding transcriptomic signatures of cysteine string protein alpha–mediated synapse maintenance. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2320064121. PMID: 38833477, PMCID: PMC11181078, DOI: 10.1073/pnas.2320064121.Peer-Reviewed Original ResearchConceptsSynapse maintenanceTranscriptional changesSynaptogenic adhesion moleculesGene ontology analysisKO miceKO brainMaintenance in vivoCell-cell interactionsGlial cellsSingle-nucleus transcriptomesOntology analysisCspADifferential expressionNeuron-glia interactionsAutophagy-related genesProtein AGenesCell typesNeurodegenerative diseasesInhibitory synapsesLittermate controlsSynaptic pathwaysAdhesion moleculesGlial responseSynapse
2022
Potassium channel K(ir) 4.1 regulates oligodendrocyte differentiation via intracellular pH regulation.
Wang N, Zhou L, Shao CY, Wang XT, Zhang N, Ma J, Hu HL, Wang Y, Qiu M, Shen Y. Potassium channel K(ir) 4.1 regulates oligodendrocyte differentiation via intracellular pH regulation. Glia 2022, 70: 2093-2107. PMID: 35775976, DOI: 10.1002/glia.24240.Peer-Reviewed Original Research
2020
Magneto is ineffective in controlling electrical properties of cerebellar Purkinje cells.
Xu FX, Zhou L, Wang XT, Jia F, Ma KY, Wang N, Lin L, Xu FQ, Shen Y. Magneto is ineffective in controlling electrical properties of cerebellar Purkinje cells. Nature Neuroscience 2020, 23: 1041-1043. PMID: 31570863, DOI: 10.1038/s41593-019-0475-3.Peer-Reviewed Original ResearchGab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination.
Zhou L, Shao CY, Xie YJ, Wang N, Xu SM, Luo BY, Wu ZY, Ke YH, Qiu M, Shen Y. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. ELife 2020, 9 PMID: 31944179, PMCID: PMC6984811, DOI: 10.7554/eLife.52056.Peer-Reviewed Original Research
2019
Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors.
Wang N, Wang DD, Shen Y. Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors. Neuroscience Letters 2019, 707: 134291. PMID: 31129078, DOI: 10.1016/j.neulet.2019.134291.Peer-Reviewed Original Research
2018
Numb-p72, but not Numb-p65, contributes to the trafficking of group I metabotropic glutamate receptors.
Wang N, Cai XY, Gao W, Shen Y. Numb-p72, but not Numb-p65, contributes to the trafficking of group I metabotropic glutamate receptors. Neuroreport 2018, 29: 902-906. PMID: 29762249, DOI: 10.1097/WNR.0000000000001051.Peer-Reviewed Original ResearchCelecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy.
Zhou L, Zhou L, Su LD, Cao SL, Xie YJ, Wang N, Shao CY, Wang YN, Zhou JH, Cowell JK, Shen Y. Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience 2018, 38: 3346-3357. PMID: 29491011, PMCID: PMC5884462, DOI: 10.1523/JNEUROSCI.3245-17.2018.Peer-Reviewed Original Research
2016
Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons.
Xu J, Wang N, Luo JH, Xia J. Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons. Scientific Reports 2016, 6: 20924. PMID: 26868290, PMCID: PMC4751430, DOI: 10.1038/srep20924.Peer-Reviewed Original Research
2015
Functions of kinesin superfamily proteins in neuroreceptor trafficking.
Wang N, Xu J. Functions of kinesin superfamily proteins in neuroreceptor trafficking. BioMed Research International 2015, 2015: 639301. PMID: 26075252, PMCID: PMC4449888, DOI: 10.1155/2015/639301.Peer-Reviewed Original Research