Featured Publications
Detection of functional connectivity using temporal correlations in MR images
Hampson M, Peterson BS, Skudlarski P, Gatenby JC, Gore JC. Detection of functional connectivity using temporal correlations in MR images. Human Brain Mapping 2002, 15: 247-262. PMID: 11835612, PMCID: PMC6872035, DOI: 10.1002/hbm.10022.Peer-Reviewed Original ResearchOrbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity
Scheinost D, Stoica T, Saksa J, Papademetris X, Constable RT, Pittenger C, Hampson M. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Translational Psychiatry 2013, 3: e250-e250. PMID: 23632454, PMCID: PMC3641411, DOI: 10.1038/tp.2013.24.Peer-Reviewed Original ResearchConceptsResting-state connectivityContamination anxietyBrain regionsNF trainingBrain connectivityResting-state functional connectivityFunctional magnetic resonance imaging (fMRI) neurofeedbackPotential of neurofeedbackRelevant brain networksResting-state fMRIDorsolateral prefrontal cortexTarget brain regionsBrain functional architectureUseful therapyLimbic circuitryMatched subjectsOrbitofrontal regionsOrbitofrontal cortexFunctional connectivityPrefrontal cortexHuman emotionsFeedback control tasksSubclinical anxietyAnxiety regulationBrain networks
2023
Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome
Awasthi J, Harris-Starling C, Kalvin C, Pittman B, Park H, Bloch M, Fernandez T, Sukhodolsky D, Hampson M. Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome. Psychiatry Research Neuroimaging 2023, 336: 111692. PMID: 37673711, PMCID: PMC10722977, DOI: 10.1016/j.pscychresns.2023.111692.Peer-Reviewed Case Reports and Technical NotesConceptsTourette syndromeFunctional magnetic resonance imagingStudy protocolChronic tic disorderSupplementary motor areaLower functional connectivityMagnetic resonance imagingResearch study protocolLarge trialsClinical trialsTic disordersMotor areaBrain areasControl groupResonance imagingBrain regionsNew trialsFunctional connectivityNeurofeedback interventionFMRI neurofeedbackNF protocolTrialsNF studiesSyndromeIntervention
2022
Systemic inflammation enhances stimulant-induced striatal dopamine elevation in tobacco smokers
Zakiniaeiz Y, Hoye J, Ryan Petrulli J, LeVasseur B, Stanley G, Gao H, Najafzadeh S, Ropchan J, Nabulsi N, Huang Y, Chen MK, Matuskey D, Barron DS, Kelmendi B, Fulbright RK, Hampson M, Cosgrove KP, Morris ED. Systemic inflammation enhances stimulant-induced striatal dopamine elevation in tobacco smokers. Brain Behavior And Immunity 2022, 106: 262-269. PMID: 36058419, PMCID: PMC10097458, DOI: 10.1016/j.bbi.2022.08.016.Peer-Reviewed Original ResearchConceptsEffects of LPSDopamine elevationTobacco smokersHealthy controlsSystemic inflammationDopamine systemImmune-brain interactionReward-related brain regionsAdministration of placeboAdministration of LPSSmoking statusRepeated-measures ANOVAPathophysiology of addictionDrug dosingPlaceboIndependent cohortSmokersDrug reinforcementEffect size determinationImmune systemRandomized orderBrain regionsLPSMethylphenidatePBO condition
2020
Connectome-based neurofeedback: A pilot study to improve sustained attention
Scheinost D, Hsu TW, Avery EW, Hampson M, Constable RT, Chun MM, Rosenberg MD. Connectome-based neurofeedback: A pilot study to improve sustained attention. NeuroImage 2020, 212: 116684. PMID: 32114151, PMCID: PMC7165055, DOI: 10.1016/j.neuroimage.2020.116684.Peer-Reviewed Original ResearchConceptsFunctional connectivityRt-fMRIReal-time functional magnetic resonance imaging (rt-fMRI) neurofeedbackWhole-brain functional connectivityClinical trial designFunctional magnetic resonance imaging (fMRI) neurofeedbackDistinct brain areasConnectome-based modelsClinical symptomsTrial designBrain areasBrain regionsSustained attentionTherapeutic toolPilot studyBrain activityFunctional connectionsSymptomsNeurofeedbackFunctional networksTraining durationAttention taskComplex functional networksPilot sample
2018
Cerebellar and Prefrontal Cortical Alterations in PTSD: Structural and Functional Evidence
Holmes SE, Scheinost D, DellaGioia N, Davis MT, Matuskey D, Pietrzak RH, Hampson M, Krystal JH, Esterlis I. Cerebellar and Prefrontal Cortical Alterations in PTSD: Structural and Functional Evidence. Chronic Stress 2018, 2: 2470547018786390. PMID: 30035247, PMCID: PMC6054445, DOI: 10.1177/2470547018786390.Peer-Reviewed Original ResearchPosttraumatic stress disorderIntrinsic connectivity distributionMedial prefrontal cortexTensor-based morphometryPTSD groupFunctional connectivityPrefrontal cortexPathophysiology of PTSDGray matter volumeWhole-brain connectivityKey brain regionsMiddle temporal gyrusDorsolateral prefrontal cortexDefault mode networkCentral executive networkFunctional connectivity analysisPFC alterationsCortical alterationsHealthy comparison participantsAltered volumeFunctional alterationsMatter volumeUnmedicated individualsCerebellar involvementBrain regions
2014
Resting state functional connectivity predicts neurofeedback response
Scheinost D, Stoica T, Wasylink S, Gruner P, Saksa J, Pittenger C, Hampson M. Resting state functional connectivity predicts neurofeedback response. Frontiers In Behavioral Neuroscience 2014, 8: 338. PMID: 25309375, PMCID: PMC4173810, DOI: 10.3389/fnbeh.2014.00338.Peer-Reviewed Original ResearchObsessive-compulsive disorderOrbitofrontal cortexFunctional connectivityNeurofeedback trainingState functional connectivityWhole-brain connectivityBrain functional connectivityResting-state fMRITarget brain regionsBrodmann area 10Clinical symptomatologyContamination anxietyProminent symptomAnterior prefrontal cortexBrain regionsNeuropsychiatric disordersRs-fMRIBehavioral improvementPrefrontal cortexSame protocolPilot dataBA 10Neurofeedback protocolReliable predictorCortex
2008
Measuring brain connectivity: Diffusion tensor imaging validates resting state temporal correlations
Skudlarski P, Jagannathan K, Calhoun VD, Hampson M, Skudlarska BA, Pearlson G. Measuring brain connectivity: Diffusion tensor imaging validates resting state temporal correlations. NeuroImage 2008, 43: 554-561. PMID: 18771736, PMCID: PMC4361080, DOI: 10.1016/j.neuroimage.2008.07.063.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingBrain connectivityWhole brain gray matterDiffusion tensorBrain gray matterDistant brain regionsDefault mode networkHealthy subjectsClinical conditionsNeuronal connectivityGray matterHealthy brainResonance imagingBrain regionsAnatomical connectivityFunctional connectivityMode networkClinical populationsSignificant correlationAnatomical regionsFunctional connectionsConnectivity mapsHuman brainBrainConnectivity matrix
2006
Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability
Hampson M, Tokoglu F, Sun Z, Schafer RJ, Skudlarski P, Gore JC, Constable RT. Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability. NeuroImage 2006, 31: 513-519. PMID: 16497520, DOI: 10.1016/j.neuroimage.2005.12.040.Peer-Reviewed Original Research
2004
Changes in functional connectivity of human MT/V5 with visual motion input
Hampson M, Olson IR, Leung HC, Skudlarski P, Gore JC. Changes in functional connectivity of human MT/V5 with visual motion input. Neuroreport 2004, 15: 1315-1319. PMID: 15167557, DOI: 10.1097/01.wnr.0000129997.95055.15.Peer-Reviewed Original Research