2022
Bayesian local exchangeability design for phase II basket trials
Liu Y, Kane M, Esserman D, Blaha O, Zelterman D, Wei W. Bayesian local exchangeability design for phase II basket trials. Statistics In Medicine 2022, 41: 4367-4384. PMID: 35777367, PMCID: PMC10279458, DOI: 10.1002/sim.9514.Peer-Reviewed Original Research
2021
Circadian Rhythm Analysis Using Wearable Device Data: Novel Penalized Machine Learning Approach
Li X, Kane M, Zhang Y, Sun W, Song Y, Dong S, Lin Q, Zhu Q, Jiang F, Zhao H. Circadian Rhythm Analysis Using Wearable Device Data: Novel Penalized Machine Learning Approach. Journal Of Medical Internet Research 2021, 23: e18403. PMID: 34647895, PMCID: PMC8554674, DOI: 10.2196/18403.Peer-Reviewed Original ResearchConceptsRhythm formationPDMS-2Motor developmentCircadian rhythm analysisPeabody Developmental Motor Scales-Second EditionFisher testChildhood motor developmentEarly childhood motor developmentWearable device dataHealthy infantsRhythm analysisClinical studiesLinear regression analysisGross motorMonthsTime pointsAge 6Bonferroni correctionEarly childhoodRhythm developmentRegression analysisOne dayAssociationDaily rhythmsActiwatch data
2020
Two‐stage randomized trial design for testing treatment, preference, and self‐selection effects for count outcomes
Shi Y, Cameron B, Gu X, Kane M, Peduzzi P, Esserman DA. Two‐stage randomized trial design for testing treatment, preference, and self‐selection effects for count outcomes. Statistics In Medicine 2020, 39: 3653-3683. PMID: 32875582, DOI: 10.1002/sim.8686.Peer-Reviewed Original ResearchConceptsTrial designPatient preferencesPatient-centered treatment strategiesTreatment effectsTraditional clinical trial designClinical trial designEnd of lifeUse of antimicrobialsTreatment strategiesHealthcare providersPatient psychologyTesting treatmentsTwo-stage designOutcomesParticular treatmentTreatmentBinary outcomesCount outcomesTrials
2019
A two‐stage phase II clinical trial design with nested criteria for early stopping and efficacy
DeVeaux M, Kane M, Wei W, Zelterman D. A two‐stage phase II clinical trial design with nested criteria for early stopping and efficacy. Pharmaceutical Statistics 2019, 18: 700-713. PMID: 31507079, PMCID: PMC6996237, DOI: 10.1002/pst.1965.Peer-Reviewed Original Research
2018
Factors Associated With Cancer Disparities Among Low-, Medium-, and High-Income US Counties
O’Connor J, Sedghi T, Dhodapkar M, Kane MJ, Gross CP. Factors Associated With Cancer Disparities Among Low-, Medium-, and High-Income US Counties. JAMA Network Open 2018, 1: e183146. PMID: 30646225, PMCID: PMC6324449, DOI: 10.1001/jamanetworkopen.2018.3146.Peer-Reviewed Original ResearchConceptsCancer death ratesDeath rateHigh-income countiesCancer disparitiesPossible mediatorsAge-standardized cancer death ratesLow-income countiesCross-sectional studyClinical care factorsIncome-related disparitiesNon-Hispanic blacksHealth risk behaviorsLow-quality careUS countiesPhysical inactivityCare factorsMAIN OUTCOMEFair healthDeath recordsMedian household incomeMedian incomeHealth StatisticsRisk behaviorsHealth policyCounty income levels
2016
Modeling risk of occupational zoonotic influenza infection in swine workers
Paccha B, Jones RM, Gibbs S, Kane MJ, Torremorell M, Neira-Ramirez V, Rabinowitz PM. Modeling risk of occupational zoonotic influenza infection in swine workers. Journal Of Occupational And Environmental Hygiene 2016, 13: 577-587. PMID: 26950677, DOI: 10.1080/15459624.2016.1159688.Peer-Reviewed Original ResearchConceptsRisk of infectionZoonotic influenza infectionSwine workersInfluenza infectionInfluenza strainsN95 respiratorsInfectivity of IAVNovel influenza strainsOutbreak of influenzaTransmission of influenzaLow-dose exposureHuman health care settingsHealth care settingsUse of respiratorsPrevious infectionPolymerase chain reactionIAV exposureCare settingsPandemic potentialPreventive programsPartial immunityZoonotic infectionInfectionZoonotic transmissionExposure of workers
2015
Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years
Torgerson PR, Hagan JE, Costa F, Calcagno J, Kane M, Martinez-Silveira MS, Goris MG, Stein C, Ko AI, Abela-Ridder B. Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years. PLOS Neglected Tropical Diseases 2015, 9: e0004122. PMID: 26431366, PMCID: PMC4591975, DOI: 10.1371/journal.pntd.0004122.Peer-Reviewed Original ResearchConceptsDisability Adjusted Life YearsGlobal burdenAdjusted Life YearsLife yearsResource-poor tropical countriesHighest burden estimatesSum of YLLsBurden of leptospirosisSignificant health burdenLife-threatening diseaseYears of lifeDiverse epidemiological settingsGBD 2010Febrile illnessDisease burdenHealth burdenBurden estimatesLife LostMortality rateUrban slum dwellersDisease estimatesEpidemiological settingsTotal burdenLikely sequelaeLeptospirosisGlobal Morbidity and Mortality of Leptospirosis: A Systematic Review
Costa F, Hagan JE, Calcagno J, Kane M, Torgerson P, Martinez-Silveira MS, Stein C, Abela-Ridder B, Ko AI. Global Morbidity and Mortality of Leptospirosis: A Systematic Review. PLOS Neglected Tropical Diseases 2015, 9: e0003898. PMID: 26379143, PMCID: PMC4574773, DOI: 10.1371/journal.pntd.0003898.Peer-Reviewed Original ResearchConceptsCase fatality ratioDisease morbidityFatality ratioSystematic reviewMortality of leptospirosisPulmonary hemorrhage syndromeBurden of leptospirosisLife-threatening diseaseDiverse epidemiological settingsResource-poor countriesNumber of deathsHigh morbidityGlobal morbidityGBD regionsGlobal burdenMorbidityZoonotic causesHaemorrhagic feverMortality studyUrban slum dwellersImportant causeDisease statusEpidemiological settingsDisease incidenceWHO regions
2014
Proximity to Natural Gas Wells and Reported Health Status: Results of a Household Survey in Washington County, Pennsylvania
Rabinowitz PM, Slizovskiy IB, Lamers V, Trufan SJ, Holford TR, Dziura JD, Peduzzi PN, Kane MJ, Reif JS, Weiss TR, Stowe MH. Proximity to Natural Gas Wells and Reported Health Status: Results of a Household Survey in Washington County, Pennsylvania. Environmental Health Perspectives 2014, 123: 21-26. PMID: 25204871, PMCID: PMC4286272, DOI: 10.1289/ehp.1307732.Peer-Reviewed Original ResearchConceptsHealth symptomsUpper respiratory symptomsPublic health impactRespiratory symptomsNeurological symptomsSymptom SurveyRespiratory conditionsSkin conditionsHypothesis generatingHealth statusSymptomsFurther studiesGastrointestinal conditionsHealth impactsHousehold educationPrevalenceWashington CountyHousehold proximityPersonsSmokingWater exposureHousehold surveyWork typeComparison of ARIMA and Random Forest time series models for prediction of avian influenza H5N1 outbreaks
Kane MJ, Price N, Scotch M, Rabinowitz P. Comparison of ARIMA and Random Forest time series models for prediction of avian influenza H5N1 outbreaks. BMC Bioinformatics 2014, 15: 276. PMID: 25123979, PMCID: PMC4152592, DOI: 10.1186/1471-2105-15-276.Peer-Reviewed Original ResearchMultiple types of motives don't multiply the motivation of West Point cadets
Wrzesniewski A, Schwartz B, Cong X, Kane M, Omar A, Kolditz T. Multiple types of motives don't multiply the motivation of West Point cadets. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 10990-10995. PMID: 24982165, PMCID: PMC4121823, DOI: 10.1073/pnas.1405298111.Peer-Reviewed Original ResearchConceptsWest Point cadetsInstrumental motivesInternal motivesEarly career promotionsOccupational contextNegative outcomesCareer outcomesSame actionPositive outcomesCareer promotionMotivationCadetsMultiple motifsSingle motiveField contextMilitary serviceContextResearchMultiple typesOutcomesMotivePeopleOfficersDifferent typesOfficer services