2020
Two‐stage randomized trial design for testing treatment, preference, and self‐selection effects for count outcomes
Shi Y, Cameron B, Gu X, Kane M, Peduzzi P, Esserman DA. Two‐stage randomized trial design for testing treatment, preference, and self‐selection effects for count outcomes. Statistics In Medicine 2020, 39: 3653-3683. PMID: 32875582, DOI: 10.1002/sim.8686.Peer-Reviewed Original ResearchConceptsTrial designPatient preferencesPatient-centered treatment strategiesTreatment effectsTraditional clinical trial designClinical trial designEnd of lifeUse of antimicrobialsTreatment strategiesHealthcare providersPatient psychologyTesting treatmentsTwo-stage designOutcomesParticular treatmentTreatmentBinary outcomesCount outcomesTrials
2019
A two‐stage phase II clinical trial design with nested criteria for early stopping and efficacy
DeVeaux M, Kane M, Wei W, Zelterman D. A two‐stage phase II clinical trial design with nested criteria for early stopping and efficacy. Pharmaceutical Statistics 2019, 18: 700-713. PMID: 31507079, PMCID: PMC6996237, DOI: 10.1002/pst.1965.Peer-Reviewed Original Research