Whole-genome Sequencing Association Analysis of Quantitative Platelet Traits in A Large Cohort of β-thalassemia
Wang X, Zhang Q, Chen X, Huang Y, Zhang W, Liao L, Zhang X, Huang B, Huang Y, Ye Y, Song M, Lao J, Chen J, Feng X, Long X, Liu Z, Zhu W, Yu L, Fan C, Tang D, Zhong T, Fang M, Li C, Niu C, Huang L, Lin B, Hua X, Jin X, Li Z, Xu X. Whole-genome Sequencing Association Analysis of Quantitative Platelet Traits in A Large Cohort of β-thalassemia. Genomics Proteomics & Bioinformatics 2024, qzae065. PMID: 39331630, DOI: 10.1093/gpbjnl/qzae065.Peer-Reviewed Original ResearchPlatelet traitsAnalysis of whole-genome sequencing dataWhole-genome sequencing dataFunctional annotation dataGenotype-phenotype association studiesRare variantsLack of genetic studiesMean platelet volumeNoncoding genomeWhole genomeSequence dataAssociation studiesMultiple genesGenetic studiesB-thalassemia patientsB-thalassemiaPhenotypic heterogeneityIntegrated analysisTraitsMissenseGenesPotential targetVariantsRV analysisGenome