2024
The impact of emergency guidance to the COVID‐19 pandemic on treatment entry, retention and mortality among patients on methadone in Ukraine
Ivasiy R, Madden L, Meteliuk A, Machavariani E, Ahmad B, Zelenev A, Desai M, Bromberg D, Polonsky M, de Leon S, Farnum S, Islam Z, Altice F. The impact of emergency guidance to the COVID‐19 pandemic on treatment entry, retention and mortality among patients on methadone in Ukraine. Addiction 2024, 119: 1585-1596. PMID: 38807448, DOI: 10.1111/add.16565.Peer-Reviewed Original ResearchOpioid agonist therapyTake-home dosesCOVID-19 guidancePre-COVID cohortAgonist therapyOptimal doseTreatment retentionEmergency guidanceEffective HIV prevention strategiesAdult HIV prevalenceHIV prevention strategiesMinistry of HealthImprove treatment retentionMethadone dosePatient survivalTime-dependent predictorsProspective cohortHIV prevalencePredictors of treatment retentionGovernmental clinicsPrimary outcomeHazard ratioPatient enrollmentPatientsMethadone patients
2023
Systematic review of inferior vena cava atresia
Saab K, Brahmandam A, Brackett A, Desai M, Dardik A, Guzman R, Chaar C. Systematic review of inferior vena cava atresia. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 11: 1253-1264. PMID: 37453547, DOI: 10.1016/j.jvsv.2023.07.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDeep vein thrombosisIVC atresiaCongenital anomaliesLeg painMost patientsDevelopment of DVTSystematic reviewAcceptable mid-term resultsInferior vena cava atresiaEndovascular surgical interventionsMortality of patientsOutcomes of patientsMid-term resultsRare venous anomalyTerms of patencyVein thrombosisSymptomatic reliefVenous anomaliesIliac veinInferior venaSurgical interventionMean ageTreatment groupsPatientsAtresia
2022
Preimplantation genetic testing for aneuploidy: challenges in clinical practice
Yang H, DeWan A, Desai M, Vermund S. Preimplantation genetic testing for aneuploidy: challenges in clinical practice. Human Genomics 2022, 16: 69. PMID: 36536471, PMCID: PMC9764701, DOI: 10.1186/s40246-022-00442-8.Peer-Reviewed Original ResearchConceptsPreimplantation genetic testingGenetic testingFetal disordersReproductive centerClinical practiceDefinitive guidelinesDrug AdministrationScreening testCurrent professional guidelinesDisease riskDiagnostic testsMosaic embryosProfessional guidelinesBlastocyst stagePGTAneuploidyAppropriate agenciesGenetic disease riskGuidelinesPatientsAdministration
2021
Expansion of a national differentiated service delivery model to support people living with HIV and other chronic conditions in South Africa: a descriptive analysis
Liu L, Christie S, Munsamy M, Roberts P, Pillay M, Shenoi SV, Desai MM, Linnander EL. Expansion of a national differentiated service delivery model to support people living with HIV and other chronic conditions in South Africa: a descriptive analysis. BMC Health Services Research 2021, 21: 463. PMID: 34001123, PMCID: PMC8127180, DOI: 10.1186/s12913-021-06450-z.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesDifferentiated service delivery modelsChronic conditionsChronic diseasesCentral Chronic Medicine DispensingLargest antiretroviral therapy (ART) programmeService delivery modelsManagement of HIVType of medicationAntiretroviral therapy programsHIV service deliveryChronic disease conditionsResource-limited settingsMedicine DispensingMixed-methods evaluationDelivery modelHealth districtHealth facilitiesNoncommunicable diseasesHIVPatientsPatient volumeTherapy programMedicationsDisease
2019
Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study.
Uribe-Restrepo AF, Prieto MD, Cossio A, Desai M, Castro M. Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study. American Journal Of Tropical Medicine And Hygiene 2019, 100: 306-310. PMID: 30628567, PMCID: PMC6367628, DOI: 10.4269/ajtmh.18-0643.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntimonyAntiprotozoal AgentsChildColombiaCross-Sectional StudiesCryotherapyFemaleHumansHyperthermia, InducedLeishmania braziliensisLeishmania guyanensisLeishmaniasis, CutaneousMaleMiddle AgedParomomycinPentamidinePractice Guidelines as TopicSeverity of Illness IndexConceptsLocal therapyPan American Health OrganizationCutaneous leishmaniasisWorld Health OrganizationIndividualized risk-benefit assessmentCases of CLHealth OrganizationProportion of patientsLarge referral centerRisk-benefit assessmentDifferent treatment guidelinesMaximum lesion sizeReferral centerTreatment guidelinesSystemic drugsWHO criteriaCL patientsSectional studyLeishmania VianniaHigh burdenSevere casesLower riskLesion sizePatientsMild presentation
2017
Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis
Martínez-Valencia AJ, Daza-Rivera CF, Rosales-Chilama M, Cossio A, Rincón E, Desai MM, Saravia NG, Gómez MA. Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis. PLOS Neglected Tropical Diseases 2017, 11: e0005713. PMID: 28704369, PMCID: PMC5526576, DOI: 10.1371/journal.pntd.0005713.Peer-Reviewed Original ResearchConceptsCutaneous leishmaniasisParasite persistencePercent of patientsInitiation of treatmentEnd of treatmentViability of LeishmaniaDisease reactivationTonsillar mucosaClinical cureClinical resolutionTreatment initiationProtective immunityMeglumine antimoniatePersistent infectionMucosal tissuesPrevious episodesTherapeutic cureParasitological factorsProtective factorsPatientsParasitological parametersTreatmentLeishmaniasisWeeksHigher proportion
2015
The Value of Continuous ST-Segment Monitoring in the Emergency Department
Bovino LR, Funk M, Pelter MM, Desai MM, Jefferson V, Andrews LK, Forte K. The Value of Continuous ST-Segment Monitoring in the Emergency Department. Advanced Emergency Nursing Journal 2015, 37: 290-300. PMID: 26509726, PMCID: PMC4644066, DOI: 10.1097/tme.0000000000000080.Peer-Reviewed Original ResearchConceptsContinuous ST-segment monitoringAcute coronary syndromeST-segment monitoringEmergency departmentAdverse eventsDiagnostic accuracyRisk-stratified analysisLikelihood ratioSingle emergency departmentHigh-risk participantsCoronary syndromeElectrocardiographic monitoringMedian timeTroponin (HEART) scoreMyocardial ischemiaRisk factorsHigh riskDiagnostic benefitIschemiaIntervention phaseDiagnosisBedside monitorsInfarctionPatientsSymptomsObesity not associated with severity among hospitalized adults with seasonal influenza virus infection
Braun ES, Crawford FW, Desai MM, Meek J, Kirley PD, Miller L, Anderson EJ, Oni O, Ryan P, Lynfield R, Bargsten M, Bennett NM, Lung KL, Thomas A, Mermel E, Lindegren ML, Schaffner W, Price A, Chaves SS. Obesity not associated with severity among hospitalized adults with seasonal influenza virus infection. Infection 2015, 43: 569-575. PMID: 26148927, DOI: 10.1007/s15010-015-0802-x.Peer-Reviewed Original ResearchConceptsSeasonal influenza virus infectionMultivariate logistic regression modelSeasonal influenza severityLaboratory-confirmed influenzaRisk of pneumoniaInfluenza virus infectionLogistic regression modelsHospitalized adultsICU admissionObese patientsSevere obesityInfluenza severityArtificial ventilationVirus infectionWeight categoriesObesityPneumoniaSeverityRegression modelsAdultsUnderweightPatientsAdmissionInfectionInfluenzaRisk of Stent Thrombosis and Major Bleeding with Bivalirudin Compared with Active Control: A Systematic Review and Meta-analysis of Randomized Trials
Kianoush S, Bikdeli B, Desai MM, Eikelboom JW. Risk of Stent Thrombosis and Major Bleeding with Bivalirudin Compared with Active Control: A Systematic Review and Meta-analysis of Randomized Trials. Thrombosis Research 2015, 136: 1087-1098. PMID: 26077961, DOI: 10.1016/j.thromres.2015.06.001.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionDefinite stent thrombosisMajor bleedingStent thrombosisCause mortalityMyocardial infarctionTrials of bivalirudinUse of bivalirudinAcute myocardial infarctionCoronary interventionCardiac deathRandomized trialsMAIN OUTCOMESimilar riskBivalirudinBleedingLower riskThrombosisMeta-AnalysisSystematic reviewPatientsMortalityTrialsInfarctionRisk
2014
Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011
Mody PS, Wang Y, Geirsson A, Kim N, Desai MM, Gupta A, Dodson JA, Krumholz HM. Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011. Circulation Cardiovascular Quality And Outcomes 2014, 7: 920-928. PMID: 25336626, PMCID: PMC4380171, DOI: 10.1161/circoutcomes.114.001140.Peer-Reviewed Original ResearchHospital variation in risk-standardized hospital admission rates from US EDs among adults
Capp R, Ross JS, Fox JP, Wang Y, Desai MM, Venkatesh AK, Krumholz HM. Hospital variation in risk-standardized hospital admission rates from US EDs among adults. The American Journal Of Emergency Medicine 2014, 32: 837-843. PMID: 24881514, DOI: 10.1016/j.ajem.2014.03.033.Peer-Reviewed Original ResearchConceptsHospital admission ratesEmergency departmentAdmission ratesClinical characteristicsED visitsHospital factorsClinical factorsAdult ED visitsUS emergency departmentsHospital teaching statusCross-sectional analysisPatient characteristicsHospital admissionHospital variationPatientsTeaching statusHospitalED dataVisitsRepresentative sampleAdultsRural locationsAdmissionFactorsNational variationsAn assessment of health-care students' attitudes toward patients with or at high risk for HIV: implications for education and cultural competency
Jin H, Earnshaw VA, Wickersham JA, Kamarulzaman A, Desai MM, John J, Altice FL. An assessment of health-care students' attitudes toward patients with or at high risk for HIV: implications for education and cultural competency. AIDS Care 2014, 26: 1223-1228. PMID: 24625279, PMCID: PMC4089975, DOI: 10.1080/09540121.2014.894616.Peer-Reviewed Original ResearchConceptsHealth care studentsMSM patientsVulnerable populationsFuture HIV preventionHealth care providersProfessional health-care studentsMultiple clinical contextsHealth care students' attitudesPatient groupGeneral patientsHIV preventionInternet-based surveyHigh riskHIVPatientsPWIDEffective interventionsTreatment effortsClinical contextGroup comparisonsDental studentsGroup differencesMean scoreSignificant differencesSurvey invitationUsual Source of Care and Outcomes Following Acute Myocardial Infarction
Spatz ES, Sheth SD, Gosch KL, Desai MM, Spertus JA, Krumholz HM, Ross JS. Usual Source of Care and Outcomes Following Acute Myocardial Infarction. Journal Of General Internal Medicine 2014, 29: 862-869. PMID: 24553957, PMCID: PMC4026492, DOI: 10.1007/s11606-014-2794-0.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionUsual sourceMyocardial infarctionMortality rateBaseline risk factorsAcute clinical eventsMain outcome measuresAMI severityAMI patientsMultivariable analysisKey ResultsAmongClinical eventsSocio-demographic characteristicsRisk factorsOutcome measuresReadmissionHigh mortalityPatientsMortalityCareMonthsInfarctionAdultsOutcomesAssociation
2013
Characteristics of Medicaid enrollees with frequent ED use
Capp R, Rosenthal MS, Desai MM, Kelley L, Borgstrom C, Cobbs-Lomax DL, Simonette P, Spatz ES. Characteristics of Medicaid enrollees with frequent ED use. The American Journal Of Emergency Medicine 2013, 31: 1333-1337. PMID: 23850143, DOI: 10.1016/j.ajem.2013.05.050.Peer-Reviewed Original ResearchConceptsFrequent ED usersFrequent ED useED usersMedicaid enrolleesED visitsED useFrequent emergency department visitsCommon ED diagnosesEmergency department visitsChronic medical conditionsPrimary care providersAlcohol-related disordersAbdominal painClinical characteristicsDepartment visitsCommon diagnosisSingle centerRetrospective studyPrimary careInsurance typeED diagnosisMedical conditionsCare providersAlcohol abusePatientsAssociations Between Mental Health and Surgical Outcomes Among Women Undergoing Mastectomy for Cancer
Fox JP, Philip EJ, Gross CP, Desai RA, Killelea B, Desai MM. Associations Between Mental Health and Surgical Outcomes Among Women Undergoing Mastectomy for Cancer. The Breast Journal 2013, 19: 276-284. PMID: 23521554, DOI: 10.1111/tbj.12096.Peer-Reviewed Original ResearchConceptsMental health conditionsInvasive breast cancerBreast cancerInpatient mastectomyHealth conditionsPsychiatric diagnosisSubstance abuseHigher average costsRisk of complicationsBreast cancer patientsNationwide Inpatient SampleSerious psychological distressSubstance use disordersHospital outcomesClinical characteristicsPerioperative periodPoor outcomeSurgical outcomesCancer careCancer patientsInpatient SampleUse disordersMastectomyLinear regression analysisPatients
2012
293 National Pattern of Risk-Standardized Emergency Department Hospital Admission Rates for Adult Patients
Capp R, Fox J, Desai M, Wang Y, Krumholz H. 293 National Pattern of Risk-Standardized Emergency Department Hospital Admission Rates for Adult Patients. Annals Of Emergency Medicine 2012, 60: s104. DOI: 10.1016/j.annemergmed.2012.06.271.Peer-Reviewed Original ResearchOutcomes for Mitral Valve Surgery Among Medicare Fee-for-Service Beneficiaries, 1999 to 2008
Dodson JA, Wang Y, Desai MM, Barreto-Filho JA, Sugeng L, Hashim SW, Krumholz HM. Outcomes for Mitral Valve Surgery Among Medicare Fee-for-Service Beneficiaries, 1999 to 2008. Circulation Cardiovascular Quality And Outcomes 2012, 5: 298-307. PMID: 22576847, PMCID: PMC3400109, DOI: 10.1161/circoutcomes.112.966077.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChi-Square DistributionFee-for-Service PlansFemaleHealthcare DisparitiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHospitalizationHumansLinear ModelsMaleMedicareMitral ValveOdds RatioPatient ReadmissionQuality ImprovementRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsMitral valve surgeryValve surgeryMitral valve repairFFS patientsHospitalization ratesValve repairMedicare feeMedicare Standard Analytic FilesMedicare FFS patientsRisk-standardized ratesProportion of patientsStandard Analytic FilesVital Status filesNational surveillance dataMedicare administrative dataSubstantial morbidityMortality outcomesService patientsAnalytic FilesMortality riskMortality rateSurgeryPatientsDenominator fileReadmission
2011
Correlates of religious, supernatural and psychosocial causal beliefs about depression among Latino immigrants in primary care
Caplan S, Paris M, Whittemore R, Desai M, Dixon J, Alvidrez J, Escobar J, Scahill L. Correlates of religious, supernatural and psychosocial causal beliefs about depression among Latino immigrants in primary care. Mental Health Religion & Culture 2011, 14: 589-611. DOI: 10.1080/13674676.2010.497810.Peer-Reviewed Original ResearchPsychosocial causal beliefsCausal beliefsPrimary care patientsCross-sectional studyCausal attributionsExploratory factor analysisPersonal transgressionsLatino immigrantsCare patientsBeliefs ScalePrimary carePsychosocial factorsHealth knowledgeDepressive symptomsMultivariate analysisSomatic symptomsEthnic identitySpecific interventionsFactor analysisBeliefsReligious explanationsPatientsDepressionSymptomsMalevolent forcesTrends in Comorbidity, Disability, and Polypharmacy in Heart Failure
Wong CY, Chaudhry SI, Desai MM, Krumholz HM. Trends in Comorbidity, Disability, and Polypharmacy in Heart Failure. The American Journal Of Medicine 2011, 124: 136-143. PMID: 21295193, PMCID: PMC3237399, DOI: 10.1016/j.amjmed.2010.08.017.Peer-Reviewed Original ResearchConceptsProportion of patientsHeart failureSelf-reported heart failureHeart failure populationComorbid chronic conditionsNumber of comorbiditiesNutrition Examination SurveyCare of patientsPrevalence of disabilityPhenotype of patientsComplexity of patientsMedication useRecent patientsFunctional disabilityExamination SurveyFailure populationPhysical functionPrescription medicationsPatient preferencesChronic conditionsNational HealthPatient's abilityComorbiditiesPatientsOlder individuals
2010
Complementary and Alternative Medicine Use in Chronic Liver Disease Patients
Ferrucci LM, Bell BP, Dhotre KB, Manos MM, Terrault NA, Zaman A, Murphy RC, VanNess GR, Thomas AR, Bialek SR, Desai MM, Sofair AN. Complementary and Alternative Medicine Use in Chronic Liver Disease Patients. Journal Of Clinical Gastroenterology 2010, 44: e40-e45. PMID: 19779363, PMCID: PMC3730290, DOI: 10.1097/mcg.0b013e3181b766ed.Peer-Reviewed Original ResearchConceptsChronic liver disease patientsLiver disease patientsAlternative medicine useCAM useCAM therapiesDisease patientsMedicine useConventional treatmentPopulation-based surveillance studyLogistic regression analysisPopulation-based sampleCLD etiologyClinical characteristicsCurrent usePrior hospitalizationIndependent correlatesMedical recordsClinical informationSurveillance studyPatientsTherapyDietary supplementsPotential predictorsHealth concernHerbal medicine