Venus: An efficient virus infection detection and fusion site discovery method using single-cell and bulk RNA-seq data
Lee CY, Chen Y, Duan Z, Xu M, Girgenti MJ, Xu K, Gerstein M, Zhang J. Venus: An efficient virus infection detection and fusion site discovery method using single-cell and bulk RNA-seq data. PLOS Computational Biology 2022, 18: e1010636. PMID: 36301997, PMCID: PMC9642901, DOI: 10.1371/journal.pcbi.1010636.Peer-Reviewed Original ResearchConceptsHBV-hepatocellular carcinomaAntiretroviral therapyHIV infectionImmune cellsT cellsViral pathophysiologyNeurological patientsNovel targetVirusInfection detectionVirus of interestPotential pathogensVirus detectionBulk RNA-seq dataCell typesViral transcriptsSingle-cell sequencingRNA-seq dataPublic healthcareCellsHIVPatientsCarcinomaPathogensPathophysiology