2020
Herbal Medicines in Glaucoma Treatment.
Ige M, Liu J. Herbal Medicines in Glaucoma Treatment. The Yale Journal Of Biology And Medicine 2020, 93: 347-353. PMID: 32607093, PMCID: PMC7309662.Peer-Reviewed Original ResearchMeSH KeywordsBiological ProductsGinkgo bilobaGlaucomaHumansIntraocular PressurePlants, MedicinalTreatment OutcomeVaccinium myrtillusConceptsCourse of glaucomaIntraocular pressureGlaucoma patientsGlaucoma treatmentRetinal ganglion cell deathHerbal medicineMedical marijuanaGanglion cell deathStandard therapeutic agentsSignificant adverse effectsCurrent standardGinkgo bilobaSurgical therapyGlaucoma managementIrreversible blindnessGlaucomaAlternative medicineLarger studyHerbal remediesTherapeutic agentsAddictive potentialAdverse effectsLonger durationPatientsShort duration
2017
Novel Pharmacologic Candidates for Treatment of Primary Open-Angle Glaucoma.
Lu LJ, Tsai JC, Liu J. Novel Pharmacologic Candidates for Treatment of Primary Open-Angle Glaucoma. The Yale Journal Of Biology And Medicine 2017, 90: 111-118. PMID: 28356898, PMCID: PMC5369028.Peer-Reviewed Original ResearchMeSH KeywordsGlaucoma, Open-AngleHumansIntraocular PressureIsoquinolinesOxepinsProstaglandins F, SyntheticRho-Associated KinasesSulfonamidesConceptsPrimary open-angle glaucomaOpen-angle glaucomaIntraocular pressureProstaglandin analoguesDrug-related side effectsCurrent medical treatment optionsLowering of IOPTarget intraocular pressureMedical treatment optionsVisual field lossAlpha-adrenergic agonistsNew pharmacologic optionsLower intraocular pressureMultiple daily administrationBeta-adrenergic antagonistsAdenosine receptor agonistsLow patient complianceAqueous humor outflowRho-kinase inhibitorTrabecular meshwork outflow pathwaysLatanoprostene bunodPharmacologic optionsPharmacologic treatmentTopical medicationsDaily administration
2016
Effect of supine body position on central corneal thickness
Maslin JS, Teng CC, Chadha N, Liu J. Effect of supine body position on central corneal thickness. Clinical And Experimental Ophthalmology 2016, 44: 678-683. PMID: 26991869, DOI: 10.1111/ceo.12742.Peer-Reviewed Original ResearchConceptsCentral corneal thicknessOpen-angle glaucoma patientsSupine body positionHealthy subjectsGlaucoma patientsSupine positioningMin supineCorneal thicknessBody positionLaterality of eyeAngle glaucoma patientsUniversity Eye ClinicCross-sectional studyGlaucoma groupEye clinicSupine positionSitting positionUltrasound pachymeterPatientsSignificant differencesSupineSimilar ratesSubjectsConsecutive measurementsEyesNeurodegeneration and Neuroprotection in Glaucoma.
Gauthier AC, Liu J. Neurodegeneration and Neuroprotection in Glaucoma. The Yale Journal Of Biology And Medicine 2016, 89: 73-9. PMID: 27505018, PMCID: PMC4797839.Peer-Reviewed Original ResearchConceptsCentral nervous system degenerative disorderOptic nerve degenerationRetinal ganglion cellsLateral geniculate nucleusAdenosine receptor antagonistIntraocular pressureNerve degenerationNeurotrophic factorReceptor antagonistGanglion cellsGlaucoma progressionDisease progressionIrreversible blindnessGeniculate nucleusNew therapiesVisual cortexDegenerative disordersAxonal transportCell therapyGlaucomaOxidative stressTherapyDiseaseNeuroprotectionNeurodegeneration