2020
Herbal Medicines in Glaucoma Treatment.
Ige M, Liu J. Herbal Medicines in Glaucoma Treatment. The Yale Journal Of Biology And Medicine 2020, 93: 347-353. PMID: 32607093, PMCID: PMC7309662.Peer-Reviewed Original ResearchConceptsCourse of glaucomaIntraocular pressureGlaucoma patientsGlaucoma treatmentRetinal ganglion cell deathHerbal medicineMedical marijuanaGanglion cell deathStandard therapeutic agentsSignificant adverse effectsCurrent standardGinkgo bilobaSurgical therapyGlaucoma managementIrreversible blindnessGlaucomaAlternative medicineLarger studyHerbal remediesTherapeutic agentsAddictive potentialAdverse effectsLonger durationPatientsShort duration
2017
Epigenetics and Signaling Pathways in Glaucoma
Gauthier AC, Liu J. Epigenetics and Signaling Pathways in Glaucoma. BioMed Research International 2017, 2017: 5712341. PMID: 28210622, PMCID: PMC5292191, DOI: 10.1155/2017/5712341.Peer-Reviewed Original ResearchConceptsPotential new therapeutic targetGeneration of fibrosisNovel therapeutic agentsNew therapeutic targetsAqueous humor drainageProapoptotic gene expressionRetinal neuronsIrreversible blindnessCommon causeHuman trialsTherapeutic targetAnimal modelsTrabecular meshworkTherapeutic agentsNeurodegenerative diseasesProsurvival factorBcl-2Rho-kinaseGlaucomaSignaling pathwaysPathway membersMAP kinaseGene expressionPathwayPreliminary success
2016
Neurodegeneration and Neuroprotection in Glaucoma.
Gauthier AC, Liu J. Neurodegeneration and Neuroprotection in Glaucoma. The Yale Journal Of Biology And Medicine 2016, 89: 73-9. PMID: 27505018, PMCID: PMC4797839.Peer-Reviewed Original ResearchConceptsCentral nervous system degenerative disorderOptic nerve degenerationRetinal ganglion cellsLateral geniculate nucleusAdenosine receptor antagonistIntraocular pressureNerve degenerationNeurotrophic factorReceptor antagonistGanglion cellsGlaucoma progressionDisease progressionIrreversible blindnessGeniculate nucleusNew therapiesVisual cortexDegenerative disordersAxonal transportCell therapyGlaucomaOxidative stressTherapyDiseaseNeuroprotectionNeurodegeneration
2015
Marijuana for Glaucoma: A Recipe for Disaster or Treatment?
Sun X, Xu CS, Chadha N, Chen A, Liu J. Marijuana for Glaucoma: A Recipe for Disaster or Treatment? The Yale Journal Of Biology And Medicine 2015, 88: 265-9. PMID: 26339209, PMCID: PMC4553646.Peer-Reviewed Original ResearchConceptsCannabis use disorderIntraocular pressureGlaucoma patientsGlaucoma treatmentAdverse effectsMost glaucoma patientsLower intraocular pressurePsychological adverse effectsTreatment of glaucomaNumerous adverse effectsSignificant adverse effectsWithdrawal symptomsPossible progressionUse disordersUse of marijuanaSubstance abuseMedical marijuanaRare circumstancesFurther studiesTreatmentPatientsGlaucomaCannabinoid moleculesMarijuanaDeleterious effectsResident and Fellow Glaucoma Surgical Experience Following the Tube Versus Trabeculectomy Study
Chadha N, Liu J, Teng CC. Resident and Fellow Glaucoma Surgical Experience Following the Tube Versus Trabeculectomy Study. Ophthalmology 2015, 122: 1953-1954. PMID: 25911055, DOI: 10.1016/j.ophtha.2015.03.009.Peer-Reviewed Original Research