2024
Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances
McCurdy L, Yip S, Worhunsky P, Zhai Z, Kim S, Strathearn L, Potenza M, Mayes L, Rutherford H. Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances. Journal Of Psychiatric Research 2024, 171: 126-133. PMID: 38277872, PMCID: PMC10922955, DOI: 10.1016/j.jpsychires.2024.01.024.Peer-Reviewed Original ResearchConceptsResponses to infant stimuliInfant stimuliMaternal behaviorAffective processesBrain regionsPsychological processesEmotional responsesFunctional magnetic resonance imagingPotential neural targetsInfant emotional expressionsMaternal emotional responsivenessSubstance-use statusAssociated with difficultiesSocial-emotional developmentInfant social-emotional developmentMaternal substance useInfant facesCognitive processesImprove child outcomesEmotional expressionEmotional intensityNeural targetsSubstance useGroups of mothersChild outcomes
2023
Maternal psychological risk and the neural correlates of infant face processing: A latent profile analysis
Wall K, Penner F, Dell J, Lowell A, Potenza M, Mayes L, Rutherford H. Maternal psychological risk and the neural correlates of infant face processing: A latent profile analysis. Developmental Psychobiology 2023, 66: e22445. PMID: 38131237, PMCID: PMC10783861, DOI: 10.1002/dev.22445.Peer-Reviewed Original ResearchParticipation in an Attachment-Based Home Visiting Program Is Associated with Lower Child Salivary C-Reactive Protein Levels at Follow-Up
Tobón A, Condon E, Slade A, Holland M, Mayes L, Sadler L. Participation in an Attachment-Based Home Visiting Program Is Associated with Lower Child Salivary C-Reactive Protein Levels at Follow-Up. Journal Of Developmental And Behavioral Pediatrics 2023, 44: e292-e299. PMID: 37126599, PMCID: PMC10353420, DOI: 10.1097/dbp.0000000000001180.Peer-Reviewed Original ResearchConceptsSalivary inflammatory biomarkersInflammatory biomarkersEarly childhood adversityC-reactive protein levelsChildhood adversitySalivary cytokine levelsEarly adversityMaternal-child dyadsHome Visiting ProgramSalivary CRP levelsMother-infant dyadsBlack/African AmericanHispanics/LatinosRCT completionCRP levelsCytokine levelsFollow-upSalivary specimensVisiting ProgramEarly interventionNegative psychosocial outcomesPsychosocial outcomesLong-term biological effectsProtein levelsMtbLong-term neurocognitive outcomes in 204 single-suture craniosynostosis patients
Junn A, Long A, Hauc S, Almeida M, Alper D, Rivera J, Mayes L, Persing J, Alperovich M. Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients. Child's Nervous System 2023, 39: 1921-1928. PMID: 36877207, DOI: 10.1007/s00381-023-05908-1.Peer-Reviewed Original ResearchConceptsFull Scale IQVisuomotor integrationVisual perceptionVerbal IQNeurocognitive testingVisual perception scoresHigher scoresLong-term neurocognitive outcomesCognitive profileWhite matter connectionsNeurocognitive deficitsIQPerception scoresMean IQNeurocognitive outcomesFrontal lobeLower scoresMotor controlMotor coordinationPerceptionNon-syndromic craniosynostosisUnicoronal synostosisScoresChildren 6
2003
Emotion regulation behavior during a separation procedure in 18-month-old children of mothers using cocaine and other drugs
MOLITOR A, MAYES LC, WARD A. Emotion regulation behavior during a separation procedure in 18-month-old children of mothers using cocaine and other drugs. Development And Psychopathology 2003, 15: 39-54. PMID: 12848434, DOI: 10.1017/s0954579403000038.Peer-Reviewed Original ResearchConceptsCocaine-using mothersCocaine useDrug useMaternal cocaine useMaternal drug useCocaine-exposed childrenPositive historyMaternal groupsEmotional engagementMaternal behaviorPossible impairmentEmotional regulationRisk childrenMothersChildrenEmotion regulation behaviorsChildren's emotional regulationPositive emotional engagementFace of stressMaternal disengagementMarijuanaChildren's reactivityEmotional expressionNegative reactivityChild constructs
2001
The Twin Poles of Order and Chaos
Mayes L. The Twin Poles of Order and Chaos. The Psychoanalytic Study Of The Child 2001, 56: 137-170. PMID: 12102010, DOI: 10.1080/00797308.2001.11800671.Peer-Reviewed Original ResearchConceptsDevelopmental perspectiveTheories of developmentPsychoanalytic developmental perspectiveLevel of fantasyPsychological developmentDevelopmental theoryChild developmentPsychoanalytic perspectiveConstant dialecticSystems theoryThird questionDiversity of theoriesGeneral systems theoryDifferent perspectivesPerspectiveTheoryTaskQuestionsAttitudesChildrenEpigenesisAdultsFantasyDisordersTwin poles
2000
A developmental perspective on the regulation of arousal states
Mayes L. A developmental perspective on the regulation of arousal states. Seminars In Perinatology 2000, 24: 267-279. PMID: 10975433, DOI: 10.1053/sper.2000.9121.Peer-Reviewed Original ResearchConceptsArousal regulationSensory cortical systemsDifferent neurochemical systemsCourse of developmentNeurobiological perspectiveDevelopmental perspectiveTraumatic experiencesCortical systemsCortical activationArousal stateCortical activityOrganizing constructArousal systemNeurochemical systemsBalance of inhibitoryExcitatory processesLevel of stimulationFacilitate coordinationCortexConstructsPerspectiveDynamic processExecutivesComplex interactionsExperienceThe mother-child interaction and clinical judgment during acute pediatric illnesses
McCarthy P, Freudigman K, Cicchetti D, Mayes L, Benitez J, Salloum S, Baron M, Fink H, Anderson R, LaCamera R. The mother-child interaction and clinical judgment during acute pediatric illnesses. The Journal Of Pediatrics 2000, 136: 809-817. PMID: 10839881, DOI: 10.1016/s0022-3476(00)22735-2.Peer-Reviewed Original ResearchConceptsIllness severityClinical judgmentEmotional Availability ScalesLow specificityMother-child interactionAcute Illness Observation ScalesAcute pediatric illnessesGreater resource useIll visitsAcute illnessMaternal social supportOptimal mother-child interactionIll childrenChild visitsPediatric illnessMaternal depressionMothers' judgmentsPaediatricians' judgementsIllnessDemographic characteristicsResource useSeverityInfant temperamentSense of competencePediatricians
1999
Developing brain and in utero cocaine exposure: Effects on neural ontogeny
MAYES L. Developing brain and in utero cocaine exposure: Effects on neural ontogeny. Development And Psychopathology 1999, 11: 685-714. PMID: 10624721, DOI: 10.1017/s0954579499002278.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureCocaine exposureNeural ontogenyNervous system ontogenyUtero cocaine exposureCNS ontogenyType of exposureMonoaminergic systemsMonoamine systemsPreclinical studiesCocaine effectsNeuropsychological effectsNervous systemPatterns of arousalPrimary siteNeural migrationCell proliferationYoung childrenTrophic roleCocaine-related effectsExposureBrainAttention regulationCandidate mechanismArousalPreoccupations and Behaviors Associated with Romantic and Parental Love: Perspectives on the Origin of Obsessive-Compulsive Disorder
Leckman J, Mayes L. Preoccupations and Behaviors Associated with Romantic and Parental Love: Perspectives on the Origin of Obsessive-Compulsive Disorder. Child And Adolescent Psychiatric Clinics Of North America 1999, 8: 635-665. PMID: 10442234, DOI: 10.1016/s1056-4993(18)30172-x.Peer-Reviewed Original ResearchDistress During the Induction of Anesthesia and Postoperative Behavioral Outcomes
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress During the Induction of Anesthesia and Postoperative Behavioral Outcomes. Anesthesia & Analgesia 1999, 88: 1042-1047.. DOI: 10.1213/00000539-199905000-00013.Peer-Reviewed Original ResearchDistress during the induction of anesthesia and postoperative behavioral outcomes.
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress during the induction of anesthesia and postoperative behavioral outcomes. Anesthesia & Analgesia 1999, 88: 1042-7. PMID: 10320165, DOI: 10.1097/00000539-199905000-00013.Peer-Reviewed Original ResearchAddressing Mental Health Needs of Infants and Young Children
Mayes L. Addressing Mental Health Needs of Infants and Young Children. Child And Adolescent Psychiatric Clinics Of North America 1999, 8: 209-224. PMID: 10202586, DOI: 10.1016/s1056-4993(18)30176-7.Peer-Reviewed Original ResearchConceptsYoung childrenChild psychiatryMental health interventionsMental health needsEarly brain developmentPsychological interventionsDiagnostic nosologyMental health servicesDevelopmental competencyBrain developmentClinical skillsChildrenFirst yearSkillsSocial workHealth servicesHealth interventionsHealth needsProfessional backgroundPsychologyMultiple viewpointsMultidisciplinary approachInterventionEarly childhood educationValence
1998
Incidence of Passive Exposure to Crack/Cocaine and Clinical Findings in Infants Seen in an Outpatient Service
Lustbader A, Mayes L, McGee B, Jatlow P, Roberts W. Incidence of Passive Exposure to Crack/Cocaine and Clinical Findings in Infants Seen in an Outpatient Service. Pediatrics 1998, 102: e5-e5. PMID: 9651457, DOI: 10.1542/peds.102.1.e5.Peer-Reviewed Original ResearchMeSH KeywordsCocaineConnecticutCrack CocaineEnvironmental MonitoringEnzyme Multiplied Immunoassay TechniqueEpidemiological MonitoringFemaleGas Chromatography-Mass SpectrometryHumansIncidenceInfantInfant, NewbornNarcoticsOutpatient Clinics, HospitalPregnancyPrenatal Exposure Delayed EffectsProspective StudiesRadioimmunoassayRespiratory Tract InfectionsRetrospective StudiesSubstance Abuse DetectionConceptsYears of ageCocaine exposureRespiratory symptomsIll infantsMedical carePassive exposureYale-New Haven HospitalMaternal drug historyRIA-positive samplesEnzyme-multiplied immunoassay techniqueLower respiratory symptomsUrine toxicology resultsUpper respiratory symptomsRoutine clinical indicationsCurrent National InstituteInner-city populationPositive urine resultsHealth care resourcesSamples of urineChart reviewClinical findingsClinical symptomsMedical visitsEmergency departmentBirth weightRegulation of arousal and attention in preschool children exposed to cocaine prenatally.
Mayes L, Grillon C, Granger R, Schottenfeld R. Regulation of arousal and attention in preschool children exposed to cocaine prenatally. Annals Of The New York Academy Of Sciences 1998, 846: 126-43. PMID: 9668402.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureArousal regulationRegulation of arousalCocaine exposureAged childrenCocaine-exposed childrenFace of noveltyOngoing information processingSubstance-abusing familiesAttention regulationCocaine-exposed infantsEmotional reactivityImpaired attentionStructured tasksNeurobehavioral findingsStressful situationsInformation processingHuman infantsNeurophysiological findingsPreschool childrenArousalSuch childrenStartle responseStress circuitsNeurobehavioral effectsRegulation of Arousal and Attention in Preschool Children Exposed to Cocaine Prenatally
Mayes L, Grillon C, Granger R, Schottenfeld R. Regulation of Arousal and Attention in Preschool Children Exposed to Cocaine Prenatally. Annals Of The New York Academy Of Sciences 1998, 846: 126-143. PMID: 29087549, DOI: 10.1111/j.1749-6632.1998.tb09731.x.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureArousal regulationRegulation of arousalCocaine exposureAged childrenCocaine-exposed childrenFace of noveltyOngoing information processingSubstance-abusing familiesAttention regulationCocaine-exposed infantsEmotional reactivityImpaired attentionStructured tasksNeurobehavioral findingsStressful situationsInformation processingHuman infantsNeurophysiological findingsPreschool childrenArousalSuch childrenStartle responseStress circuitsNeurobehavioral effects
1997
Maternal Attentiveness of Cocaine Abusers During Child—Based Assessments
Ball S, Mayes L, DeTeso J, Schottenfeld R. Maternal Attentiveness of Cocaine Abusers During Child—Based Assessments. American Journal On Addictions 1997, 6: 135-143. PMID: 9134075, DOI: 10.1111/j.1521-0391.1997.tb00562.x.Peer-Reviewed Original ResearchPremedication in the United States: A Status Report
Kain Z, Mayes L, Bell C, Weisman S, Hofstadter M, Rimar S. Premedication in the United States: A Status Report. Anesthesia & Analgesia 1997, 84: 427. DOI: 10.1213/00000539-199702000-00035.Peer-Reviewed Original ResearchConceptsSedative premedicationUse of premedicationHealth maintenance organization (HMO) penetrationYears of ageAge 3 yearsIndependent predictorsMultivariable analysisAnesthetic careSedative drugsPremedicationPhysician membersSedative premedicantsAge groupsLack of consensusPremedicantAdultsAmerican SocietyAnesthesiologistsHMO penetrationChildrenHMO participationUnited StatesSurvey studyMarked variationQuestionnairePremedication in the United States
Kain Z, Mayes L, Bell C, Weisman S, Hofstadter M, Rimar S. Premedication in the United States. Anesthesia & Analgesia 1997, 84: 427-432.. PMID: 9024042, DOI: 10.1097/00000539-199702000-00035.Peer-Reviewed Original ResearchConceptsSedative premedicationUse of premedicationHealth maintenance organization (HMO) penetrationYears of ageAge 3 yearsIndependent predictorsMultivariable analysisAnesthetic careSedative drugsPremedicationPhysician membersSedative premedicantsAge groupsLack of consensusPremedicantAdultsAmerican SocietyAnesthesiologistsHMO penetrationChildrenHMO participationUnited StatesSurvey studyMarked variationQuestionnaire
1996
Parental Presence during Induction of Anesthesia
Kain Z, Mayes L, Caramico L, Silver D, Spieker M, Nygren M, Anderson G, Rimar S. Parental Presence during Induction of Anesthesia. Anesthesiology 1996, 84: 1060-1067. PMID: 8623999, DOI: 10.1097/00000542-199605000-00007.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaSerum cortisol concentrationsLow baseline levelsParental presencePhysiologic measuresBaseline levelsCortisol concentrationsPreoperative behavioral interventionsMultivariate linear regression analysisOutpatient surgeryIntervention groupLinear regression analysisControl groupParent-absent groupBaseline temperamentAnesthesiaBehavioral interventionsChild's ageSignificant differencesChildrenRegression analysisInterventionLow trait anxietyTrait anxietyAnxiety