2024
Long-term exposure to wildland fire smoke PM2.5 and mortality in the contiguous United States
Ma Y, Zang E, Liu Y, Wei J, Lu Y, Krumholz H, Bell M, Chen K. Long-term exposure to wildland fire smoke PM2.5 and mortality in the contiguous United States. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2403960121. PMID: 39316057, PMCID: PMC11459178, DOI: 10.1073/pnas.2403960121.Peer-Reviewed Original ResearchConceptsWildland firesContiguous United StatesNonaccidental mortalityExposure to ambient fine particlesSmoke PM<sWildland fire smokeMoving average concentrationsAmbient fine particlesLong-term exposureAverage concentrationSmoke PMHealth risksFine particlesFire smokeTemporal confoundingHealth effectsKidney disease mortalityChronic kidney disease mortalityPublic health actionFireMortality rateUnited StatesDisease mortalityHealth actionsMortality outcomesFloods and cause-specific mortality in the United States during 2001-2020
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States during 2001-2020. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1705.Peer-Reviewed Original ResearchShort-term association between ambient ozone and onset of acute myocardial infarction of young patients: Results from the VIRGO study
Zhang S, Chu L, Lu Y, Krumholz H, Chen K. Short-term association between ambient ozone and onset of acute myocardial infarction of young patients: Results from the VIRGO study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0539.Peer-Reviewed Original ResearchSimulating desegregation through affordable housing development: An environmental health impact assessment of Connecticut zoning law
Prasanth S, Oloyede N, Zhang X, Chen K, Carrión D. Simulating desegregation through affordable housing development: An environmental health impact assessment of Connecticut zoning law. Health & Place 2024, 88: 103277. PMID: 38781859, PMCID: PMC11190844, DOI: 10.1016/j.healthplace.2024.103277.Peer-Reviewed Original ResearchNon-Hispanic white residentsEnvironmental health equityAmbient environmental exposuresHealth impact assessmentExposure-response functionsEnvironmental health impact assessmentHealth equityHealth inequalitiesNon-HispanicRate of deathExcess deathsWhite residentsEstimated deathsMortality impactLow-income residentsDesegregation policiesEnvironmental exposuresResidential segregationHousing targetsResidentsHousing developmentDeathSimulated movementHealthImpact assessmentAir pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries
Ma Y, Nobile F, Marb A, Dubrow R, Kinney P, Peters A, Stafoggia M, Breitner S, Chen K. Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries. Environment International 2024, 187: 108668. PMID: 38640613, DOI: 10.1016/j.envint.2024.108668.Peer-Reviewed Original ResearchConceptsMeteorological normalization techniqueAir pollution changesFine particulate matterImprove air qualityEmission control strategiesCentral-southern ItalyPollution changesParticulate matterRegion-specific estimatesAir qualityMeteorological impactsAir pollutionPollutionCOVID-19 lockdownModeling approachAirCaliforniaMortality changesConcentrationJiangsuEmissionTime trendsLocal characteristicsChinaMatterAssociation of exposure to extreme rainfall events with cause-specific mortality in North Carolina, US
Chan K, Ban J, Ma Y, Chen K. Association of exposure to extreme rainfall events with cause-specific mortality in North Carolina, US. Environmental Research Letters 2024, 19: 044006. DOI: 10.1088/1748-9326/ad2dd2.Peer-Reviewed Original ResearchCause-specific mortalityExtreme rainfall eventsDaily total precipitationRainfall eventsCounty-level mortality dataNorth Carolina countiesTime-series studyRisk of mortalityDaily rainfall measurementsNon-accidental diseasesNorth CarolinaMortality dataRespiratory mortalityExternal mortalityMortality riskRainfall measurementsTotal precipitationNon-accidentalRace groupsMeta-analysisCardiovascular diseaseRainfallStudy periodTwo-stage analysisNorthShort-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries
Ma Y, Nobile F, Marb A, Dubrow R, Stafoggia M, Breitner S, Kinney P, Chen K. Short-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries. JAMA Network Open 2024, 7: e2354607. PMID: 38427355, PMCID: PMC10907920, DOI: 10.1001/jamanetworkopen.2023.54607.Peer-Reviewed Original ResearchConceptsShort-term exposure to air pollutionExposure to air pollutionFine particulate matterCross-sectional studyAir pollutionFixed-effects modelParticulate matterShort-term exposure to PM2.5Short-term exposure to fine particulate matterNO2 concentrationsExposure to fine particulate matterMortality rateNitrogen dioxideSignificant effect modificationDaily PM2.5 concentrationsTime-varying confoundersExposure to PM2.5Health outcomesEstimate associationsMortality dataEffect modificationPM2.5 concentrationsMain OutcomesDay-to-dayCentral-southern ItalyImpact of population aging on future temperature-related mortality at different global warming levels
Chen K, de Schrijver E, Sivaraj S, Sera F, Scovronick N, Jiang L, Roye D, Lavigne E, Kyselý J, Urban A, Schneider A, Huber V, Madureira J, Mistry M, Cvijanovic I, Gasparrini A, Vicedo-Cabrera A. Impact of population aging on future temperature-related mortality at different global warming levels. Nature Communications 2024, 15: 1796. PMID: 38413648, PMCID: PMC10899213, DOI: 10.1038/s41467-024-45901-z.Peer-Reviewed Original ResearchPublished research on the human health implications of climate change between 2012 and 2021: cross sectional study
Bartlett V, Doernberg H, Mooghali M, Gupta R, Wallach J, Nyhan K, Chen K, Ross J. Published research on the human health implications of climate change between 2012 and 2021: cross sectional study. BMJ Medicine 2024, 3: e000627. PMID: 38352020, PMCID: PMC10862342, DOI: 10.1136/bmjmed-2023-000627.Peer-Reviewed Original ResearchHealth effects of climate changeHealth research fundingRandom sampleHealth effectsCross sectional studyPeer-reviewed researchWeb of ScienceGrey literatureHealth conditionsSectional studyInclusion criteriaRisk populationHealthHealth impactsHealth implicationsGoogle ScholarResearch articlesNational InstituteFunding sourcesPublication characteristicsResearch fundingPublished researchRiskDisproportionate focusPopulationOzone-related acute excess mortality projected to increase in the absence of climate and air quality controls consistent with the Paris Agreement
Domingo N, Fiore A, Lamarque J, Kinney P, Jiang L, Gasparrini A, Breitner S, Lavigne E, Madureira J, Masselot P, das Neves Pereira da Silva S, Sheng Ng C, Kyselý J, Guo Y, Tong S, Kan H, Urban A, Orru H, Maasikmets M, Pascal M, Katsouyanni K, Samoli E, Scortichini M, Stafoggia M, Hashizume M, Alahmad B, Diaz M, la Cruz Valencia C, Scovronick N, Garland R, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Ragettli M, Guo Y, Pan S, Colistro V, Bell M, Zanobetti A, Schwartz J, Schneider A, Vicedo-Cabrera A, Chen K. Ozone-related acute excess mortality projected to increase in the absence of climate and air quality controls consistent with the Paris Agreement. One Earth 2024, 7: 325-335. PMID: 38420618, PMCID: PMC7615682, DOI: 10.1016/j.oneear.2024.01.001.Peer-Reviewed Original ResearchClimate scenariosOzone-related deathsAir quality regulationsGround-level ozoneAcute mortalityAir quality controlCMIP6 multi-model ensembleParis Climate AgreementMulti-model ensembleQuality regulationsHealth policyEmission changesAssociated with increased mortalityExcess mortalityCMIP6 simulationsClimateParis AgreementEpidemiological dataClimate AgreementDiverse geographical areasCMIP6MortalityGeographical areasA unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state
Chu L, Chen K, Yang Z, Crowley S, Dubrow R. A unified framework for assessing interaction effects among environmental exposures in epidemiologic studies: A case study on temperature, air pollution, and kidney-related conditions in New York state. Environmental Research 2024, 248: 118324. PMID: 38301759, DOI: 10.1016/j.envres.2024.118324.Peer-Reviewed Original ResearchAir pollutionMultiplicative interaction effectsNew York StateEstimated health burdenCase-crossover designEvaluation of effect modificationBi-variate associationsAssess interaction effectsConditional logistic modelMeasures of exposureInteraction effectsEffect modificationPollutionExposure variablesHealth burdenEpidemiological studiesEnvironmental exposuresLog-linear modelLogistic modelInteraction termsQuantitative frameworkAirCase studyExposureAlert systemEffects of air pollution on emergency room visits for mental disorders: risks and effect modification by comorbid physical disorders and personal characteristics
Yoo E, Roberts J, Chen K. Effects of air pollution on emergency room visits for mental disorders: risks and effect modification by comorbid physical disorders and personal characteristics. Environmental Research Health 2024, 2: 025001. DOI: 10.1088/2752-5309/ad1f3f.Peer-Reviewed Original ResearchComorbid physical disordersMental disordersPhysical disordersPersonal characteristicsEffect modificationER visitsNegatively impact mental healthAssociated with ER visitsPotential effect modificationCase-crossover designPotential moderatorsEffects of air pollutionEmergency room visitsEmergency roomMental healthRespiratory diseaseDisordersLevels of air pollutionStratified analysisRoom visitsEffects of daily changesAir pollutionDemographic characteristicsVisitsPrimary diagnosisComprehensive evaluation framework for intervention on health effects of ambient temperature
Wang J, Wang P, Liu B, Kinney P, Huang L, Chen K. Comprehensive evaluation framework for intervention on health effects of ambient temperature. Eco-Environment & Health 2024, 3: 154-164. PMID: 38646097, PMCID: PMC11031729, DOI: 10.1016/j.eehl.2024.01.004.Peer-Reviewed Original ResearchIntervention studiesHealth effectsStudy designEffectiveness of intervention studiesHealth effects of climate changeEvaluation study designIntervention effectsIntervention recommendationsEffective interventionsComprehensive evaluation frameworkEvaluation frameworkHealthInterventionCategories of indicatorsClimate changeEffects of climate changeScoresEffect of ambient temperature
2023
Integrating Augmented In Situ Measurements and a Spatiotemporal Machine Learning Model To Back Extrapolate Historical Particulate Matter Pollution over the United Kingdom: 1980–2019
Liu R, Ma Z, Gasparrini A, de la Cruz A, Bi J, Chen K. Integrating Augmented In Situ Measurements and a Spatiotemporal Machine Learning Model To Back Extrapolate Historical Particulate Matter Pollution over the United Kingdom: 1980–2019. Environmental Science And Technology 2023, 57: 21605-21615. PMID: 38085698, DOI: 10.1021/acs.est.3c05424.Peer-Reviewed Original ResearchAssociation of flooding exposure with cause-specific mortality in North Carolina, United States
Ban J, Sutton C, Ma Y, Lin C, Chen K. Association of flooding exposure with cause-specific mortality in North Carolina, United States. Nature Water 2023, 1: 1027-1034. DOI: 10.1038/s44221-023-00167-5.Peer-Reviewed Original ResearchCause-specific mortalityRelative riskAssociated with mortality riskAssociated with higher relative riskCounty-level estimatesTime series designTwo-stage time-series designHigher relative riskNorth CarolinaOlder adultsSeries designDeaths per yearMortality riskMental disordersUnited StatesAccidental mortalityNon-accidentalRisk increaseTotal deathHealth impactsCardiovascular diseaseCounty levelAssociationMortalityRespiratory diseaseFloods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries
Wang P, Asare E, Pitzer V, Dubrow R, Chen K. Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries. JAMA Pediatrics 2023, 177: 1206-1214. PMID: 37782513, PMCID: PMC10546297, DOI: 10.1001/jamapediatrics.2023.3964.Peer-Reviewed Original ResearchConceptsMiddle-income countriesDiarrhea riskOdds ratioMAIN OUTCOMEMixed-effects logistic regression modelRisk of diarrheaCross-sectional studyHigher odds ratioPrevalence of diarrheaLogistic regression modelsHealth survey programUnexposed childrenEffect modificationChild healthDiarrhea prevalenceSurvey clustersSignificant associationHygiene practicesFourth weekWeeksStrong associationRandom interceptYoung childrenChildrenDiarrheaBesieged on all sides: the future burden of high-temperature-related kidney disease
Chu L, Chen K. Besieged on all sides: the future burden of high-temperature-related kidney disease. The Lancet Regional Health - Western Pacific 2023, 41: 100941. PMID: 37886030, PMCID: PMC10598698, DOI: 10.1016/j.lanwpc.2023.100941.Peer-Reviewed Original ResearchCanadian Wildfire Smoke and Asthma Syndrome Emergency Department Visits in New York City
Chen K, Ma Y, Bell M, Yang W. Canadian Wildfire Smoke and Asthma Syndrome Emergency Department Visits in New York City. JAMA 2023, 330: 1385-1387. PMID: 37733685, PMCID: PMC10514869, DOI: 10.1001/jama.2023.18768.Peer-Reviewed Original ResearchLong-Term Exposure to Fine Particulate Matter and Academic Performance Among Children in North Carolina
Lam P, Zang E, Chen D, Liu R, Chen K. Long-Term Exposure to Fine Particulate Matter and Academic Performance Among Children in North Carolina. JAMA Network Open 2023, 6: e2340928. PMID: 37906198, PMCID: PMC10618843, DOI: 10.1001/jamanetworkopen.2023.40928.Peer-Reviewed Original ResearchRacial/ethnic disparities in PM2.5-attributable cardiovascular mortality burden in the United States
Ma Y, Zang E, Opara I, Lu Y, Krumholz H, Chen K. Racial/ethnic disparities in PM2.5-attributable cardiovascular mortality burden in the United States. Nature Human Behaviour 2023, 7: 2074-2083. PMID: 37653149, PMCID: PMC10901568, DOI: 10.1038/s41562-023-01694-7.Peer-Reviewed Original ResearchConceptsNon-Hispanic White peopleCVD deathMortality burdenNon-Hispanic black peopleCardiovascular disease mortality ratesDisease mortality ratesNon-Hispanic blacksRace/ethnicityMortality rateLong-term exposureWhite peopleEthnic disparitiesHealth benefitsHispanic peopleSignificant differencesBurdenDeathUS countiesEthnic groupsAbsolute disparityAssociationExposureEthnic minoritiesDisparitiesAmbient fine particulate matter (PM2.5) concentrations