2024
Long-term exposure to wildland fire smoke PM2.5 and mortality in the contiguous United States
Ma Y, Zang E, Liu Y, Wei J, Lu Y, Krumholz H, Bell M, Chen K. Long-term exposure to wildland fire smoke PM2.5 and mortality in the contiguous United States. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2403960121. PMID: 39316057, PMCID: PMC11459178, DOI: 10.1073/pnas.2403960121.Peer-Reviewed Original ResearchConceptsWildland firesContiguous United StatesNonaccidental mortalityExposure to ambient fine particlesSmoke PM<sWildland fire smokeMoving average concentrationsAmbient fine particlesLong-term exposureAverage concentrationSmoke PMHealth risksFine particlesFire smokeTemporal confoundingHealth effectsKidney disease mortalityChronic kidney disease mortalityPublic health actionFireMortality rateUnited StatesDisease mortalityHealth actionsMortality outcomesAir pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries
Ma Y, Nobile F, Marb A, Dubrow R, Kinney P, Peters A, Stafoggia M, Breitner S, Chen K. Air pollution changes due to COVID-19 lockdowns and attributable mortality changes in four countries. Environment International 2024, 187: 108668. PMID: 38640613, DOI: 10.1016/j.envint.2024.108668.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionCaliforniaChinaCOVID-19GermanyHumansItalyMortalityNitrogen DioxideParticulate MatterSARS-CoV-2ConceptsMeteorological normalization techniqueAir pollution changesFine particulate matterImprove air qualityEmission control strategiesCentral-southern ItalyPollution changesParticulate matterRegion-specific estimatesAir qualityMeteorological impactsAir pollutionPollutionCOVID-19 lockdownModeling approachAirCaliforniaMortality changesConcentrationJiangsuEmissionTime trendsLocal characteristicsChinaMatterShort-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries
Ma Y, Nobile F, Marb A, Dubrow R, Stafoggia M, Breitner S, Kinney P, Chen K. Short-Term Exposure to Fine Particulate Matter and Nitrogen Dioxide and Mortality in 4 Countries. JAMA Network Open 2024, 7: e2354607. PMID: 38427355, PMCID: PMC10907920, DOI: 10.1001/jamanetworkopen.2023.54607.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsCross-Sectional StudiesEnvironmental ExposureFemaleHumansNitrogen DioxideParticulate MatterConceptsShort-term exposure to air pollutionExposure to air pollutionFine particulate matterCross-sectional studyAir pollutionFixed-effects modelParticulate matterShort-term exposure to PM2.5Short-term exposure to fine particulate matterNO2 concentrationsExposure to fine particulate matterMortality rateNitrogen dioxideSignificant effect modificationDaily PM2.5 concentrationsTime-varying confoundersExposure to PM2.5Health outcomesEstimate associationsMortality dataEffect modificationPM2.5 concentrationsMain OutcomesDay-to-dayCentral-southern Italy
2023
Integrating Augmented In Situ Measurements and a Spatiotemporal Machine Learning Model To Back Extrapolate Historical Particulate Matter Pollution over the United Kingdom: 1980–2019
Liu R, Ma Z, Gasparrini A, de la Cruz A, Bi J, Chen K. Integrating Augmented In Situ Measurements and a Spatiotemporal Machine Learning Model To Back Extrapolate Historical Particulate Matter Pollution over the United Kingdom: 1980–2019. Environmental Science And Technology 2023, 57: 21605-21615. PMID: 38085698, DOI: 10.1021/acs.est.3c05424.Peer-Reviewed Original ResearchAssociations between short-term exposure to PM2.5, NO2 and O3 pollution and kidney-related conditions and the role of temperature-adjustment specification: A case-crossover study in New York state
Chu L, Chen K, Di Q, Crowley S, Dubrow R. Associations between short-term exposure to PM2.5, NO2 and O3 pollution and kidney-related conditions and the role of temperature-adjustment specification: A case-crossover study in New York state. Environmental Pollution 2023, 328: 121629. PMID: 37054868, DOI: 10.1016/j.envpol.2023.121629.Peer-Reviewed Original Research
2021
Ambient carbon monoxide and daily mortality: a global time-series study in 337 cities
Chen K, Breitner S, Wolf K, Stafoggia M, Sera F, Vicedo-Cabrera AM, Guo Y, Tong S, Lavigne E, Matus P, Valdés N, Kan H, Jaakkola JJK, Ryti NRI, Huber V, Scortichini M, Hashizume M, Honda Y, Nunes B, Madureira J, Holobâcă IH, Fratianni S, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Ragettli MS, Guo YL, Chen BY, Li S, Milojevic A, Zanobetti A, Schwartz J, Bell ML, Gasparrini A, Schneider A. Ambient carbon monoxide and daily mortality: a global time-series study in 337 cities. The Lancet Planetary Health 2021, 5: e191-e199. PMID: 33838734, DOI: 10.1016/s2542-5196(21)00026-7.Peer-Reviewed Original ResearchConceptsExposure-response curvesAmbient carbon monoxideTotal mortalityDaily mortalityUK Medical Research CouncilElevated mortality riskLarge epidemiological investigationsPotential publication biasMedical Research CouncilCity-specific associationsMeta-analytical modelsShort-term associationsQuasi-Poisson distributionCurrent air quality guidelinesEpidemiological evidenceMortality riskDaily total mortalityShort-term exposurePublication biasSignificant associationEpidemiological investigationsTime-series studyGreater riskMortalityMortality data
2020
Air pollution reduction and mortality benefit during the COVID-19 outbreak in China
Chen K, Wang M, Huang C, Kinney PL, Anastas PT. Air pollution reduction and mortality benefit during the COVID-19 outbreak in China. The Lancet Planetary Health 2020, 4: e210-e212. PMID: 32411944, PMCID: PMC7220178, DOI: 10.1016/s2542-5196(20)30107-8.Peer-Reviewed Original ResearchHourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany
Chen K, Schneider A, Cyrys J, Wolf K, Meisinger C, Heier M, von Scheidt W, Kuch B, Pitz M, Peters A, Breitner S, Group F. Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany. Environmental Health Perspectives 2020, 128: 017003. PMID: 31939685, PMCID: PMC7015564, DOI: 10.1289/ehp5478.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionEnvironmental ExposureGermanyHumansMyocardial InfarctionParticulate MatterConceptsMyocardial infarctionMI casesTime-stratified case-crossover analysisConditional logistic regressionInterquartile range increaseCase-crossover analysisTwo-pollutant modelsMI registryEpidemiological evidenceDifferent particle metricsCardiovascular diseaseMyocardial infractionSimilar associationLogistic regressionHourly air pollutionParticle metricsEffect estimatesHealth effectsExposure metricsIndependent effectsTransient exposureInfarctionAssociationExposureAerodynamic diameter
2018
Future ozone-related acute excess mortality under climate and population change scenarios in China: A modeling study
Chen K, Fiore AM, Chen R, Jiang L, Jones B, Schneider A, Peters A, Bi J, Kan H, Kinney PL. Future ozone-related acute excess mortality under climate and population change scenarios in China: A modeling study. PLOS Medicine 2018, 15: e1002598. PMID: 29969446, PMCID: PMC6029756, DOI: 10.1371/journal.pmed.1002598.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAge FactorsAgedAir PollutantsCardiovascular DiseasesCause of DeathChildChild, PreschoolChinaClimate ChangeEnvironmental MonitoringFemaleHealth StatusHumansInfantInfant, NewbornInhalation ExposureMaleMiddle AgedModels, TheoreticalOzonePopulation DynamicsPrognosisRespiratory Tract DiseasesRisk AssessmentRisk FactorsSeasonsTime FactorsUrban HealthVehicle EmissionsYoung AdultConceptsGlobal chemistry-climate modelChemistry-climate modelOzone-related mortalityRepresentative Concentration PathwaysEmission scenariosHigh global warmingGlobal warmingClimate changeChange scenariosOzone pollutionClimate Change (IPCC) Representative Concentration PathwaysEmission scenario RCP8.5Emission scenarios RCP4.5Future ozone projectionsStatistical downscaling approachModerate global warmingOzone precursor emissionsFine spatial resolutionSpatial resolutionHigh ambient ozoneOzone projectionsOzone changesOzone observationsScenario RCP8.5Change projectionsTwo-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas
Chen K, Wolf K, Breitner S, Gasparrini A, Stafoggia M, Samoli E, Andersen ZJ, Bero-Bedada G, Bellander T, Hennig F, Jacquemin B, Pekkanen J, Hampel R, Cyrys J, Peters A, Schneider A, Group U. Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas. Environment International 2018, 116: 186-196. PMID: 29689465, DOI: 10.1016/j.envint.2018.04.021.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionCardiovascular DiseasesCitiesEuropeHumansParticulate MatterRetrospective StudiesTemperatureConceptsCardiovascular mortalityAmbient air pollutionShort-term associationsTemperature-mortality associationCity-specific effect estimatesEffect modificationHigh air pollutionMortality riskEpidemiological studiesInfluenza epidemicsMortalityEffect estimatesMortality effectsAir pollutionDaily mortalityAssociationDaysAir pollution levelsDistributed lag