Featured Publications
Cell surface RNAs control neutrophil recruitment
Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan S, Kumar P, Hidalgo A, Wu D, Lu J. Cell surface RNAs control neutrophil recruitment. Cell 2024, 187: 846-860.e17. PMID: 38262409, PMCID: PMC10922858, DOI: 10.1016/j.cell.2023.12.033.Peer-Reviewed Original ResearchConceptsCell surfaceMammalian homologOuter cell surfaceRNA transportGlycan modificationsMammalian cellsSID-1Cellular functionsRecruitment to inflammatory sitesGlycoRNARNAMurine neutrophilsFunctional significanceNeutrophil recruitmentNeutrophil recruitment to inflammatory sitesBiological importanceCellsNeutrophil adhesionReduced neutrophil adhesionHomologyGlycansGenesInflammatory sitesRecruitmentEndothelial cells
2022
N 6-methyladenosine enhances post-transcriptional gene regulation by microRNAs
Kanoria S, Rennie WA, Carmack CS, Lu J, Ding Y. N 6-methyladenosine enhances post-transcriptional gene regulation by microRNAs. Bioinformatics Advances 2022, 2: vbab046. PMID: 35098135, PMCID: PMC8792947, DOI: 10.1093/bioadv/vbab046.Peer-Reviewed Original ResearchPost-transcriptional gene regulationMiRNA-binding sitesGene regulationMiRNA-mediated gene regulationEukaryotic messenger RNAsMiRNA-mediated regulationMiRNA-target bindingRNA-binding proteinMiRNA target sitesPost-transcriptional regulatorsPotential methylation sitesHigh GC contentHigh-throughput dataArgonaute proteinsEvolutionary conservationPrevalent modificationTarget mRNAsGC contentMethylation sitesTarget secondary structureGene expressionRNA structureSecondary structureMessenger RNAFunctional significance