2024
Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench.
Humes I, Shyr C, Dillon M, Liu Z, Peterson J, Jeor CS, Malkes J, Master H, Mapes B, Azuine R, Mack N, Abdelbary B, Gamble-George J, Goldmann E, Cook S, Choupani F, Baskir R, McMaster S, Lunt C, Watson K, Lee M, Schwartz S, Munshi R, Glazer D, Banks E, Philippakis A, Basford M, Roden D, Harris PA. Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench. J Am Med Inform Assoc 2024 PMID: 39135439, DOI: 10.1093/jamia/ocae216.Peer-Reviewed Original Research
2022
Racial and ethnic differences in the association of social cohesion and social capital with HIV testing
Ransome Y, Hayashi K, Gamble-George J, Dean L, Villalonga-Olives E. Racial and ethnic differences in the association of social cohesion and social capital with HIV testing. SSM - Population Health 2022, 21: 101327. PMID: 36618543, PMCID: PMC9811247, DOI: 10.1016/j.ssmph.2022.101327.Peer-Reviewed Original ResearchPublic Engagement with Biotechnology Inside and Outside the Classroom: Community-Focused Approaches
Jimenez J, Gamble-George J, Danies G, Hamm R, Porras A. Public Engagement with Biotechnology Inside and Outside the Classroom: Community-Focused Approaches. GEN Biotechnology 2022, 1: 346-354. PMID: 36032190, PMCID: PMC9407021, DOI: 10.1089/genbio.2022.0024.Peer-Reviewed Original ResearchAcceptance of biotechnologyCommunity-focused approachCommunity participationPublic engagementGlobal communityBiotechnology innovationPublic perceptionPublic concernSocioeconomic conditionsAdoption processPresent opportunitiesSuccessful implementationEngagementCommunityVast benefitsOpportunitiesOppositionInitiativesParticipationPublicPerspectiveEducationInnovationHealthCrucial factorHIV-Related Stigma Research as a Priority at the National Institutes of Health.
Greenwood GL, Wilson A, Bansal GP, Barnhart C, Barr E, Berzon R, Boyce CA, Elwood W, Gamble-George J, Glenshaw M, Henry R, Iida H, Jenkins RA, Lee S, Malekzadeh A, Morris K, Perrin P, Rice E, Sufian M, Weatherspoon D, Whitaker M, Williams M, Zwerski S, Gaist P. HIV-Related Stigma Research as a Priority at the National Institutes of Health. AIDS Behav 2022, 26: 5-26. PMID: 33886010, DOI: 10.1007/s10461-021-03260-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2021
Alcohol Use Cravings as a Mediator Between Associated Risk Factors on Increased Alcohol Use among Youth Adults in New York During the COVID-19 Pandemic
Opara I, Malik S, Lardier D, Gamble-George J, Kelly R, Okafor C, Greene R, Parisi D. Alcohol Use Cravings as a Mediator Between Associated Risk Factors on Increased Alcohol Use among Youth Adults in New York During the COVID-19 Pandemic. Alcoholism Treatment Quarterly 2021, 39: 415-429. PMID: 34898835, PMCID: PMC8664084, DOI: 10.1080/07347324.2021.1950091.Peer-Reviewed Original ResearchCOVID-19 diagnosisAlcohol useCOVID-19 pandemicAssociated risk factorsYears of ageMental health symptomsYoung adult populationPublic health professionalsAlcohol use preventionResidents 18Mean ageRisk factorsSleep disturbancesHealth professionalsTreatment resourcesHealth symptomsAdult populationUse preventionSpecific psychological factorsCOVID-19 eraSocial isolationCravingMediatorsDiagnosisTotal sampleIn Parkinson's patient-derived dopamine neurons, the triplication of α-synuclein locus induces distinctive firing pattern by impeding D2 receptor autoinhibition.
Lin M, Mackie PM, Shaerzadeh F, Gamble-George J, Miller DR, Martyniuk CJ, Khoshbouei H. In Parkinson's patient-derived dopamine neurons, the triplication of α-synuclein locus induces distinctive firing pattern by impeding D2 receptor autoinhibition. Acta Neuropathol Commun 2021, 9: 107. PMID: 34099060, DOI: 10.1186/s40478-021-01203-9.Peer-Reviewed Original ResearchMaternal Morbidity and Mortality: Are We Getting to the "Heart" of the Matter?
Varagic J, Desvigne-Nickens P, Gamble-George J, Hollier L, Maric-Bilkan C, Mitchell M, Pemberton VL, Redmond N. Maternal Morbidity and Mortality: Are We Getting to the "Heart" of the Matter? J Womens Health (Larchmt) 2021, 30: 178-186. PMID: 33259740, DOI: 10.1089/jwh.2020.8852.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Letter by Gamble-George et al Regarding Article, "Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center".
Gamble-George JC, Redmond N, Boyce CA. Letter by Gamble-George et al Regarding Article, "Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center". Circ Heart Fail 2020, 13: e007171. PMID: 32498622, DOI: 10.1161/CIRCHEARTFAILURE.120.007171.Commentaries, Editorials and LettersImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research.
Gamble-George JC, Longenecker CT, Webel AR, Au DH, Brown AF, Bosworth H, Crothers K, Cunningham WE, Fiscella KA, Hamilton AB, Helfrich CD, Ladapo JA, Luque A, Tobin JN, Wyatt GE, Implementation Research to Develop Interventions for People Living with HIV (PRECluDE) Consortium. ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research. Prog Cardiovasc Dis 2020, 63: 79-91. PMID: 32199901, DOI: 10.1016/j.pcad.2020.03.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
HIV-1 Tat regulation of dopamine transmission and microglial reactivity is brain region specific.
Miller DR, Shaerzadeh F, Phan L, Sharif N, Gamble-George J, McLaughlin JP, Streit WJ, Khoshbouei H. HIV-1 Tat regulation of dopamine transmission and microglial reactivity is brain region specific. Glia 2018, 66: 1915-1928. PMID: 29733459, DOI: 10.1002/glia.23447.Peer-Reviewed Original Research
2017
HIV, Tat and dopamine transmission.
Gaskill PJ, Miller DR, Gamble-George J, Yano H, Khoshbouei H. HIV, Tat and dopamine transmission. Neurobiol Dis 2017, 105: 51-73. PMID: 28457951, DOI: 10.1016/j.nbd.2017.04.015.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2016
Cyclooxygenase-2 inhibition reduces stress-induced affective pathology.
Gamble-George JC, Baldi R, Halladay L, Kocharian A, Hartley N, Silva CG, Roberts H, Haymer A, Marnett LJ, Holmes A, Patel S. Cyclooxygenase-2 inhibition reduces stress-induced affective pathology. Elife 2016, 5 PMID: 27162170, DOI: 10.7554/eLife.14137.Peer-Reviewed Original Research
2014
Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.
Bluett RJ, Gamble-George JC, Hermanson DJ, Hartley ND, Marnett LJ, Patel S. Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. Transl Psychiatry 2014, 4: e408. PMID: 25004388, DOI: 10.1038/tp.2014.53.Peer-Reviewed Original ResearchSubstrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation.
Hermanson DJ, Gamble-George JC, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation. Trends Pharmacol Sci 2014, 35: 358-67. PMID: 24845457, DOI: 10.1016/j.tips.2014.04.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMultiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses.
Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S. Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron 2014, 81: 1111-1125. PMID: 24607231, DOI: 10.1016/j.neuron.2014.01.012.Peer-Reviewed Original ResearchChronic Methamphetamine Increases Alpha-Synuclein Protein Levels in the Striatum and Hippocampus but not in the Cortex of Juvenile Mice.
Butler B, Gamble-George J, Prins P, North A, Clarke JT, Khoshbouei H. Chronic Methamphetamine Increases Alpha-Synuclein Protein Levels in the Striatum and Hippocampus but not in the Cortex of Juvenile Mice. J Addict Prev 2014, 2 PMID: 25621291.Peer-Reviewed Original Research
2013
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation.
Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. Nat Neurosci 2013, 16: 1291-8. PMID: 23912944, DOI: 10.1038/nn.3480.Peer-Reviewed Original ResearchDissociable effects of CB1 receptor blockade on anxiety-like and consummatory behaviors in the novelty-induced hypophagia test in mice.
Gamble-George JC, Conger JR, Hartley ND, Gupta P, Sumislawski JJ, Patel S. Dissociable effects of CB1 receptor blockade on anxiety-like and consummatory behaviors in the novelty-induced hypophagia test in mice. Psychopharmacology (Berl) 2013, 228: 401-9. PMID: 23483200, DOI: 10.1007/s00213-013-3042-8.Peer-Reviewed Original ResearchConvergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.
Gunduz-Cinar O, MacPherson KP, Cinar R, Gamble-George J, Sugden K, Williams B, Godlewski G, Ramikie TS, Gorka AX, Alapafuja SO, Nikas SP, Makriyannis A, Poulton R, Patel S, Hariri AR, Caspi A, Moffitt TE, Kunos G, Holmes A. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. Mol Psychiatry 2013, 18: 813-23. PMID: 22688188, DOI: 10.1038/mp.2012.72.Peer-Reviewed Original ResearchChronic methamphetamine exposure produces a delayed, long-lasting memory deficit.
North A, Swant J, Salvatore MF, Gamble-George J, Prins P, Butler B, Mittal MK, Heltsley R, Clark JT, Khoshbouei H. Chronic methamphetamine exposure produces a delayed, long-lasting memory deficit. Synapse 2013, 67: 245-57. PMID: 23280858, DOI: 10.1002/syn.21635.Peer-Reviewed Original Research