Characteristics of Patients With Initial Clostridioides difficile Infection (CDI) That Are Associated With Increased Risk of Multiple CDI Recurrences
Guh A, Li R, Korhonen L, Winston L, Parker E, Czaja C, Johnston H, Basiliere E, Meek J, Olson D, Fridkin S, Wilson L, Perlmutter R, Holzbauer S, D’Heilly P, Phipps E, Flores K, Dumyati G, Pierce R, Ocampo V, Wilson C, Watkins J, Gerding D, McDonald L. Characteristics of Patients With Initial Clostridioides difficile Infection (CDI) That Are Associated With Increased Risk of Multiple CDI Recurrences. Open Forum Infectious Diseases 2024, 11: ofae127. PMID: 38577028, PMCID: PMC10993058, DOI: 10.1093/ofid/ofae127.Peer-Reviewed Original ResearchRecurrent Clostridioides difficile infectionClostridioides difficile infectionInitial CDINitrofurantoin useMultiple recurrent Clostridioides difficile infectionsPositive testPositive C. difficile testMultiple CDI recurrencesMultivariate logistic regression analysisPrevent further recurrenceAssociated with increased riskIntervention study designProportion of patientsTime of presentationCharacteristics of patientsLogistic regression analysisClinical decision makingCDI recurrenceChronic hemodialysisAdjunctive therapyIncreased riskMultivariate analysisStudy designPatientsClinical setting