2023
684. Characteristics of Patients with Initial Clostridioides difficile Infection (CDI) That Are Associated With Increased Risk of Multiple CDI Recurrences
Guh A, Li R, Korhonen L, Winston L, Parker E, Czaja C, Johnston H, Basiliere E, Meek J, Olson D, Fridkin S, Wilson L, Perlmutter R, Holzbauer S, D’Heilly P, Phipps E, Flores K, Dumyati G, Pierce R, Ocampo V, Wilson C, Watkins J, Gerding D, McDonald L. 684. Characteristics of Patients with Initial Clostridioides difficile Infection (CDI) That Are Associated With Increased Risk of Multiple CDI Recurrences. Open Forum Infectious Diseases 2023, 10: ofad500.746. PMCID: PMC10677783, DOI: 10.1093/ofid/ofad500.746.Peer-Reviewed Original ResearchEmerging Infections ProgramClostridioides difficile infectionInitial Clostridioides difficile infectionInitial CDICharacteristics of patientsRecurrent CDIPositive testNitrofurantoin useRecent hospitalizationDifficile infectionPrevention's Emerging Infections ProgramRecurrent Clostridioides difficile infectionMultivariable logistic regression modelMultiple recurrent CDIPrevious positive testTime of presentationFull chart reviewGrant/research supportPrior positive testLogistic regression modelsRace/ethnicityChronic hemodialysisAdjunctive therapyChart reviewConclusions Patients
2022
2314. Hospitalizations and Antibiotic Use in the Year Prior to an Incident C. difficile Infection for Medicare Beneficiaries in Four States, 2016–2018
Hatfield K, Baggs J, Reddy S, Aranmolate R, Meek J, Fridkin S, Szydlowski J, Hatwar T, Dumyati G, Watkins J, Wilson C, McDonald L, Jernigan J, Guh A. 2314. Hospitalizations and Antibiotic Use in the Year Prior to an Incident C. difficile Infection for Medicare Beneficiaries in Four States, 2016–2018. Open Forum Infectious Diseases 2022, 9: ofac492.146. PMCID: PMC9752406, DOI: 10.1093/ofid/ofac492.146.Peer-Reviewed Original ResearchOutpatient antibiotic useEmerging Infections ProgramClostridioides difficile infectionAntibiotic useCDI casesDifficile infectionRisk factorsMedicare beneficiariesPrevention's Emerging Infections ProgramAntibiotic classesPrior yearAntibiotic stewardship effortsC. difficile infectionMultiple risk factorsInpatient hospitalization dataMedicare Provider AnalysisTiming of hospitalizationGrant/research supportDifferent antibiotic classesAntibiotic prescriptionsCase patientsMedian lengthOutpatient antibioticsCDI surveillanceCDI diagnosis
2018
492. Long-Term Outcomes of Clostridium difficile Infection Among Medicare Beneficiaries
Hatfield K, Baggs J, Winston L, Parker E, Martin B, Meek J, Olson D, Farley M, Revis A, Holzbauer S, Bye M, Wilson L, Perlmutter R, Phipps E, Pierce R, Ocampo V, Kainer M, Smith M, McDonald L, Jernigan J, Guh A. 492. Long-Term Outcomes of Clostridium difficile Infection Among Medicare Beneficiaries. Open Forum Infectious Diseases 2018, 5: s182-s182. PMCID: PMC6253260, DOI: 10.1093/ofid/ofy210.501.Peer-Reviewed Original ResearchClostridium difficile infectionEmerging Infections ProgramDifficile infectionInclusion criteriaCommon healthcare-associated infectionsPrevention's Emerging Infections ProgramMultivariable logistic regression modelICD-9-CM codesOlder adultsDifficile stool testMedicaid Services beneficiariesNumber of hospitalizationsHealthcare-associated infectionsSkilled nursing facilitiesLong-term riskLogistic regression modelsSame catchment areaExcess morbidityHospitalization statusStool testPoor outcomeTerm outcomesAdjusted oddsCDI casesChronic conditions
2011
Association Between Use of Statins and Mortality Among Patients Hospitalized With Laboratory-Confirmed Influenza Virus Infections: A Multistate Study
Vandermeer M, Thomas A, Kamimoto L, Reingold A, Gershman K, Meek J, Farley M, Ryan P, Lynfield R, Baumbach J, Schaffner W, Bennett N, Zansky S. Association Between Use of Statins and Mortality Among Patients Hospitalized With Laboratory-Confirmed Influenza Virus Infections: A Multistate Study. The Journal Of Infectious Diseases 2011, 205: 13-19. PMID: 22170954, DOI: 10.1093/infdis/jir695.Peer-Reviewed Original ResearchConceptsEmerging Infections ProgramLaboratory-confirmed influenzaInfluenza virus infectionVirus infectionPrevention's Emerging Infections ProgramMultivariable logistic regression modelInfluenza-related deathsChronic lung diseaseUse of statinsAdministration of statinsRisk of mortalityLogistic regression modelsProtective oddsHospitalized adultsInfluenza testsInfluenza vaccinationStatin useInfluenza seasonRenal diseaseAntiviral administrationImmunomodulatory effectsLung diseaseActive surveillanceInfections ProgramStatins