2022
2314. Hospitalizations and Antibiotic Use in the Year Prior to an Incident C. difficile Infection for Medicare Beneficiaries in Four States, 2016–2018
Hatfield K, Baggs J, Reddy S, Aranmolate R, Meek J, Fridkin S, Szydlowski J, Hatwar T, Dumyati G, Watkins J, Wilson C, McDonald L, Jernigan J, Guh A. 2314. Hospitalizations and Antibiotic Use in the Year Prior to an Incident C. difficile Infection for Medicare Beneficiaries in Four States, 2016–2018. Open Forum Infectious Diseases 2022, 9: ofac492.146. PMCID: PMC9752406, DOI: 10.1093/ofid/ofac492.146.Peer-Reviewed Original ResearchOutpatient antibiotic useEmerging Infections ProgramClostridioides difficile infectionAntibiotic useCDI casesDifficile infectionRisk factorsMedicare beneficiariesPrevention's Emerging Infections ProgramAntibiotic classesPrior yearAntibiotic stewardship effortsC. difficile infectionMultiple risk factorsInpatient hospitalization dataMedicare Provider AnalysisTiming of hospitalizationGrant/research supportDifferent antibiotic classesAntibiotic prescriptionsCase patientsMedian lengthOutpatient antibioticsCDI surveillanceCDI diagnosis
2016
Burden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes
Hunter J, Mu Y, Dumyati G, Farley M, Winston L, Johnston H, Meek J, Perlmutter R, Holzbauer S, Beldavs Z, Phipps E, Dunn J, Cohen J, Avillan J, Stone N, Gerding D, McDonald L, Lessa F. Burden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes. Open Forum Infectious Diseases 2016, 3: ofv196. PMID: 26798767, PMCID: PMC4719744, DOI: 10.1093/ofid/ofv196.Peer-Reviewed Original ResearchClostridium difficile infectionDifficile infectionPatient outcomesPopulation-based surveillanceAcute care settingAppropriate antibiotic useEstimates of incidenceMedian ageSubstantial morbidityPositive stoolsMedical recordsRisk factorsAdvanced ageAntibiotic useInfection preventionAntibiotic exposureHome residentsNational incidenceCare settingsPositive specimenNational estimatesIncidenceSpecimen collectionAgeStool
2015
Association Between Outpatient Antibiotic Prescribing Practices and Community-Associated Clostridium difficile Infection
Dantes R, Mu Y, Hicks L, Cohen J, Bamberg W, Beldavs Z, Dumyati G, Farley M, Holzbauer S, Meek J, Phipps E, Wilson L, Winston L, McDonald L, Lessa F. Association Between Outpatient Antibiotic Prescribing Practices and Community-Associated Clostridium difficile Infection. Open Forum Infectious Diseases 2015, 2: ofv113. PMID: 26509182, PMCID: PMC4551478, DOI: 10.1093/ofid/ofv113.Peer-Reviewed Original ResearchClostridium difficile infectionCA-CDI ratesOutpatient antibiotic prescribingAntibiotic useAntibiotic prescribingDifficile infectionCommunity-Associated Clostridium difficile InfectionIMS Health Xponent databaseOutpatient antibiotic prescribing practicesAmoxicillin/clavulanic acidCA-CDI casesSurveillance area residentAntibiotic prescribing ratesAntibiotic prescription ratesAntibiotic prescribing practicesCourse of antibioticsOral antibiotic prescriptionsLaboratory-based surveillance dataOutpatient antibiotic useCDI preventionAntibiotic prescriptionsPrescribing ratesHospital admissionPrescription ratesPrescribing practices
2014
Vital signs: improving antibiotic use among hospitalized patients.
Fridkin S, Baggs J, Fagan R, Magill S, Pollack LA, Malpiedi P, Slayton R, Khader K, Rubin MA, Jones M, Samore MH, Dumyati G, Dodds-Ashley E, Meek J, Yousey-Hindes K, Jernigan J, Shehab N, Herrera R, McDonald L, Schneider A, Srinivasan A. Vital signs: improving antibiotic use among hospitalized patients. MMWR Morbidity And Mortality Weekly Report 2014, 63: 194-200. PMID: 24598596, PMCID: PMC4584728.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionAntibiotic prescribingAntibiotic useIncidence of CDIInpatient antibiotic useDays of therapyNational administrative databaseBroad-spectrum antibioticsHealth care providersAntibiotic-resistant infectionsHospitalized patientsSurgical wardsDifficile infectionImproved prescribingAdministrative databasesAntibiotic exposureIncorrect prescribingPrescribingPatientsHospitalPatient recordsPatient safetyU.S. hospitalsAntibiotic resistanceAntibiotics