2020
Inflection Point
Krumholz HM. Inflection Point. Circulation Cardiovascular Quality And Outcomes 2020, 13: e007615-e007615. PMID: 33200951, PMCID: PMC7742208, DOI: 10.1161/circoutcomes.120.007615.Peer-Reviewed Original ResearchEvaluation of Case Volumes of a Heart Transplant Program and Short-term Outcomes After Changes in the United Network for Organ Sharing Donor Heart Allocation System
Mori M, Wilson L, Ali A, Ahmad T, Anwer M, Jacoby D, Geirsson A, Krumholz HM. Evaluation of Case Volumes of a Heart Transplant Program and Short-term Outcomes After Changes in the United Network for Organ Sharing Donor Heart Allocation System. JAMA Network Open 2020, 3: e2017513. PMID: 32945877, PMCID: PMC7501535, DOI: 10.1001/jamanetworkopen.2020.17513.Peer-Reviewed Original ResearchConceptsYale-New Haven HospitalHeart transplant programShort-term outcomesHeart transplantHeart transplant volumeNew Haven HospitalDonor heartsPatient selectionRecipient selectionTransplant programsTransplant volumeWaiting listCase volumeDonor heart allocation systemPre-post cohort studyConservative patient selectionUnused donor heartsHeart allocation systemHigher median numberCirculatory assist devicesCohort studyPatient characteristicsMore patientsSingle centerCenter volume
2018
Effects of the Hospital Readmissions Reduction Program
Khera R, Krumholz HM. Effects of the Hospital Readmissions Reduction Program. Circulation Cardiovascular Quality And Outcomes 2018, 11: e005083. PMID: 30562071, DOI: 10.1161/circoutcomes.118.005083.Peer-Reviewed Original ResearchThe 21st Century Cures Act and electronic health records one year later: will patients see the benefits?
Lye CT, Forman HP, Daniel JG, Krumholz HM. The 21st Century Cures Act and electronic health records one year later: will patients see the benefits? Journal Of The American Medical Informatics Association 2018, 25: 1218-1220. PMID: 30184156, PMCID: PMC7646899, DOI: 10.1093/jamia/ocy065.Peer-Reviewed Original ResearchConceptsElectronic health recordsHealth recordsHealth information technologyInformation exchange networkHealth information exchangeData sharingHealth information exchange networkInformation technologyCentury Cures ActInformation exchangeInteroperabilityHealth dataCures ActImplementationAccessResearch initiativesRequirementsExchange networksSharingCertification requirementsNetworkTechnologyPotential benefitsRulesImpact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study
Khera R, Lu Y, Lu J, Saxena A, Nasir K, Jiang L, Krumholz HM. Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study. The BMJ 2018, 362: k2357. PMID: 29997129, PMCID: PMC6039831, DOI: 10.1136/bmj.k2357.Peer-Reviewed Original ResearchConceptsACC/AHA guidelinesDiagnosis of hypertensionAge groupsHypertension guidelinesAHA guidelinesTreatment patternsCurrent guidelinesACC/AHA hypertension guidelinesHeart Association hypertension guidelinesCurrent treatment patternsIntensification of treatmentPrevalence of hypertensionNutrition Examination SurveyYears age groupUS National HealthYear old adultsSame age groupRetirement Longitudinal StudyAntihypertensive treatmentExamination SurveyNational HealthHypertensionAmerican CollegeChina HealthOlder adultsRising Mortality in Patients With Heart Failure in the United States Facts Versus Fiction
Khera R, Dharmarajan K, Krumholz HM. Rising Mortality in Patients With Heart Failure in the United States Facts Versus Fiction. JACC Heart Failure 2018, 6: 610-612. PMID: 29914774, DOI: 10.1016/j.jchf.2018.02.011.Peer-Reviewed Original Research
2017
2017 Roadmap for Innovation—ACC Health Policy Statement on Healthcare Transformation in the Era of Digital Health, Big Data, and Precision Health A Report of the American College of Cardiology Task Force on Health Policy Statements and Systems of Care
Bhavnani SP, Parakh K, Atreja A, Druz R, Graham GN, Hayek SS, Krumholz HM, Maddox TM, Majmudar MD, Rumsfeld JS, Shah BR. 2017 Roadmap for Innovation—ACC Health Policy Statement on Healthcare Transformation in the Era of Digital Health, Big Data, and Precision Health A Report of the American College of Cardiology Task Force on Health Policy Statements and Systems of Care. Journal Of The American College Of Cardiology 2017, 70: 2696-2718. PMID: 29169478, DOI: 10.1016/j.jacc.2017.10.018.Peer-Reviewed Original Research
2015
Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system
Jiang L, Krumholz HM, Li X, Li J, Hu S. Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system. The Lancet 2015, 386: 1493-1505. PMID: 26466053, PMCID: PMC5323019, DOI: 10.1016/s0140-6736(15)00343-8.Peer-Reviewed Original Research
2014
Impact of Drug Policy on Regional Trends in Ezetimibe Use
Lu L, Krumholz HM, Tu JV, Ross JS, Ko DT, Jackevicius CA. Impact of Drug Policy on Regional Trends in Ezetimibe Use. Circulation Cardiovascular Quality And Outcomes 2014, 7: 589-596. PMID: 24895451, PMCID: PMC4222175, DOI: 10.1161/circoutcomes.114.001023.Peer-Reviewed Original Research
2011
ACCF/AHA 2011 Health Policy Statement on Therapeutic Interchange and Substitution A Report of the American College of Cardiology Foundation Clinical Quality Committee
Holmes D, Becker J, Granger C, Limacher M, Page R, Sila C, Drozda J, Cacchione J, Erb B, Harrington R, Kennett J, Krumholz H, Masoudi F, Peterson E, Poppas A, Sahn D, Sanz M, Shahian D, Windle J, Wyman J. ACCF/AHA 2011 Health Policy Statement on Therapeutic Interchange and Substitution A Report of the American College of Cardiology Foundation Clinical Quality Committee. Journal Of The American College Of Cardiology 2011, 58: 1287-1307. PMID: 21849242, DOI: 10.1016/j.jacc.2011.06.001.Peer-Reviewed Original Research
2010
ACCF/AHA New Insights Into the Methodology of Performance Measurement
MEERS W, Spertus J, Bonow R, Chan P, Diamond G, Drozda J, Kaul S, Krumholz H, Masoudi F, Normand S, Peterson E, Radford M, Rumsfeld J. ACCF/AHA New Insights Into the Methodology of Performance Measurement. Circulation 2010, 122: 2091-2106. PMID: 21060078, DOI: 10.1161/cir.0b013e3181f7d78c.Peer-Reviewed Original ResearchACCF/AHA New Insights Into the Methodology of Performance Measurement
Foundation A, Measures A, Spertus J, Bonow R, Chan P, Diamond G, Drozda J, Kaul S, Krumholz H, Masoudi F, Normand S, Peterson E, Radford M, Rumsfeld J. ACCF/AHA New Insights Into the Methodology of Performance Measurement. Journal Of The American College Of Cardiology 2010, 56: 1767-1782. PMID: 21070935, DOI: 10.1016/j.jacc.2010.09.009.Peer-Reviewed Original Research
2009
Patterns of Hospital Performance in Acute Myocardial Infarction and Heart Failure 30-Day Mortality and Readmission
Krumholz HM, Merrill AR, Schone EM, Schreiner GC, Chen J, Bradley EH, Wang Y, Wang Y, Lin Z, Straube BM, Rapp MT, Normand SL, Drye EE. Patterns of Hospital Performance in Acute Myocardial Infarction and Heart Failure 30-Day Mortality and Readmission. Circulation Cardiovascular Quality And Outcomes 2009, 2: 407-413. PMID: 20031870, DOI: 10.1161/circoutcomes.109.883256.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHeart failureReadmission ratesMyocardial infarctionMortality rateRisk-standardized mortality ratesAge 65 yearsRisk-standardized mortalityHospital referral regionsHospital structural characteristicsType of hospitalHospital performancePrimary diagnosisHospital characteristicsReferral regionsMedicare feeMortalityMedicaid ServicesInfarctionHospitalGeographic differencesReadmissionFailureDiagnosis
2008
Standards for Measures Used for Public Reporting of Efficiency in Health Care
Krumholz HM, Keenan PS, Brush JE, Bufalino VJ, Chernew ME, Epstein AJ, Heidenreich PA, Ho V, Masoudi FA, Matchar DB, Normand SL, Rumsfeld JS, Schuur JD, Smith SC, Spertus JA, Walsh MN. Standards for Measures Used for Public Reporting of Efficiency in Health Care. Circulation 2008, 118: 1885-1893. PMID: 18838567, DOI: 10.1161/circulationaha.108.190500.Peer-Reviewed Original ResearchStandards for Measures Used for Public Reporting of Efficiency in Health Care A Scientific Statement From the American Heart Association Interdisciplinary Council on Quality of Care and Outcomes Research and the American College of Cardiology Foundation
Krumholz HM, Keenan PS, Brush JE, Bufalino VJ, Chernew ME, Epstein AJ, Heidenreich PA, Ho V, Masoudi FA, Matchar DB, Normand SL, Rumsfeld JS, Schuur JD, Smith SC, Spertus JA, Walsh MN. Standards for Measures Used for Public Reporting of Efficiency in Health Care A Scientific Statement From the American Heart Association Interdisciplinary Council on Quality of Care and Outcomes Research and the American College of Cardiology Foundation. Journal Of The American College Of Cardiology 2008, 52: 1518-1526. PMID: 19017522, DOI: 10.1016/j.jacc.2008.09.004.Peer-Reviewed Original ResearchOutcomes Research
Krumholz HM. Outcomes Research. Circulation 2008, 118: 309-318. PMID: 18625906, DOI: 10.1161/circulationaha.107.690917.Peer-Reviewed Original Research
2007
Development of Systems of Care for ST-Elevation Myocardial Infarction Patients
Nallamothu BK, Krumholz HM, Ko DT, LaBresh KA, Rathore S, Roe MT, Schwamm L. Development of Systems of Care for ST-Elevation Myocardial Infarction Patients. Circulation 2007, 116: e68-72. PMID: 17538036, DOI: 10.1161/circulationaha.107.184052.Peer-Reviewed Original Research
2006
Regionalization of ST-Segment Elevation Acute Coronary Syndromes Care Putting a National Policy in Proper Perspective
Rathore SS, Epstein AJ, Nallamothu BK, Krumholz HM. Regionalization of ST-Segment Elevation Acute Coronary Syndromes Care Putting a National Policy in Proper Perspective. Journal Of The American College Of Cardiology 2006, 47: 1346-1349. PMID: 16580519, PMCID: PMC2789345, DOI: 10.1016/j.jacc.2005.11.053.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCISTEMI patientsFibrinolytic therapyPCI hospitalsST-segment elevation myocardial infarction (STEMI) careAcute coronary syndrome careHigh-volume PCI hospitalsHigh-risk STEMI patientsElevation Myocardial Infarction CareHigh-volume hospitalsLow-volume hospitalsPercutaneous coronary interventionMyocardial infarction careCardiac care facilitiesHealth care resourcesHealth care systemInitial hospitalPCI patientsCoronary interventionU.S. health care systemAverage patientSingle deathCare facilitiesPatientsIsolation of Health Services Research from Practice and Policy: The Example of Chronic Heart Failure Management
Seow H, Phillips CO, Rich MW, Spertus JA, Krumholz HM, Lynn J. Isolation of Health Services Research from Practice and Policy: The Example of Chronic Heart Failure Management. Journal Of The American Geriatrics Society 2006, 54: 535-540. PMID: 16551325, DOI: 10.1111/j.1532-5415.2005.00638.x.Peer-Reviewed Original ResearchConceptsChronic heart failureHealth services researchCHF managementChronic heart failure managementHeart failure managementImproved patient outcomesServices researchHealth services researchersHeart failurePatient outcomesClinical carePatient benefitRoutine practiceFailure managementDisease managementHealthcare deliveryServices researchersE-mail surveyTrialsU.S. studiesLiterature reviewManagementCare
2002
Task Force #2—the cost of prevention: can we afford it? Can we afford not to do it?
Krumholz HM, Weintraub WS, Bradford WD, Heidenreich PA, Mark DB, Paltiel AD. Task Force #2—the cost of prevention: can we afford it? Can we afford not to do it? Journal Of The American College Of Cardiology 2002, 40: 603-615. PMID: 12204490, DOI: 10.1016/s0735-1097(02)02083-1.Peer-Reviewed Original Research