2017
Nonclinical Factors Affecting Shared Decision Making—Reply
Spatz ES, Moulton BW, Krumholz HM. Nonclinical Factors Affecting Shared Decision Making—Reply. JAMA 2017, 318: 391-392. PMID: 28742902, DOI: 10.1001/jama.2017.7865.Peer-Reviewed Original ResearchPrime Time for Shared Decision Making
Spatz ES, Krumholz HM, Moulton BW. Prime Time for Shared Decision Making. JAMA 2017, 317: 1309-1310. PMID: 28384834, DOI: 10.1001/jama.2017.0616.Peer-Reviewed Original Research
2016
The New Era of Informed Consent: Getting to a Reasonable-Patient Standard Through Shared Decision Making
Spatz ES, Krumholz HM, Moulton BW. The New Era of Informed Consent: Getting to a Reasonable-Patient Standard Through Shared Decision Making. JAMA 2016, 315: 2063. PMID: 27099970, PMCID: PMC5459384, DOI: 10.1001/jama.2016.3070.Peer-Reviewed Original Research
2014
Patient and Caregiver Viewpoints
Mann MK, Krumholz HM. Patient and Caregiver Viewpoints. Circulation Cardiovascular Quality And Outcomes 2014, 7: 634. PMID: 25097211, DOI: 10.1161/circoutcomes.114.001248.Peer-Reviewed Original ResearchClinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012
Downing NS, Aminawung JA, Shah ND, Krumholz HM, Ross JS. Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012. JAMA 2014, 311: 368-377. PMID: 24449315, PMCID: PMC4144867, DOI: 10.1001/jama.2013.282034.Peer-Reviewed Original ResearchConceptsPivotal efficacy trialsNovel therapeutic agentsClinical trial evidencePivotal trialsEfficacy trialsTherapeutic agentsEnd pointTrial evidenceMedian numberAvailable FDA documentsSingle pivotal trialTrial end pointsSurrogate end pointsNumber of patientsLength of treatmentCross-sectional analysisPrimary outcomeClinical outcomesTrial completion ratesClinical benefitPlacebo comparatorSurrogate outcomesMAIN OUTCOMEDrug AdministrationUS Food
2013
Decision-making preferences among patients with an acute myocardial infarction.
Krumholz HM, Barreto-Filho JA, Jones PG, Li Y, Spertus JA. Decision-making preferences among patients with an acute myocardial infarction. JAMA Internal Medicine 2013, 173: 1252-7. PMID: 23712775, PMCID: PMC4409122, DOI: 10.1001/jamainternmed.2013.6057.Peer-Reviewed Original ResearchUshering in a New Era of Open Science Through Data Sharing: The Wall Must Come Down
Ross JS, Krumholz HM. Ushering in a New Era of Open Science Through Data Sharing: The Wall Must Come Down. JAMA 2013, 309: 1355-1356. PMID: 23508736, DOI: 10.1001/jama.2013.1299.Commentaries, Editorials and Letters
2012
Decision Making in Advanced Heart Failure
Allen LA, Stevenson LW, Grady KL, Goldstein NE, Matlock DD, Arnold RM, Cook NR, Felker GM, Francis GS, Hauptman PJ, Havranek EP, Krumholz HM, Mancini D, Riegel B, Spertus JA. Decision Making in Advanced Heart Failure. Circulation 2012, 125: 1928-1952. PMID: 22392529, PMCID: PMC3893703, DOI: 10.1161/cir.0b013e31824f2173.Peer-Reviewed Original Research
2011
A Model for Dissemination and Independent Analysis of Industry Data
Krumholz HM, Ross JS. A Model for Dissemination and Independent Analysis of Industry Data. JAMA 2011, 306: 1593-1594. PMID: 21990302, PMCID: PMC3688082, DOI: 10.1001/jama.2011.1459.Commentaries, Editorials and LettersReal-world Imperative of Outcomes Research
Krumholz HM. Real-world Imperative of Outcomes Research. JAMA 2011, 306: 754-755. PMID: 21846857, DOI: 10.1001/jama.2011.1170.Peer-Reviewed Original ResearchCardiac Care for Older Adults Time for a New Paradigm
Forman DE, Rich MW, Alexander KP, Zieman S, Maurer MS, Najjar SS, Cleveland JC, Krumholz HM, Wenger NK. Cardiac Care for Older Adults Time for a New Paradigm. Journal Of The American College Of Cardiology 2011, 57: 1801-1810. PMID: 21527153, PMCID: PMC4942282, DOI: 10.1016/j.jacc.2011.02.014.Peer-Reviewed Original Research
2010
Putting Ad Hoc PCI on Pause
Nallamothu BK, Krumholz HM. Putting Ad Hoc PCI on Pause. JAMA 2010, 304: 2059-2060. PMID: 21063016, DOI: 10.1001/jama.2010.1509.Peer-Reviewed Original ResearchInformed Consent to Promote Patient-Centered Care
Krumholz HM. Informed Consent to Promote Patient-Centered Care. JAMA 2010, 303: 1190-1191. PMID: 20332406, DOI: 10.1001/jama.2010.309.Peer-Reviewed Original Research
2008
Influence of Patients’ Socioeconomic Status on Clinical Management Decisions: A Qualitative Study
Bernheim SM, Ross JS, Krumholz HM, Bradley EH. Influence of Patients’ Socioeconomic Status on Clinical Management Decisions: A Qualitative Study. The Annals Of Family Medicine 2008, 6: 53-59. PMID: 18195315, PMCID: PMC2203396, DOI: 10.1370/afm.749.Peer-Reviewed Original ResearchConceptsClinical management decisionsPatients' socioeconomic statusClinical managementSocioeconomic statusPatient sPatient outcomesPrimary care physiciansStandard of careInfluence of patientLow socioeconomic statusVaried practice settingsHealth care qualitySES influencesCare physiciansHispanic ethnicityPhysician perspectivesPractice settingsCare qualityPatientsPhysiciansPatient interestMinority racial backgroundsInterview guideFinancial strainOutcomes
2007
Patterns of Weight Change Preceding Hospitalization for Heart Failure
Chaudhry SI, Wang Y, Concato J, Gill TM, Krumholz HM. Patterns of Weight Change Preceding Hospitalization for Heart Failure. Circulation 2007, 116: 1549-1554. PMID: 17846286, PMCID: PMC2892745, DOI: 10.1161/circulationaha.107.690768.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationHeart failureControl patientsFailure hospitalizationBody weightCase patientsWeight gainDecompensated heart failureHeart failure severityBaseline body weightHeart failure decompensationPatient's body weightAdjusted odds ratioCase-control studyGradual weight gainDisease management programsHigh-risk periodBasis of ageOdds ratioHospitalizationPatientsMean increaseDaily weightWeight changeHome monitoring
2005
Systolic Hypertension in Older Persons: Complexities in Clinical Decision Making
Foody JM, Chaudhry SI, Krumholz HM. Systolic Hypertension in Older Persons: Complexities in Clinical Decision Making. The American Journal Of Geriatric Cardiology 2005, 14: 325-330. PMID: 16276131, DOI: 10.1111/j.1076-7460.2005.04537.x.BooksConceptsOlder personsSystolic hypertensionHypertension treatment decisionsJoint National CommitteeBlood pressure controlHigh blood pressureEvidence-based careHealth care providersFinal management planHealth care decisionsOlder patientsBlood pressurePatient preferencesSeventh ReportTreatment preferencesTreatment decisionsIndividual patientsIndividualized riskTreatment goalsCare providersClinical decisionPressure controlMost health care decisionsCare decisionsPatients
1997
Determinants of Appropriate Use of Angiotensin-Converting Enzyme Inhibitors After Acute Myocardial Infarction in Persons ≥65 Years of Age
Krumholz H, Vaccarino V, Ellerbeck E, Kiefe C, Hennen J, Kresowik T, Gold J, Jencks S, Radford M. Determinants of Appropriate Use of Angiotensin-Converting Enzyme Inhibitors After Acute Myocardial Infarction in Persons ≥65 Years of Age. The American Journal Of Cardiology 1997, 79: 581-586. PMID: 9068512, DOI: 10.1016/s0002-9149(96)00819-3.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlabamaAngiotensin-Converting Enzyme InhibitorsConnecticutContraindicationsControlled Clinical Trials as TopicDecision MakingDiabetes ComplicationsDiureticsDrug PrescriptionsDrug UtilizationFemaleFollow-Up StudiesHeart FailureHospitalizationHumansIowaMaleMedicaidMultivariate AnalysisMyocardial InfarctionPatient DischargeRetrospective StudiesStroke VolumeTachycardia, VentricularUnited StatesVentricular Function, LeftWisconsinConceptsAcute myocardial infarctionACE inhibitorsMyocardial infarctionDischarge medicationsVentricular functionEnzyme inhibitorsLeft ventricular ejection fractionAngiotensin-converting enzyme inhibitorAngiotensin converting enzyme (ACE) inhibitorsVentricular Enlargement (SAVE) trialCongestive heart failureVentricular ejection fractionYears of ageEligible patientsPatient characteristicsAppropriate patientsDiabetes mellitusEjection fractionHeart failureLoop diureticsMultivariable analysisVentricular tachycardiaIdeal patientObservational studyPatients