Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages
Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceAntigens, ViralCD4 AntigensCell LineCells, CulturedChild, PreschoolFemaleGiant CellsHIV Core Protein p24HIV InfectionsHIV-1HumansInfantLeukocytes, MononuclearMacrophagesMolecular Sequence DataPhenotypeProspective StudiesProtein Structure, TertiaryReceptors, ChemokineTransfectionTropismU937 CellsViral ProteinsVirus ReplicationConceptsNSI virusesDisease stageSurrogate markerPediatric human immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionCell linesCo-receptor preferenceM-tropic virusesType 1 infectionT-cell tropicDual tropicInducing (NSI) virusesNSI isolatesAsymptomatic childrenMacrophage-tropicClinical progressionSymptomatic childrenV3 loopNSI phenotypeHIV-1Lymphotropic virusCategory A1Heterogeneous growth patternsGenetic features