2019
TDAG51 is a crucial regulator of maternal care and depressive-like behavior after parturition
Yun H, Park E, Choi S, Shin B, Yu J, Yu J, Amarasekara D, Kim S, Lee N, Choi J, Choi Y, Rho J. TDAG51 is a crucial regulator of maternal care and depressive-like behavior after parturition. PLOS Genetics 2019, 15: e1008214. PMID: 31251738, PMCID: PMC6599150, DOI: 10.1371/journal.pgen.1008214.Peer-Reviewed Original ResearchConceptsDepressive-like behaviorPostpartum depressionDevelopment of postpartum depressionImpaired maternal behaviorRegulation of maternal careMonoamine neurotransmitter levelsCombination of physical changesNest-building testInfluence of genetic risk factorsTDAG51 deficiencyMaternity careGenetic risk factorsPup retrievalMental disordersPsychiatric illnessNeurotransmitter levelsMaternal behaviorPostpartumRisk factorsDepressionBuilding testsT-cell death-associated geneDeath-associated genesNursesCare
2007
Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene
Park E, Choi S, Kim J, Jeong Y, Choe J, Park C, Choi Y, Rho J. Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochemical And Biophysical Research Communications 2007, 363: 971-977. PMID: 17927961, DOI: 10.1016/j.bbrc.2007.09.103.Peer-Reviewed Original ResearchConceptsTumor necrosis factor receptor (TNFR)-associated factorsTRAF-interacting proteinCylindromatosis tumor suppressor geneFamilial cylindromatosis tumour suppressor geneHomozygous mouse embryosComplex in vitroEarly embryonic lethalityTumor suppressor geneExcessive cell deathNF-kappaB signalingAdaptor moleculeEmbryonic lethalityProliferation defectEmbryonic development in vivoSignaling in vitroSuppressor geneSignaling cascadesCell deathActivity in vitroDevelopment in vivoTargeted disruptionNF-kappaB activation in vitroFunctional roleCell proliferationMouse embryos